Drug Description in Trials / DrugBank / KEGG DRUG

  

Search results

No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Water 💬 [1] Water[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; --[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
2 Oxygen 💬 [1] Oxygen[3] Medical air; Nitrogen; Oxygen; --[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
3 Alanine 💬 [1] Alanine[2] Alanine; L-alanine; --[4] 6, 13, 298, 299 💬
4 Glutathione 💬 [1] Glutathione[2] Glutathione; Reduced Glutathione; --[2] 6, 299 💬
5 Serine 💬 [1] Serine[2] L-Serine; Serine; --[4] 2, 6, 86, 96 💬
6 Tryptophan 💬 [1] Tryptophan[2] Propanoic acid; Tryptophan; --[1] 6 💬
7 Tyrosine 💬 [1] Tyrosine[4] Alanine; L-Tyrosine; Propanoic acid; Tyrosine; --[4] 6, 86, 111, 298 💬
8 Glycerin 💬 [1] Glycerin[2] Bee venom; Glycerol; --[5] 6, 13, 79, 316, 317 💬
9 Leucine 💬 [1] Leucine[2] L-leucine; Leucine; --[6] 6, 19, 65, 283, 284, 299 💬
10 Oxiglutatione 💬 [1] Glutathione[2] GLUTATHIONE; Reduced glutathione; --[2] 6, 299 💬
11 Niacinamide 💬 [1] Nicotinamide[3] Multivitamin; Niacinamide; NICOTINAMIDE; --[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
12 Anhydrous lactose 💬 [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310 💬
13 Niacin 💬 [1] Niacin[2] Niacin; Nicotinic acid; --[3] 6, 78, 79 💬
14 Inosine 💬 [1] Inosine[1] Inosine; --[5] 2, 6, 13, 17, 122 💬
15 Citicoline 💬 [1] Citicoline[1] Citicolina; --[1] 6 💬
16 Levodopa 💬 [1] Levodopa[9] Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[6] 6, 17, 90, 140, 164, 201 💬
17 Mannitol 💬 [1] Mannitol[4] Aridol; Bronchitol; Mannite; Mannitol; --[7] 6, 13, 28, 60, 96, 113, 299 💬
18 Folic acid 💬 [1] Folic acid[5] Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE; --[6] 6, 41, 46, 49, 84, 296 💬
19 Nitric oxide 💬 [1] Nitric Oxide[3] INOmax; Nitric Oxide; Nitrosyl; --[7] 85, 86, 88, 210, 251, 294, 299 💬
20 Nitrogen 💬 [1] Nitrogen[1] Nitrogen; --[5] 5, 6, 17, 211, 299 💬
21 Hydrocortisone 💬 [1] Hydrocortisone[6] Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
22 Oxytocin 💬 [1] Oxytocin[2] Oxytocin; Syntocinon; [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
23 Tacrolimus 💬 [1] Tacrolimus[2] Prograf; Tacrolimus; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
24 Albendazole 💬 [1] Albendazole[2] Albendazole; Eskazole; --[1] 96 💬
25 Erythromycin 💬 [1] Erythromycin[1] Erythromycin; --[5] 6, 36, 164, 228, 291 💬
26 Cyanocobalamin 💬 [1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12; --[5] 6, 13, 201, 229, 299 💬
27 Inulin 💬 [1] Inulin[1] Inulin; --[4] 6, 96, 156, 299 💬
28 Cholecalciferol 💬 [1] Cholecalciferol[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
29 Ampicillin 💬 [1] Ampicillin[1] ABPC; --[1] 84 💬
30 Rifampin 💬 [1] Rifampicin[2] Rifampicin; Rifampin; --[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
31 Acetaminophen 💬 [1] Acetaminophen[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
32 Acetylcysteine 💬 [1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-acetylcysteine; --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
33 Allopurinol 💬 [1] Allopurinol[2] ALLOPURINOL; ALLOPURINOL SODIUM; [1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[7] 6, 46, 57, 60, 66, 96, 97 💬
34 Amoxicillin 💬 [1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --[7] 6, 46, 63, 96, 97, 222, 299 💬
35 Azathioprine 💬 [1] Azathioprine[3] Azathioprine; Azatioprina; Imuran; --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
36 Bumetanide 💬 [1] Bumetanide[1] Bumetanide; [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 158 💬
37 Capsaicin 💬 [1] Capsaicin[2] Capsaicin; Qutenza; [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
38 Captopril 💬 [1] Captopril[1] Captopril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 17, 86 💬
39 Carbamazepine 💬 [1] Carbamazepine[1] Carbamazepine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231 💬
40 Clarithromycin 💬 [1] Clarithromycin[1] CLARITHROMYCIN; --[8] 6, 63, 84, 96, 97, 222, 228, 299 💬
41 Clonazepam 💬 [1] Clonazepam[1] Clonazepam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
42 Clonidine 💬 [1] Clonidine[4] Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78 💬
43 Clozapine 💬 [1] Clozapine[1] CLOZAPINE; [11] ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[8] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[1] 6 💬
44 Desmopressin 💬 [1] Desmopressin[5] DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin; [2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288 💬
45 Dihydrotachysterol 💬 [1] Dihydrotachysterol[0] [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬-
46 Famotidine 💬 [1] Famotidine[2] FAMOTIDINA; Famotidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[6] 6, 46, 61, 86, 98, 107 💬
47 Finasteride 💬 [1] Finasteride[1] Finasteride; [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6 💬
48 Furosemide 💬 [1] Furosemide[2] Furosemide; Furosemide Injection; [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[2] 6, 86 💬
49 Gabapentin 💬 [1] Gabapentin[4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN; [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
50 Isradipine 💬 [1] Isradipine[1] Isradipine; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
51 Lidocaine 💬 [1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
52 Lovastatin 💬 [1] Lovastatin[1] Lovastatin; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
53 Tropicamide 💬 [1] Tropicamide[1] Tropicamide; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
54 Valproic acid 💬 [1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic Acid; [7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
55 Zolmitriptan 💬 [1] Zolmitriptan[1] Zolmitriptan; [2] HTR1B,
HTR1D 💬		[4] Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
56 Nadolol 💬 [1] Nadolol[1] Nadolol; [2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
57 Simvastatin 💬 [1] Simvastatin[3] Simvastatin; Simvastatina; Simvastatine; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
58 Omeprazole 💬 [1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
59 Ondansetron 💬 [1] Ondansetron[1] Ondansetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107 💬
60 Oxybutynin 💬 [1] Oxybutynin[1] Oxybutynin; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
61 Pyrimethamine 💬 [1] Pyrimethamine[2] Daraprim; Pyrimethamine; --[4] 2, 4, 19, 65 💬
62 Dexmedetomidine 💬 [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
63 Pilocarpine 💬 [1] Pilocarpine[2] Pilocarpine; Pilocarpine Hydrochloride; [2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 53, 299 💬
64 Caffeine 💬 [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
65 Topiramate 💬 [1] Topiramate[2] TOPAMAX; Topiramate; [36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
66 Zonisamide 💬 [1] Zonisamide[2] Zonegran; Zonisamide; [8] CACNA1G,
CACNA1H,
CACNA1I,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[11] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, GnRH secretion, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus 💬[1] 6 💬
67 Isoflurane 💬 [1] Isoflurane[1] Isoflurane; --[1] 6 💬
68 Sevoflurane 💬 [1] Sevoflurane[1] Sevoflurane; --[7] 6, 21, 22, 34, 98, 225, 296 💬
69 Etomidate 💬 [1] Etomidate[1] Etomidate; [1] GABRA1 💬[6] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[1] 6 💬
70 Propofol 💬 [1] Propofol[2] Propofol; Propofol Injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[8] 6, 21, 22, 34, 46, 70, 98, 296 💬
71 Midazolam 💬 [1] Midazolam[2] Midazolam; Midazolam injection; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
72 Carbidopa 💬 [1] Carbidopa[8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo; [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
73 Repaglinide 💬 [1] Repaglinide[1] Repaglinide; [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
74 Flumazenil 💬 [1] Flumazenil[1] Flumazenil; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
75 Levetiracetam 💬 [1] Levetiracetam[2] KEPPRA; Levetiracetam; [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
76 Ursodiol 💬 [1] Ursodeoxycholic acid[4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk; [1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
77 Entacapone 💬 [1] Entacapone[5] COMTAN; Comtess; ENTACAPONA; ENTACAPONE; Stalevo; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17 💬
78 Botulinum toxin type A 💬 [1] Botulinum toxin type A[8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin; [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
79 Tolcapone 💬 [1] Tolcapone[3] Tasmar; Tolcapon; Tolcapone; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127 💬
80 Hydrocortisone cypionate 💬 [1] Hydrocortisone cypionate[1] Cortef; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
81 Cabergoline 💬 [1] Cabergoline[3] CABERGOLINA; Cabergoline; DOSTINEX; [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75 💬
82 Ubidecarenone 💬 [1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10; --[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
83 Exametazime 💬 [1] Exametazime[1] Exametazime; --[1] 6 💬
84 Aripiprazole 💬 [1] Aripiprazole[1] Aripiprazole; [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206 💬
85 Magnesium oxide 💬 [1] Magnesium oxide[1] Magnesium oxide; --[3] 6, 166, 291 💬
86 Febuxostat 💬 [1] Febuxostat[1] Febuxostat; [1] XDH 💬[6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13 💬
87 Sulpiride 💬 [1] Sulpiride[0] [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬-
88 Josamycin 💬 [1] Josamycin[0] ---
89 Droxidopa 💬 [1] Droxidopa[4] DOPS; Droxidopa; L-DOPS; Northera; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
90 Zopiclone 💬 [1] Zopiclone[1] Zopiclone; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6 💬
91 Hydrocortisone succinate 💬 [1] Hydrocortisone succinate[2] HYDROCORTISONE HYDROGEN SUCCINATE; Solu-Cortef; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
92 Caffeine hydrate 💬 [1] Caffeine[1] Caffeine; [11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265 💬
93 Edaravone 💬 [1] Edaravone[3] Edaravone; Methylphenylpyrazolone; Norphenazone; --[3] 2, 6, 22 💬
94 Domperidone 💬 [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
95 Idebenone 💬 [1] Idebenone[2] Idebenone; Raxone; --[6] 6, 8, 13, 18, 113, 302 💬
96 Modafinil 💬 [1] Modafinil[2] Modafinil; Provigil; --[5] 6, 13, 49, 93, 113 💬
97 Silodosin 💬 [1] Silodosin[2] Silodosin; Silodyx; [1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
98 Zoledronic acid 💬 [1] Zoledronic acid[4] Aclasta; Zoledronate; Zoledronic Acid; Zometa; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
99 Tadalafil 💬 [1] Tadalafil[4] Adcirca; Cialis; Tadalafil; TADALAFILO; [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210 💬
100 Potassium carbonate 💬 [1] Potassium carbonate[0] ---
101 Sodium chloride 💬 [1] Sodium chloride[6] Lactated Ringers; Natriumchlorid; REBIF; SALINE; SODIUM CHLORIDE; Sporanox; --[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
102 Tulobuterol 💬 [1] Tulobuterol[1] Tulobuterol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
103 Maltodextrin 💬 [1] Maltodextrin[1] Maltodextrin; --[4] 6, 13, 96, 97 💬
104 Vitamin E 💬 [1] Vitamin E[2] Alpha-tocopherol; Vitamin E; --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
105 Dipivefrin 💬 [1] Dipivefrin[2] Dipivefrin; Dipivefrine; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
106 Sertraline 💬 [1] Sertraline[1] Sertraline; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206 💬
107 Paroxetine 💬 [1] Paroxetine[1] Paroxetine; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
108 Aspartame 💬 [1] Aspartame[0] [2] TAS1R2,
TAS1R3 💬		[2] Carbohydrate digestion and absorption, Taste transduction 💬-
109 Rifaximin 💬 [1] Rifaximin[3] Rifaximin; RIFAXIMINA; Xifaxan; --[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
110 Moclobemide 💬 [1] Moclobemide[1] MOCLOBEMIDE; [1] MAOA 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
111 Agomelatine 💬 [1] Agomelatine[1] Agomelatine; [3] HTR2C,
MTNR1A,
MTNR1B 💬		[6] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
112 Iproniazid 💬 [1] Iproniazid[1] IPRONIAZID; [2] MAOA,
MAOB 💬		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
113 Eszopiclone 💬 [1] Eszopiclone[2] Eszopiclone; Zopiclone; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
114 Iloperidone 💬 [1] Iloperidone[1] Iloperidone; [4] DRD2,
HTR2A,
HTR2B,
HTR2C 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 6 💬
115 Ramelteon 💬 [1] Ramelteon[2] Ramelteon; ROZEREM; [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46 💬
116 Talampanel 💬 [1] Talampanel[1] Talampanel; [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6 💬
117 Rimabotulinumtoxin B 💬 [1] Botulinum toxin type B[3] Botulinum toxin type B; MYOBLOC; NEUROBLOC; [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51 💬
118 Ammonia solution, strong 💬 [1] Ammonia[1] Ammonia; --[2] 6, 296 💬
119 Benserazide 💬 [1] Benserazide[1] BENSERAZIDE; [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
120 Bromocriptine 💬 [1] Bromocriptine[1] Bromocriptine; [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 74 💬
121 Armodafinil 💬 [1] Armodafinil[2] Armodafinil; MODAFINIL; [1] SLC6A3 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
122 Lactose 💬 [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310 💬
123 Filgrastim 💬 [1] Filgrastim[7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio; [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
124 Nicotine 💬 [1] Nicotine[2] Nicotine; Nicotine gum; [16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬		[8] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬[3] 6, 13, 84 💬
125 Polyethylene glycol 3350 💬 [1] Polyethylene glycol[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350; --[7] 6, 78, 96, 97, 235, 276, 299 💬
126 Cyanocobalamin Co 57 💬 [1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12; --[5] 6, 13, 201, 229, 299 💬
127 Cyanocobalamin Co 58 💬 [1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12; --[5] 6, 13, 201, 229, 299 💬
128 Cyanocobalamin Co 60 💬 [1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12; --[5] 6, 13, 201, 229, 299 💬
129 Darifenacin 💬 [1] Darifenacin[2] Darifenacin; Emselex; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
130 Selegiline 💬 [1] Selegiline[2] SELEGILINE; Zelapar; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
131 Dextromethorphan 💬 [1] Dextromethorphan[4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
132 Rivastigmine 💬 [1] Rivastigmine[3] EXELON; Rivastigmine; Rivastigmine Transdermal System; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13 💬
133 Exenatide 💬 [1] Exenatide[3] BYDUREON; Byetta; EXENATIDE; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
134 Dalfampridine 💬 [1] Dalfampridine[7] 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
135 Galantamine 💬 [1] Galantamine[2] GALANTAMINE; Galantamine hydrobromide; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[2] 6, 127 💬
136 Lactomin 💬 [1] Lactobacillus acidophilus[4] Acidophilus; Lacteol; Lactobacillus; Lactobacillus acidophilus; --[3] 6, 49, 97 💬
137 Lactobacillus casei 💬 [1] Lactobacillus casei[2] Fusion; Lactobacillus casei; --[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
138 Guar gum 💬 [1] Guar gum[1] Guar gum; --[1] 6 💬
139 Istradefylline 💬 [1] Istradefylline[1] ISTRADEFYLLINE; [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
140 Liatermin 💬 [1] Liatermin[2] Liatermin; R-metHuGDNF; --[1] 6 💬
141 Lithium citrate 💬 [1] Lithium citrate[2] Lithium; LITHIUM CITRATE; --[5] 2, 5, 6, 7, 8 💬
142 Lubiprostone 💬 [1] Lubiprostone[1] Lubiprostone; [1] CLCN2 💬[1] Mineral absorption 💬[4] 6, 13, 290, 299 💬
143 Metformin 💬 [1] Metformin[5] Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; METFORMINA; Metformine; [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
144 Methylphenidate 💬 [1] Methylphenidate[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin; [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
145 Minocycline 💬 [1] Minocycline[3] Minocycline; Minocycline Hydrochloride; Minomycin; --[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
146 Nabilone 💬 [1] Nabilone[1] NABILONE; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
147 Nalmefene 💬 [1] Nalmefene[1] Nalmefene; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
148 Naltrexone 💬 [1] Naltrexone[2] Naltrexone; Naltrexone Hydrochloride; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
149 Nitisinone 💬 [1] Nitisinone[2] NITISINONE; Orfadin; [1] HPD 💬[5] Biosynthesis of cofactors, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism, Ubiquinone and other terpenoid-quinone biosynthesis 💬[3] 6, 164, 241 💬
150 Oxycodone 💬 [1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
151 Plantago seed 💬 [1] Plantago seed[2] Psyllium; Psyllium husk; --[3] 6, 28, 97 💬
152 Pramipexole 💬 [1] Pramipexole[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20 💬
153 Rotigotine 💬 [1] Rotigotine[3] NEUPRO; ROTIGOTINA; ROTIGOTINE; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
154 Sargramostim 💬 [1] Sargramostim[2] Leukine; Sargramostim; [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285 💬
155 Sodium oxybate 💬 [1] Sodium oxybate[1] Sodium Oxybate; --[2] 6, 149 💬
156 Sulfachlorpyridazine 💬 [1] Sulfachlorpyridazine[0] ---
157 Liraglutide 💬 [1] Liraglutide[2] LIRAGLUTIDE; Saxenda; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 6, 75, 193 💬
158 Wheat 💬 [1] Wheat[1] Wheat; --[2] 6, 53 💬
159 Green tea leaf 💬 [1] Green tea leaf[4] Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract; --[4] 6, 17, 28, 46 💬
160 Acamprosate 💬 [1] Acamprosate[1] Acamprosate; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206 💬
161 Ademetionine 💬 [1] Ademetionine[2] SAM-e; SAMe; --[2] 6, 93 💬
162 Heptaminol 💬 [1] Heptaminol[1] Heptaminol; --[1] 6 💬
163 Fesoterodine 💬 [1] Fesoterodine[1] Fesoterodine; [2] CHRM2,
CHRM3 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
164 Melevodopa 💬 [1] Melevodopa[1] Melevodopa; --[1] 6 💬
165 Piribedil 💬 [1] Piribedil[1] Piribedil; [2] DRD2,
DRD3 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
166 Melperone 💬 [1] Melperone[1] Melperone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
167 Deferiprone 💬 [1] Deferiprone[2] DEFERIPRONE; Ferriprox; --[6] 2, 6, 18, 120, 122, 233 💬
168 Amantadine 💬 [1] Amantadine[3] Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127 💬
169 Ambroxol 💬 [1] Ambroxol[1] Ambroxol; --[2] 6, 19 💬
170 Amoxicillin 💬 [1] Amoxicillin[4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin; --[7] 6, 46, 63, 96, 97, 222, 299 💬
171 Apomorphine 💬 [1] Apomorphine[4] APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride; [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
172 Atomoxetine 💬 [1] Atomoxetine[2] Atomoxetine; Strattera; [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
173 Buspirone 💬 [1] Buspirone[2] Buspirone; Buspirone Hydrochloride; [2] DRD2,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 51 💬
174 Ceftriaxone 💬 [1] Ceftriaxone[1] CEFTRIAXONE; --[4] 2, 6, 46, 97 💬
175 Citalopram 💬 [1] Citalopram[1] Citalopram; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
176 Clenbuterol 💬 [1] Clenbuterol[1] Clenbuterol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 1, 2, 6, 256 💬
177 Deanol 💬 [1] Deanol[1] Deanol; --[1] 6 💬
178 Delorazepam 💬 [1] Delorazepam[0] [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬-
179 Dihydroergotoxine 💬 [1] Dihydroergotoxine[1] Dihydroergotoxine; --[1] 6 💬
180 Domperidone maleate 💬 [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
181 Donepezil 💬 [1] Donepezil[3] ARICEPT; Donepezil; Donepezil Hydrochloride; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
182 Dopamine 💬 [1] Dopamine[2] Dopamina; Dopamine; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299 💬
183 Doxepin 💬 [1] Doxepin[1] Doxepin; [3] HRH1,
SLC6A2,
SLC6A4 💬		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
184 Duloxetine 💬 [1] Duloxetine[3] CYMBALTA; Duloxetine; Duloxetine hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
185 Escitalopram 💬 [1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate; [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
186 Flecainide 💬 [1] Flecainide[3] Flecainide; FLECAINIDE ACETATE; Flecainidum; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
187 Fludrocortisone 💬 [1] Fludrocortisone[1] Fludrocortisone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
188 Ketamine 💬 [1] Ketamine[2] Ketamine; NMDA; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
189 Lidocaine hydrochloride monohydrate 💬 [1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
190 Lisuride 💬 [1] Lisuride[1] LISURIDE; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 86 💬
191 Melatonin 💬 [1] Melatonin[2] Circadin; Melatonin; [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
192 Memantine 💬 [1] Memantine[3] EBIXA; Memantine; Memantine hydrochloride; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
193 Midodrine 💬 [1] Midodrine[2] Midodrine; MIDODRINE HYDROCHLORIDE; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[3] 6, 17, 58 💬
194 Montelukast 💬 [1] Montelukast[3] Montelukast; MONTELUKAST SODIUM; Singulair; [1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
195 Moxifloxacin 💬 [1] Moxifloxacin[2] Moxifloxacin; Moxifloxacin Hydrochloride; --[9] 2, 6, 46, 49, 85, 86, 113, 240, 299 💬
196 Naloxone 💬 [1] Naloxone[2] Naloxone; NALOXONE HYDROCHLORIDE; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
197 Nortriptyline 💬 [1] Nortriptyline[2] Nortriptyline; Nortriptyline hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 226 💬
198 Oxybuprocaine 💬 [1] Oxybuprocaine[1] Oxybuprocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
199 Pergolide 💬 [1] Pergolide[1] PERGOLIDE; [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
200 Phenelzine 💬 [1] Phenelzine[1] Nardil; [2] MAOA,
MAOB 💬		[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6 💬
201 Pioglitazone 💬 [1] Pioglitazone[1] Pioglitazone; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
202 Propranolol 💬 [1] Propranolol[2] Propanolol; Propranolol; [3] ADRB1,
ADRB2,
ADRB3 💬		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 158, 167, 227, 278, 296 💬
203 Pyridoxine 💬 [1] Pyridoxine[2] PYRIDOXINE; Vitamin B6; --[5] 6, 93, 145, 206, 320 💬
204 Quetiapine 💬 [1] Quetiapine[2] Quetiapine; Seroquel; [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
205 Quinine 💬 [1] Quinine[0] ---
206 Quinine dihydrochloride 💬 [1] Quinine[0] ---
207 Rasagiline 💬 [1] Rasagiline[4] AZILECT; Rasagilina; RASAGILINE; RASAGILINE MESYLATE; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
208 Remifentanil 💬 [1] Remifentanil[2] Remifentanil; Remifentanyl; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70 💬
209 Ropinirole 💬 [1] Ropinirole[3] REQUIP; ROPINIROLE; Ropinirole Hydrochloride; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 309 💬
210 Rosuvastatin 💬 [1] Rosuvastatin[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
211 Sildenafil 💬 [1] Sildenafil[6] Mysildecard; Revatio; Sildenafil; Sildenafil citrate; SILDENAFILO; Viagra; [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
212 Sitagliptin 💬 [1] Sitagliptin[1] Sitagliptin; [1] DPP4 💬[1] Protein digestion and absorption 💬[4] 6, 75, 233, 299 💬
213 Solifenacin 💬 [1] Solifenacin[2] Solifenacin; Solifenacin Succinate; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
214 Sulfanilamide 💬 [1] Sulfanilamide[0] ---
215 Tacrolimus 💬 [1] Tacrolimus[2] Prograf; Tacrolimus; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
216 Terazosin 💬 [1] Terazosin[1] Terazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6 💬
217 Trihexyphenidyl 💬 [1] Trihexyphenidyl[1] Trihexyphenidyl; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
218 Trimethobenzamide 💬 [1] Trimethobenzamide[3] Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride; --[1] 6 💬
219 Varenicline 💬 [1] Varenicline[2] Champix; VARENICLINE; [2] CHRNA4,
CHRNB2 💬		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53 💬
220 Venlafaxine 💬 [1] Venlafaxine[2] Venlafaxine; Venlafaxine Hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
221 Warfarin 💬 [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
222 Yohimbine 💬 [1] Yohimbine[1] Yohimbine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 6 💬
223 Zoledronic acid 💬 [1] Zoledronic acid[4] ACLASTA; Zoledronate; Zoledronic acid; Zometa; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
224 Zolpidem 💬 [1] Zolpidem[2] Zolpidem; Zolpidem Tartrate; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 5, 6, 46 💬
225 Nilotinib 💬 [1] Nilotinib[2] Nilotinib; Tasigna; [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬		[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
226 Perampanel 💬 [1] Perampanel[2] Fycompa; PERAMPANEL; [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬		[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
227 German chamomile flower 💬 [1] Chamomile[2] Chamomile; MATRICARIA FLOWER; --[2] 6, 97 💬
228 Levomefolic acid 💬 [1] Levomefolic acid[1] L-methylfolate; --[1] 6 💬
229 Linaclotide 💬 [1] Linaclotide[1] Linaclotide; [1] GUCY2C 💬[2] Metabolic pathways, Purine metabolism 💬[2] 6, 97 💬
230 Pardoprunox 💬 [1] Pardoprunox[1] Pardoprunox; [3] DRD2,
DRD3,
HTR1A 💬		[10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
231 Mirabegron 💬 [1] Mirabegron[1] Mirabegron; [1] ADRB3 💬[8] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
232 Nelotanserin 💬 [1] Nelotanserin[1] Nelotanserin; [1] HTR2A 💬[5] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6 💬
233 Saracatinib 💬 [1] Saracatinib[1] Saracatinib; [2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272 💬
234 Preladenant 💬 [1] Preladenant[1] Preladenant; [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
235 Lixisenatide 💬 [1] Lixisenatide[1] Lixisenatide; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
236 Bavisant 💬 [1] Bavisant[1] Bavisant; [1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6 💬
237 Pridopidine 💬 [1] Pridopidine[1] Pridopidine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
238 Semaglutide 💬 [1] Semaglutide[1] Semaglutide; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6 💬
239 Suvorexant 💬 [1] Suvorexant[1] Suvorexant; [2] HCRTR1,
HCRTR2 💬		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
240 Glycerol phenylbutyrate 💬 [1] Glycerol phenylbutyrate[3] Glycerol Phenylbutyrate; GT4P; RAVICTI; --[3] 6, 251, 299 💬
241 Safinamide 💬 [1] Safinamide[3] Safinamida; SAFINAMIDE; Xadago; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[2] 6, 17 💬
242 Tozadenant 💬 [1] Tozadenant[1] TOZADENANT; [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6 💬
243 Vortioxetine 💬 [1] Vortioxetine[1] Vortioxetine; [7] HTR1A,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E,
SLC6A4 💬		[5] Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
244 Masitinib 💬 [1] Masitinib[1] Masitinib; [1] KIT 💬[11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
245 Pitolisant 💬 [1] Pitolisant[1] Pitolisant; [1] HRH3 💬[1] Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
246 Elobixibat 💬 [1] Elobixibat[1] Elobixibat; [1] SLC10A2 💬[1] Bile secretion 💬[1] 6 💬
247 Opicapone 💬 [1] Opicapone[2] Ongentys; OPICAPONE; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
248 Rasagiline tartrate 💬 [1] Rasagiline[4] Azilect; Rasagilina; Rasagiline; Rasagiline mesylate; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[4] 2, 5, 6, 17 💬
249 Cannabidiol 💬 [1] Cannabidiol[4] CANNABIDIOL; Epidiolex; Epidyolex; SATIVEX; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
250 Prasinezumab 💬 [1] Prasinezumab[1] Prasinezumab; [1] SNCA 💬[3] Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬[1] 6 💬
251 Tavapadon 💬 [1] Tavapadon[2] PF-06649751; TAVAPADON; [2] DRD1,
DRD5 💬		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6 💬
252 Venglustat 💬 [1] Venglustat[2] GENZ-682452; Venglustat; [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[3] 6, 19, 67 💬
253 Ampreloxetine 💬 [1] Ampreloxetine[1] Ampreloxetine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17 💬
254 Foslevodopa 💬 [1] Foslevodopa[1] Foslevodopa; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
255 Foscarbidopa 💬 [1] Foscarbidopa[1] Foscarbidopa; --[1] 6 💬
256 Valiloxybate 💬 [1] Valiloxybate[1] Valiloxybate; [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 6 💬