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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ACE I, ATA II and Statins----1件: 218
2ACE-inhibitor----1件: 218
3AT1-inhibitor----1件: 218
4ATRASENTAN1件: Atrasentan---3件: 66, 218, 222
5Bardoxolone1件: Bardoxolone1件: D09584 --7件: 66, 67, 84, 85, 86, 218, 222
6Bardoxolone methyl2件: Bardoxolone,
Bardoxolone methyl		2件: D09584 ,
D09585 		--7件: 66, 67, 84, 85, 86, 218, 222
7Benazepril1件: Benazepril1件: D07499 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 49, 57, 218, 224
8Benazepril hydrochloride 10 milligram (mg) Tab1件: Benazepril1件: D07499 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 218
9Benazepril, Valsartan and Fluvastatin3件: Benazepril,
Fluvastatin,
Valsartan		3件: D00400 ,
D07499 ,
D07983 		3件: ACE,
AGTR1,
HMGCR 💬		22件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Bile secretion, Calcium signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Terpenoid backbone biosynthesis, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 218
10Delix----1件: 218
11ELX-021件: ELX-02---3件: 19, 218, 299
12Fluvastatin1件: Fluvastatin1件: D07983 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 79, 218, 222
13Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
14HMG-Coenzyme inhibitor (statin)----1件: 218
15Hydroxychloroquine1件: Hydroxychloroquine1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
16Hydroxychloroquine Sulfate 100 milligram (mg) Tab2件: Hydroxychloroquine,
Sulfate ion		1件: D08050 --1件: 218
17Lademirsen----1件: 218
18Lademirsen (SAR339375)----1件: 218
19Metformin1件: Metformin1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
20Paricalcitol1件: Paricalcitol1件: D00930 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298
21R3R01----2件: 218, 222
22Ramipril1件: Ramipril1件: D00421 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257
23RE-021----3件: 66, 218, 222
24RG-012----1件: 218
25RG012----1件: 218
26RTA 402----3件: 67, 86, 218
27SAR339375----1件: 218
28SGLT2 inhibitor----1件: 218
29SPARSENTAN1件: Sparsentan1件: D11776 2件: AGTR1,
EDNRA 💬		17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222
30Spironolactone1件: Spironolactone1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225
31Sulfate1件: Sulfate ion---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
32Valsartan1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224