1 |
Water
💬
| [1] Water Water | [8] AVONEX AVONEX; ENBREL; Hiberix; INDOCYANINE GREEN; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; | - | - | [21] 2 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬 |
2 |
Leucine
💬
| [1] Leucine Leucine | [2] L-leucine L-leucine; Leucine; | - | - | [6] 6 6, 19, 65, 283, 284, 299 💬 |
3 |
Adenosine
💬
| [1] Adenosine Adenosine | [2] Adenosine Adenosine; Ginseng; | [4] ADORA1 ADORA1, ADORA2A, ADORA2B, ADORA3 💬 | [12] Alcoholism Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [3] 13 13, 58, 65 💬 |
4 |
Estradiol
💬
| [1] Estradiol Estradiol | [1] Estradiol Estradiol; | [2] ESR1 ESR1, ESR2 💬 | [10] Breast cancer Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬 | [7] 13 13, 46, 49, 65, 76, 226, 299 💬 |
5 |
Tacrolimus
💬
| [1] Tacrolimus Tacrolimus | [2] Prograf Prograf; Tacrolimus; | [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [34] 2 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
6 |
Etoposide
💬
| [1] Etoposide Etoposide | [1] Etoposide Etoposide; | [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [11] 11 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬 |
7 |
Ibuprofen
💬
| [1] Ibuprofen Ibuprofen | [2] Ibuprofen Ibuprofen; IBUPROFEN 200MG; | [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [7] 13 13, 46, 65, 107, 113, 271, 299 💬 |
8 |
Methotrexate
💬
| [1] Methotrexate Methotrexate | [6] Methotrexat Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; Metotrexato; Méthotrexate; | [2] DHFR DHFR, DHFR2 💬 | [5] Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬 | [38] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
9 |
Mercaptopurine
💬
| [1] Mercaptopurine Mercaptopurine | [4] 6-mercaptopurine 6-mercaptopurine; 6-MP; MERCAPTOPURINE; PURINETHOL; | [1] HPRT1 HPRT1 💬 | [4] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [4] 65 65, 96, 97, 164 💬 |
10 |
Cytarabine
💬
| [1] Cytarabine Cytarabine | [1] Cytarabine Cytarabine; | - | - | [7] 11 11, 13, 14, 25, 49, 60, 65 💬 |
11 |
Cyclosporine
💬
| [1] Cyclosporine Cyclosporine | [10] Ciclosporin Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; RESTASIS; | [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [44] 11 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
12 |
Cholecalciferol
💬
| [1] Cholecalciferol Cholecalciferol | [5] CHOLECALCIFEROL CHOLECALCIFEROL; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3; | [1] VDR VDR 💬 | [5] Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [16] 6 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬 |
13 |
Azathioprine
💬
| [1] Azathioprine Azathioprine | [3] Azathioprine Azathioprine; Azatioprina; Imuran; | - | - | [21] 6 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬 |
14 |
Baclofen
💬
| [1] Baclofen Baclofen | [2] Baclofen Baclofen; Kemstro; | [2] GABBR1 GABBR1, GABBR2 💬 | [7] Estrogen signaling pathway Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬 | [8] 2 2, 10, 13, 18, 65, 70, 149, 206 💬 |
15 |
Betamethasone
💬
| [1] Betamethasone Betamethasone | [1] Betamethasone Betamethasone; | [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [8] 2 2, 28, 46, 65, 83, 90, 96, 235 💬 |
16 |
Busulfan
💬
| [1] Busulfan Busulfan | [3] BUSILVEX BUSILVEX; Busulfan; BUSULFANO; | - | - | [13] 19 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬 |
17 |
Clonidine
💬
| [1] Clonidine Clonidine | [4] Clonidin Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; | [3] ADRA2A ADRA2A, ADRA2B, ADRA2C 💬 | [2] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬 | [4] 6 6, 65, 70, 78 💬 |
18 |
Cyclophosphamide
💬
| [1] Cyclophosphamide Cyclophosphamide | [6] Ciclofosfamida Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan; | - | - | [44] 11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬 |
19 |
Danazol
💬
| [1] Danazol Danazol | [1] Danazol Danazol; | [3] AR AR, ESR1, PGR 💬 | [12] Breast cancer Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬 | [5] 60 60, 63, 64, 65, 285 💬 |
20 |
Dexamethasone
💬
| [1] Dexamethasone Dexamethasone | [5] Decadron Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex; | [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [22] 13 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
21 |
Hydroxyurea
💬
| [1] Hydroxyurea Hydroxyurea | [1] Hydroxyurea Hydroxyurea; | [1] RRM2 RRM2 💬 | [7] Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬 | [8] 3 3, 13, 19, 20, 65, 85, 86, 284 💬 |
22 |
Isoniazid
💬
| [1] Isoniazid Isoniazid | [1] Isoniazid Isoniazid; | - | - | [1] 254 254 💬 |
23 |
Itraconazole
💬
| [1] Itraconazole Itraconazole | [2] Itraconazole Itraconazole; SPORANOX; | - | - | [6] 3 3, 46, 65, 96, 227, 299 💬 |
24 |
Melphalan
💬
| [1] Melphalan Melphalan | [3] ALKERAN ALKERAN; Melphalan; Melphalan Hydrochloride; | - | - | [15] 11 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬 |
25 |
Valproic acid
💬
| [1] Valproic acid Valproic acid | [3] Valproate Valproate; VALPROATE SODIUM; Valproic Acid; | [7] ABAT ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬 | [17] Alanine, aspartate and glutamate metabolism Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬 | [10] 2 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬 |
26 |
Methylprednisolone
💬
| [1] Methylprednisolone Methylprednisolone | [4] Medrol Medrol; Methylprednisolon; METHYLPREDNISOLONE; Methylprednisolone acetate; | [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [46] 2 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
27 |
Ranitidine
💬
| [1] Ranitidine Ranitidine | [1] Ranitidine Ranitidine; | [1] HRH2 HRH2 💬 | [3] Calcium signaling pathway Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬 | [2] 13 13, 65 💬 |
28 |
Prednisolone
💬
| [1] Prednisolone Prednisolone | [3] Prednisolona Prednisolona; Prednisolone; Prednisolonum; | [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [42] 3 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
29 |
Prednisone
💬
| [1] Prednisone Prednisone | [3] Prednisona Prednisona; Prednisone; RAYOS; | [1] NR3C1 NR3C1 💬 | [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [45] 2 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
30 |
Pyrimethamine
💬
| [1] Pyrimethamine Pyrimethamine | [2] Daraprim Daraprim; PYRIMETHAMINE; | - | - | [4] 2 2, 4, 19, 65 💬 |
31 |
Sulfadoxine
💬
| [1] Sulfadoxine Sulfadoxine | [1] Sulfadoxine Sulfadoxine; | - | - | [1] 65 65 💬 |
32 |
Thiotepa
💬
| [1] Thiotepa Thiotepa | [1] Thiotepa Thiotepa; | - | - | [12] 13 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬 |
33 |
Interferon gamma-1b
💬
| [1] Interferon gamma-1b Interferon gamma-1b | [2] ACTIMMUNE ACTIMMUNE; Interferon gamma-1b; | [2] IFNGR1 IFNGR1, IFNGR2 💬 | [18] Chagas disease Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬 | [7] 18 18, 65, 85, 228, 299, 301, 326 💬 |
34 |
Aldesleukin
💬
| [1] Aldesleukin Aldesleukin | [4] ALDESLEUKIN ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-2; | [3] IL2RA IL2RA, IL2RB, IL2RG 💬 | [14] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬 | [6] 2 2, 35, 49, 65, 96, 97 💬 |
35 |
Mycophenolate mofetil
💬
| [1] Mycophenolate mofetil Mycophenolate mofetil | [3] CELLCEPT CELLCEPT; MYCOPHENOLATE MOFETIL; Mycophenolate mofetil TEVA; | [2] IMPDH1 IMPDH1, IMPDH2 💬 | [4] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [34] 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
36 |
Sirolimus
💬
| [1] Sirolimus Sirolimus | [3] Rapamune Rapamune; Rapamycin; Sirolimus; | [1] MTOR MTOR 💬 | [51] AMPK signaling pathway AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬 | [40] 2 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
37 |
Thalidomide
💬
| [1] Thalidomide Thalidomide | [1] Thalidomide Thalidomide; | [1] TNF TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [20] 2 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
38 |
Melarsoprol
💬
| [1] Melarsoprol Melarsoprol | [1] Melarsoprol Melarsoprol; | - | - | [1] 65 65 💬 |
39 |
Nifurtimox
💬
| [1] Nifurtimox Nifurtimox | [1] Nifurtimox Nifurtimox; | - | - | [1] 65 65 💬 |
40 |
Estradiol valerate
💬
| [1] Estradiol valerate Estradiol valerate | [1] Estradiol valerate Estradiol valerate; | [2] ESR1 ESR1, ESR2 💬 | [10] Breast cancer Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬 | [1] 65 65 💬 |
41 |
Zoledronic acid
💬
| [1] Zoledronic acid Zoledronic acid | [4] ACLASTA ACLASTA; Zoledronate; Zoledronic acid; Zometa; | [1] FDPS FDPS 💬 | [4] Human T-cell leukemia virus 1 infection Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [13] 5 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
42 |
Benznidazole
💬
| [1] Benznidazole Benznidazole | [1] Benznidazole Benznidazole; | - | - | [1] 65 65 💬 |
43 |
Rifaximin
💬
| [1] Rifaximin Rifaximin | [3] Rifaximin Rifaximin; RIFAXIMINA; Xifaxan; | - | - | [9] 6 6, 65, 93, 94, 96, 97, 99, 296, 299 💬 |
44 |
Posaconazole
💬
| [1] Posaconazole Posaconazole | [2] Noxafil Noxafil; Posaconazole; | - | - | [3] 60 60, 65, 299 💬 |
45 |
Infliximab
💬
| [1] Infliximab Infliximab | [6] Flixabi Flixabi; Inflectra; Infliximab; REMICADE; REMSIMA; Zessly; | [1] TNF TNF 💬 | [67] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [27] 35 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
46 |
Alefacept
💬
| [1] Alefacept Alefacept | [1] Alefacept Alefacept; | [1] CD58 CD58 💬 | [2] Cell adhesion molecules Cell adhesion molecules, Epstein-Barr virus infection 💬 | [6] 37 37, 60, 65, 164, 284, 285 💬 |
47 |
Alemtuzumab
💬
| [1] Alemtuzumab Alemtuzumab | [4] Alemtuzumab Alemtuzumab; Campath; Lemtrada; MABCAMPATH; | [1] CD52 CD52 💬 | [1] 💬 | [22] 13 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬 |
48 |
Anakinra
💬
| [1] Anakinra Anakinra | [2] Anakinra Anakinra; Kineret; | [2] IL1R1 IL1R1, IL1R2 💬 | [15] Amoebiasis Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬 | [18] 2 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
49 |
Arginine
💬
| [1] Arginine Arginine | [6] Arginina Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; | - | - | [12] 46 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299 💬 |
50 |
Rituximab
💬
| [1] Rituximab Rituximab | [6] MabThera MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; Truxima; | [1] MS4A1 MS4A1 💬 | [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [48] 11 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
51 |
Abatacept
💬
| [1] Abatacept Abatacept | [2] ABATACEPT ABATACEPT; Orencia; | [2] CD80 CD80, CD86 💬 | [13] Allograft rejection Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬 | [26] 11 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
52 |
Filgrastim
💬
| [1] Filgrastim Filgrastim | [7] Filgrastim Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio; | [1] CSF3R CSF3R 💬 | [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [35] 2 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
53 |
Lenograstim
💬
| [1] Lenograstim Lenograstim | [2] G-CSF G-CSF; Lenograstim; | [1] CSF3R CSF3R 💬 | [5] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [7] 2 2, 13, 16, 18, 19, 57, 65 💬 |
54 |
Mecasermin
💬
| [1] Mecasermin Mecasermin | [3] Increlex Increlex; MECASERMIN; MECASERMINA; | [2] GHR GHR, IGF1R 💬 | [33] AMPK signaling pathway AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬 | [6] 65 65, 78, 96, 168, 265, 299 💬 |
55 |
Polyethylene glycol 3350
💬
| [1] Polyethylene glycol Polyethylene glycol | [4] Macrogol Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350; | - | - | [7] 6 6, 78, 96, 97, 235, 276, 299 💬 |
56 |
Daclizumab
💬
| [1] Daclizumab Daclizumab | [3] DACLIZUMAB DACLIZUMAB; Zenapax; Zinbryta; | [1] IL2RA IL2RA 💬 | [11] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬 | [8] 13 13, 56, 60, 65, 97, 107, 283, 284 💬 |
57 |
Doxorubicin
💬
| [1] Doxorubicin Doxorubicin | [2] Doxorubicin Doxorubicin; Doxorubicin Hydrochloride; | [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [5] 26 26, 28, 34, 65, 331 💬 |
58 |
Hyaluronidase
💬
| [1] Hyaluronidase Hyaluronidase | [2] Hyaluronidase Hyaluronidase; Hyaluronoglucosaminidase; | - | - | [5] 14 14, 28, 51, 65, 331 💬 |
59 |
Hyaluronidase
💬
| [1] Hyaluronidase Hyaluronidase | [2] Hyaluronidase Hyaluronidase; Hyaluronoglucosaminidase; | - | - | [5] 14 14, 28, 51, 65, 331 💬 |
60 |
Mercaptopurine
💬
| [1] Mercaptopurine Mercaptopurine | [4] 6-Mercaptopurine 6-Mercaptopurine; 6-MP; MERCAPTOPURINE; PURINETHOL; | [1] HPRT1 HPRT1 💬 | [4] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [4] 65 65, 96, 97, 164 💬 |
61 |
Metformin
💬
| [1] Metformin Metformin | [5] Metformin Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine; | [2] PRKAA1 PRKAA1, PRKAA2 💬 | [20] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬 | [25] 2 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 |
62 |
Mycophenolic acid
💬
| [1] Mycophenolic acid Mycophenolic acid | [5] Acido Micofenolico Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic Acid; Myfortic; | [2] IMPDH1 IMPDH1, IMPDH2 💬 | [4] Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [36] 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
63 |
Omalizumab
💬
| [1] Omalizumab Omalizumab | [2] Omalizumab Omalizumab; XOLAIR; | [1] FCER1A FCER1A 💬 | [4] Asthma Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬 | [7] 46 46, 53, 65, 98, 162, 226, 299 💬 |
64 |
Palifermin
💬
| [1] Palifermin Palifermin | [2] Kepivance Kepivance; Palifermin; | [1] FGFR2 FGFR2 💬 | [13] Calcium signaling pathway Calcium signaling pathway, Central carbon metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Gastric cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells 💬 | [5] 13 13, 36, 38, 39, 65 💬 |
65 |
Pantoprazole
💬
| [1] Pantoprazole Pantoprazole | [1] PANTOPRAZOLE PANTOPRAZOLE; | [2] ATP4A ATP4A, ATP4B 💬 | [4] Collecting duct acid secretion Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬 | [2] 13 13, 65 💬 |
66 |
Parathyroid hormone
💬
| [1] Parathyroid hormone Parathyroid hormone | [5] Natpar Natpar; Natpara; PARATHYROID HORMONE; PREOTACT; RhPTH; | [2] PTH1R PTH1R, PTH2R 💬 | [3] Endocrine and other factor-regulated calcium reabsorption Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬 | [3] 70 70, 235, 326 💬 |
67 |
Pegademase bovine
💬
| [1] Pegademase Pegademase | [1] Adagen Adagen; | - | - | [1] 65 65 💬 |
68 |
Teriparatide
💬
| [1] Teriparatide Teriparatide | [4] Forsteo Forsteo; Forteo; PTH 1-34; Teriparatide; | [1] PTH1R PTH1R 💬 | [3] Endocrine and other factor-regulated calcium reabsorption Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬 | [7] 46 46, 65, 68, 70, 71, 235, 274 💬 |
69 |
Thymalfasin
💬
| [1] Thymalfasin Thymalfasin | [1] THYMALFASIN THYMALFASIN; | - | - | [1] 65 65 💬 |
70 |
Hyaluronidase
💬
| [1] Hyaluronidase Hyaluronidase | [2] HYALURONIDASE HYALURONIDASE; Hyaluronoglucosaminidase; | - | - | [5] 14 14, 28, 51, 65, 331 💬 |
71 |
Treosulfan
💬
| [1] Treosulfan Treosulfan | [2] OVASTAT OVASTAT; TREOSULFAN; | - | - | [6] 13 13, 19, 62, 65, 283, 286 💬 |
72 |
Cyclophosphamide
💬
| [1] Cyclophosphamide Cyclophosphamide | [6] Ciclofosfamida Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan; | - | - | [44] 11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬 |
73 |
Daunorubicin
💬
| [1] Daunorubicin Daunorubicin | [1] Daunorubicin Daunorubicin; | [2] TOP2A TOP2A, TOP2B 💬 | [1] Platinum drug resistance Platinum drug resistance 💬 | [1] 65 65 💬 |
74 |
Eflornithine
💬
| [1] Eflornithine Eflornithine | [1] Eflornithine Eflornithine; | [1] ODC1 ODC1 💬 | [3] Arginine and proline metabolism Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways 💬 | [1] 65 65 💬 |
75 |
Fludarabine
💬
| [1] Fludarabine Fludarabine | [4] FLUDARA FLUDARA; FLUDARABINA; Fludarabine; Fludarabine Phosphate; | [1] RRM1 RRM1 💬 | [6] Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬 | [20] 11 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
76 |
Pentamidine
💬
| [1] Pentamidine Pentamidine | [2] Pentamidina Pentamidina; Pentamidine; | - | - | [2] 61 61, 65 💬 |
77 |
Phenindione
💬
| [1] Phenindione Phenindione | [0] | [1] VKORC1 VKORC1 💬 | [3] Biosynthesis of cofactors Biosynthesis of cofactors, Metabolic pathways, Ubiquinone and other terpenoid-quinone biosynthesis 💬 | - |
78 |
Pioglitazone
💬
| [1] Pioglitazone Pioglitazone | [1] Pioglitazone Pioglitazone; | [1] PPARG PPARG 💬 | [11] AMPK signaling pathway AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬 | [17] 2 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
79 |
Procarbazine
💬
| [1] Procarbazine Procarbazine | [1] Procarbazine Procarbazine; | - | - | [1] 65 65 💬 |
80 |
Tacrolimus
💬
| [1] Tacrolimus Tacrolimus | [2] Prograf Prograf; Tacrolimus; | [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [34] 2 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
81 |
Valaciclovir
💬
| [1] Valaciclovir Valaciclovir | [1] Valacyclovir Valacyclovir; | - | - | [1] 65 65 💬 |
82 |
Vinblastine
💬
| [1] Vinblastine Vinblastine | [2] Vinblastine Vinblastine; Vinblastine sulfate; | [9] TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | [10] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | [2] 34 34, 65 💬 |
83 |
Vincristine
💬
| [1] Vincristine Vincristine | [2] Vincristine Vincristine; Vincristine Sulfate; | [9] TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | [10] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | [4] 26 26, 34, 65, 331 💬 |
84 |
Zoledronic acid
💬
| [1] Zoledronic acid Zoledronic acid | [4] ACLASTA ACLASTA; Zoledronate; Zoledronic acid; Zometa; | [1] FDPS FDPS 💬 | [4] Human T-cell leukemia virus 1 infection Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [13] 5 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
85 |
Plerixafor
💬
| [1] Plerixafor Plerixafor | [2] Mozobil Mozobil; Plerixafor; | [1] CXCR4 CXCR4 💬 | [14] Axon guidance Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬 | [5] 19 19, 20, 65, 285, 299 💬 |
86 |
Romiplostim
💬
| [1] Romiplostim Romiplostim | [2] NPLATE NPLATE; Romiplostim; | [1] MPL MPL 💬 | [2] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬 | [4] 60 60, 63, 64, 65 💬 |
87 |
Ustekinumab
💬
| [1] Ustekinumab Ustekinumab | [2] Stelara Stelara; Ustekinumab; | [3] IL12A IL12A, IL12B, IL23A 💬 | [28] African trypanosomiasis African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬 | [16] 37 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
88 |
Ruxolitinib
💬
| [1] Ruxolitinib Ruxolitinib | [1] Ruxolitinib Ruxolitinib; | [2] JAK1 JAK1, JAK2 💬 | [35] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬 | [3] 60 60, 65, 228 💬 |
89 |
Tofacitinib
💬
| [1] Tofacitinib Tofacitinib | [4] Tasocitinib Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR; | [4] JAK1 JAK1, JAK2, JAK3, TYK2 💬 | [37] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬 | [15] 11 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
90 |
Empagliflozin
💬
| [1] Empagliflozin Empagliflozin | [2] Empagliflozin Empagliflozin; Jardiance; | [1] SLC5A2 SLC5A2 💬 | [1] 💬 | [6] 58 58, 65, 67, 72, 97, 257 💬 |
91 |
Valaciclovir hydrochloride hydrate
💬
| [1] Valaciclovir Valaciclovir | [1] Valacyclovir Valacyclovir; | - | - | [1] 65 65 💬 |
92 |
Emapalumab
💬
| [1] Emapalumab Emapalumab | [1] Emapalumab Emapalumab; | [1] IFNG IFNG 💬 | [32] African trypanosomiasis African trypanosomiasis, Allograft rejection, Amoebiasis, Antigen processing and presentation, Chagas disease, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hepatitis C, Herpes simplex virus 1 infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Leishmaniasis, Malaria, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Proteasome, Rheumatoid arthritis, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬 | [3] 49 49, 65, 107 💬 |
93 |
Tabelecleucel
💬
| [1] Tabelecleucel Tabelecleucel | [1] Tabelecleucel Tabelecleucel; | - | - | [1] 65 65 💬 |
94 |
Leniolisib
💬
| [1] Leniolisib Leniolisib | [1] Leniolisib Leniolisib; | [3] PIK3CA PIK3CA, PIK3CB, PIK3CD 💬 | [106] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬 | [2] 53 53, 65 💬 |
95 |
Rimiducid
💬
| [1] Rimiducid Rimiducid | [1] Rimiducid Rimiducid; | [1] CASP9 CASP9 💬 | [35] Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬 | [6] 19 19, 60, 65, 284, 285, 326 💬 |
96 |
Fexinidazole
💬
| [1] Fexinidazole Fexinidazole | [1] Fexinidazole Fexinidazole; | - | - | [1] 65 65 💬 |
97 |
Triheptanoin
💬
| [1] Triheptanoin Triheptanoin | [1] TRIHEPTANOIN TRIHEPTANOIN; | - | - | [10] 2 2, 8, 65, 149, 156, 248, 256, 257, 317, 324 💬 |
98 |
Monomethyl fumarate
💬
| [1] Monomethyl fumarate Monomethyl fumarate | [2] Bafiertam Bafiertam; Monomethyl fumarate; | - | - | [1] 13 13 💬 |
99 |
Elasomeran
💬
| [1] Moderna COVID-19 Vaccine Moderna COVID-19 Vaccine | [4] COVID-19 Vaccine Moderna COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax; | - | - | [5] 13 13, 46, 51, 65, 299 💬 |