156. レット症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 44 / 薬物数 : 61 - (DrugBank : 23) / 標的遺伝子数 : 57 - 標的パスウェイ数 : 83
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
ANA001XHCl (Syntagon) or VEXA-04 (Patheon)
Anavex Germany GmbH
2020 Phase 2 EUCTR2019-004345-32-GB Australia;United Kingdom;
ANAVEX2-73
Anavex Life Sciences Corp.
2019 Phase 3 NCT03941444 Australia;United Kingdom;
2019 Phase 2 NCT03758924 United States;
ANAVEX2-73 (blarcamesine)
Anavex Germany GmbH
2020 Phase 2 EUCTR2019-004345-32-GB Australia;United Kingdom;
ANAVEX2-73 oral liquid
Anavex Life Sciences Corp.
2020 Phase 2/Phase 3 NCT04304482 Australia;Canada;
Administration of a high dose of desipramine
Assistance Publique Hopitaux De Marseille
2009 Phase 2 NCT00990691 France;
Administration of a low dose of desipramine
Assistance Publique Hopitaux De Marseille
2009 Phase 2 NCT00990691 France;
Alpha-tocotrienol quinone
EDISON PHARMACEUTICALS INC.
2013 - EUCTR2012-005021-76-IT Italy;
CBD - Oral Solution, is known as Epidyolex, and is the approved name
GW Research Ltd
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
CBD - Solution Orale, conosciuto come Epidiolex, questo è il nome approvato negli Stati Uniti
GW RESEARCH LTD.
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
CBD Oral solution, is known as Epidyolex and is the approved name in the EU
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
CBD soluzione orale nota come Epidyolex e con tale nome è stato approvato in UE
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
Cannabidiol
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
Cannabidiol (CBD)
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
Cannabidiolo
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
Cannabidiolo (CBD)
GW RESEARCH LTD.
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
Creatine monohydrate
Medical University of Vienna
2005 - NCT01147575 Austria;
Dextromethorphan
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004 Phase 3 NCT00069550 United States;
1995 - NCT00004807 -
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
2012 Phase 2 NCT01520363 United States;
2004 Phase 2 NCT00593957 United States;
Kennedy Krieger Inst. Johns Hopkins Medicine
- Phase 2 EUCTR2008-005571-10-NO Norway;
Donepezil
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1995 - NCT00004807 -
Donepezil hydrochloride
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004 Phase 3 NCT00069550 United States;
EMD 128130
Newron Pharmaceuticals S.p.A.
2016 Phase 2 EUCTR2015-004448-20-GB Australia;India;Italy;United Kingdom;United States;
EPI-743
EDISON PHARMACEUTICALS INC.
2013 - EUCTR2012-005021-76-IT Italy;
Edison Pharmaceuticals Inc
2013 Phase 2 NCT01822249 Italy;
Epidyolex and is the approved name in the EU
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
Fingolimod (FTY720)
University Hospital, Basel, Switzerland
2013 Phase 1/Phase 2 NCT02061137 Switzerland;
GWP42003-P
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
GW Research Ltd
2020 Phase 3 NCT04252586 Australia;Canada;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 NCT03848832 Italy;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
Glatiramer Acetate
Montefiore Medical Center
2013 Phase 2 NCT02153723 United States;
Glatiramer Acetate (Copaxone®)
Sheba Medical Center
2014 Phase 1 NCT02023424 Israel;
Ketamine
Rett Syndrome Research Trust
2019 Phase 2 NCT03633058 United States;
Lovastatin
Montefiore Medical Center
2015 Phase 2 NCT02563860 United States;
NNZ-2566
Neuren Pharmaceuticals Limited
2016 Phase 2 NCT02715115 United States;
2013 Phase 2 NCT01703533 United States;
Probiotic-Lactobacillus plantarum PS128
National Taiwan University Hospital
2017 - NCT03259971 Taiwan;
Recombinant Human Insulin Growth Factor 1 (rhIGF-1)
Boston Children's Hospital
2013 Phase 2 NCT01777542 United States;
Rett-T
Anagnostou, Evdokia, M.D.
2019 Phase 2 NCT04041713 Canada;
RhIGF-1
Boston Children’s Hospital
2010 Phase 1 NCT01253317 United States;
Risperidone
Janssen-Ortho Inc., Canada
1999 Phase 3 NCT00261508 -
Sarizotan
Newron Pharmaceuticals SPA
2016 Phase 2/Phase 3 NCT02790034 Australia;India;Italy;United Kingdom;United States;
Topiramate
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1995 - NCT00004807 -
Tridecanoic Acid
Sheba Medical Center
2017 Phase 2 NCT03059160 -
Triheptanoin
Center for Rare Neurological Diseases, Norcross, GA
2016 Phase 2 NCT02696044 United States;
Trofinetide
ACADIA Pharmaceuticals Inc.
2021 Phase 2/Phase 3 NCT04988867 United States;
2020 Phase 3 NCT04776746 United States;
2020 Phase 3 NCT04279314 United States;
2019 Phase 3 NCT04181723 United States;
Anavex Germany GmbH
2020 Phase 2 EUCTR2019-004345-32-GB Australia;United Kingdom;
ANAVEX2-73
Anavex Life Sciences Corp.
2019 Phase 3 NCT03941444 Australia;United Kingdom;
2019 Phase 2 NCT03758924 United States;
ANAVEX2-73 (blarcamesine)
Anavex Germany GmbH
2020 Phase 2 EUCTR2019-004345-32-GB Australia;United Kingdom;
ANAVEX2-73 oral liquid
Anavex Life Sciences Corp.
2020 Phase 2/Phase 3 NCT04304482 Australia;Canada;
Administration of a high dose of desipramine
Assistance Publique Hopitaux De Marseille
2009 Phase 2 NCT00990691 France;
Administration of a low dose of desipramine
Assistance Publique Hopitaux De Marseille
2009 Phase 2 NCT00990691 France;
Alpha-tocotrienol quinone
EDISON PHARMACEUTICALS INC.
2013 - EUCTR2012-005021-76-IT Italy;
CBD - Oral Solution, is known as Epidyolex, and is the approved name
GW Research Ltd
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
CBD - Solution Orale, conosciuto come Epidiolex, questo è il nome approvato negli Stati Uniti
GW RESEARCH LTD.
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
CBD Oral solution, is known as Epidyolex and is the approved name in the EU
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
CBD soluzione orale nota come Epidyolex e con tale nome è stato approvato in UE
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
Cannabidiol
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
Cannabidiol (CBD)
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
Cannabidiolo
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
Cannabidiolo (CBD)
GW RESEARCH LTD.
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
Creatine monohydrate
Medical University of Vienna
2005 - NCT01147575 Austria;
Dextromethorphan
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004 Phase 3 NCT00069550 United States;
1995 - NCT00004807 -
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
2012 Phase 2 NCT01520363 United States;
2004 Phase 2 NCT00593957 United States;
Kennedy Krieger Inst. Johns Hopkins Medicine
- Phase 2 EUCTR2008-005571-10-NO Norway;
Donepezil
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1995 - NCT00004807 -
Donepezil hydrochloride
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004 Phase 3 NCT00069550 United States;
EMD 128130
Newron Pharmaceuticals S.p.A.
2016 Phase 2 EUCTR2015-004448-20-GB Australia;India;Italy;United Kingdom;United States;
EPI-743
EDISON PHARMACEUTICALS INC.
2013 - EUCTR2012-005021-76-IT Italy;
Edison Pharmaceuticals Inc
2013 Phase 2 NCT01822249 Italy;
Epidyolex and is the approved name in the EU
GW Research Ltd
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
Fingolimod (FTY720)
University Hospital, Basel, Switzerland
2013 Phase 1/Phase 2 NCT02061137 Switzerland;
GWP42003-P
GW RESEARCH LTD.
2020 Phase 3 EUCTR2019-001605-24-IT Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003370-27-IT Canada;Germany;Italy;Spain;United Kingdom;United States;
GW Research Ltd
2020 Phase 3 NCT04252586 Australia;Canada;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001605-24-ES Australia;Canada;Italy;Spain;United Kingdom;United States;
2019 Phase 3 NCT03848832 Italy;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-003370-27-GB Australia;Canada;France;Italy;Spain;United Kingdom;United States;
Glatiramer Acetate
Montefiore Medical Center
2013 Phase 2 NCT02153723 United States;
Glatiramer Acetate (Copaxone®)
Sheba Medical Center
2014 Phase 1 NCT02023424 Israel;
Ketamine
Rett Syndrome Research Trust
2019 Phase 2 NCT03633058 United States;
Lovastatin
Montefiore Medical Center
2015 Phase 2 NCT02563860 United States;
NNZ-2566
Neuren Pharmaceuticals Limited
2016 Phase 2 NCT02715115 United States;
2013 Phase 2 NCT01703533 United States;
Probiotic-Lactobacillus plantarum PS128
National Taiwan University Hospital
2017 - NCT03259971 Taiwan;
Recombinant Human Insulin Growth Factor 1 (rhIGF-1)
Boston Children's Hospital
2013 Phase 2 NCT01777542 United States;
Rett-T
Anagnostou, Evdokia, M.D.
2019 Phase 2 NCT04041713 Canada;
RhIGF-1
Boston Children’s Hospital
2010 Phase 1 NCT01253317 United States;
Risperidone
Janssen-Ortho Inc., Canada
1999 Phase 3 NCT00261508 -
Sarizotan
Newron Pharmaceuticals SPA
2016 Phase 2/Phase 3 NCT02790034 Australia;India;Italy;United Kingdom;United States;
Topiramate
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1995 - NCT00004807 -
Tridecanoic Acid
Sheba Medical Center
2017 Phase 2 NCT03059160 -
Triheptanoin
Center for Rare Neurological Diseases, Norcross, GA
2016 Phase 2 NCT02696044 United States;
Trofinetide
ACADIA Pharmaceuticals Inc.
2021 Phase 2/Phase 3 NCT04988867 United States;
2020 Phase 3 NCT04776746 United States;
2020 Phase 3 NCT04279314 United States;
2019 Phase 3 NCT04181723 United States;