Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Proline 💬[1] Proline[1] Proline--[2] 94, 97 💬
2 Tretinoin 💬[1] Tretinoin[5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[3] PML,
RARA,
RARB 💬 		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231 💬
3 Hymecromone 💬[1] Hymecromone[1] Hymecromone--[1] 94 💬
4 Mitomycin 💬[1] Mitomycin[2] Mitomycin; Mitomycin C--[2] 94, 329 💬
5 Vancomycin 💬[1] Vancomycin[1] Vancomycin--[8] 13, 46, 70, 94, 96, 97, 296, 299 💬
6 Acetylcysteine 💬[1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-acetylcysteine--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
7 Azathioprine 💬[1] Azathioprine[3] Azathioprine; Azatioprina; Imuran--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
8 Budesonide 💬[1] Budesonide[4] Budesonide; Entocort; Jorveza; Symbicort[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
9 Metronidazole 💬[1] Metronidazole[3] Flagyl; Metronidazol; Metronidazole--[7] 46, 51, 63, 94, 96, 97, 291 💬
10 Zidovudine 💬[1] Zidovudine[3] COMBIVIR; Retrovir; Zidovudine--[6] 25, 26, 135, 265, 325, 331 💬
11 Simvastatin 💬[1] Simvastatin[3] Simvastatin; Simvastatina; Simvastatine[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
12 Sulfasalazine 💬[1] Sulfasalazine[3] Salazosulfapyridine; Salicylazosulfapyridine; SULFASALAZINE--[6] 46, 86, 94, 107, 270, 271 💬
13 Fenofibrate 💬[1] Fenofibrate[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
14 Ursodiol 💬[1] Ursodeoxycholic acid[4] UDCA; URSODEOXYCHOLIC ACID; Ursodiol; UrsoFalk[1] NR1H4 💬 [1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
15 Thalidomide 💬[1] Thalidomide[1] Thalidomide[1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
16 Bezafibrate 💬[1] Bezafibrate[1] BEZAFIBRATE[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324 💬
17 Cladribine 💬[1] Cladribine[4] 2-CdA; CLADRIBINA; Cladribine; MAVENCLAD[1] RRM1 💬 [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 11, 13, 94 💬
18 Mizoribine 💬[1] Mizoribine[2] BREDININ; Mizoribine[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[8] 46, 49, 51, 53, 66, 94, 222, 224 💬
19 Rifaximin 💬[1] Rifaximin[3] Rifaximin; RIFAXIMINA; Xifaxan--[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
20 Rituximab 💬[1] Rituximab[6] MABTHERA; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
21 Minocycline 💬[1] Minocycline[3] Minocycline; Minocycline Hydrochloride; Minomycin--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
22 Erlotinib 💬[1] Erlotinib[1] Erlotinib[1] EGFR 💬 [48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[1] 94 💬
23 Vedolizumab 💬[1] Vedolizumab[2] ENTYVIO; VEDOLIZUMAB[2] ITGA4,
ITGB7 💬 		[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[3] 94, 96, 97 💬
24 Potassium 💬[1] Potassium[1] Potassium--[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
25 Cenicriviroc 💬[1] Cenicriviroc[1] Cenicriviroc[2] CCR2,
CCR5 💬 		[11] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[1] 94 💬
26 Volixibat 💬[1] Volixibat[1] Volixibat--[2] 93, 94 💬
27 Elafibranor 💬[1] Elafibranor[1] Elafibranor[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
28 Seladelpar 💬[1] Seladelpar[1] SELADELPAR[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬