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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
118F-AV-1451----3件: 5, 7, 127
218F-FDG1件: Fludeoxyglucose (18F)---8件: 5, 6, 7, 13, 84, 85, 127, 300
318F-RO6958948----3件: 5, 7, 127
44-benzyl-2-naphtalen-1-yl-1,2,4-thiadiazolidine-3,5-dione----1件: 5
59-CIS, 12-CIS-11,11-D2-LINOLEIC ACID ETHYL ESTER1件: Linoleic acid---2件: 2, 5
6[18F]-PI2620----1件: 5
7[18F]Florbetapir----1件: 5
8[18F]MNI-815 (MNI-815)----1件: 5
9[18F]MNI-952----1件: 5
10[18F]MNI-958----1件: 5
11[18F]T807 ([18F]MNI-777)----2件: 5, 6
12[F18]-FDDNP----1件: 5
13AB1010----6件: 2, 5, 6, 13, 46, 96
14ABBV-8E12----2件: 5, 7
15AL----11件: 5, 6, 7, 13, 28, 51, 67, 86, 97, 114, 127
16AL-108----1件: 5
17Alpha-lipoic acid and L-acetyl carnitine2件: Levocarnitine,
Lipoic acid
1件: D02176 --1件: 5
18Anti-Parkinson medication----5件: 5, 6, 7, 8, 17
19Antisense oligonucleotide----1件: 5
20Apomorphine1件: Apomorphine1件: D07460 2件: DRD1,
DRD2 💬
11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
21ASK Nr. 21972----1件: 5
22Azilect1件: Rasagiline2件: D08469 ,
D10829
1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬4件: 2, 5, 6, 17
23AZP2006 oral solution----1件: 5
24Bepranemab----1件: 5
25BIIB092----3件: 5, 7, 127
26BMS-9861681件: Gosuranemab1件: D11293 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 5
27BMS986168----1件: 5
28BOTULINUM TOXIN TYPE A1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬10件: 2, 5, 6, 7, 13, 15, 17, 70, 113, 149
29Carnitine1件: Levocarnitine1件: D02176 --9件: 5, 13, 58, 86, 96, 97, 265, 298, 316
30Coenzym Q10 Nanodispersion----1件: 5
31Coenzym Q10, Ubiquinon, Ubichinon----1件: 5
32Coenzyme Q101件: Ubidecarenone1件: D01065 --11件: 2, 5, 6, 8, 10, 18, 46, 57, 113, 214, 215
33CoQ10----3件: 5, 6, 8
34Creatine1件: Creatine---11件: 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
35DaTSCAN1件: Ioflupane I-123---3件: 2, 5, 6
36Davunetide1件: Davunetide1件: D09401 --3件: 5, 7, 127
37Davunetide (AL-108, NAP)1件: Davunetide1件: D09401 --3件: 5, 7, 127
38Donepezil1件: Donepezil1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
39Droxidopa1件: Droxidopa1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬
14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
40Emeramide1件: Emeramide---2件: 5, 17
41Example1件: Hydroxide ion---1件: 5
42Exelon 1,5 mg Hartkapseln1件: Rivastigmine1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬1件: 5
43Exelon 3,0 mg Hartkapseln1件: Rivastigmine1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬1件: 5
44Exelon 6,0 mg Hartkapseln1件: Rivastigmine1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬1件: 5
45F-18----2件: 5, 127
46F-18 AV 1451----2件: 5, 127
47Fasudil1件: Fasudil1件: D07941 2件: ROCK1,
ROCK2 💬
23件: Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 2, 5, 7, 51
48Flortaucipir1件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
49Flortaucipir F181件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
50Flutemetamol1件: Flutemetamol (18F)---4件: 5, 6, 7, 127
51Fresh Frozen Plasma----1件: 5
52GDNF & Synchro Med Infusion System----1件: 5
53Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
54Hydrogen1件: Hydrogen---6件: 5, 6, 17, 83, 97, 226
55Linoleic acid1件: Linoleic acid---4件: 2, 5, 13, 299
56Lipoic acid1件: Lipoic acid---5件: 2, 5, 13, 14, 20
57Lithium1件: Lithium citrate1件: D04749 --5件: 2, 5, 6, 7, 8
58MASITINIB1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
59Masitinib 100mg1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 2, 5
60Masitinib 200mg1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 2, 5
61MASITINIB MESYLATE1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
62N1,N3-BIS(2-MERCAPTOETHYL) ISOPHTHALAMIDE----2件: 5, 17
63NBMI----2件: 5, 17
64Niacinamide1件: Nicotinamide1件: D00036 --3件: 5, 6, 67
65Nitrogen1件: Nitrogen1件: D00083 --5件: 5, 6, 17, 211, 299
66NP031112----1件: 5
67NP031112 600mg----1件: 5
68NP031112 800mg----1件: 5
69NT 101----4件: 5, 6, 7, 17
70Placebo----28件: 3, 5, 6, 11, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
71Pyruvate, creatine, niacinamide2件: Creatine,
Nicotinamide
1件: D00036 --1件: 5
72Raclopride1件: Raclopride---4件: 5, 6, 7, 17
73Radiopharmaceuticals----1件: 5
74Rasagilin----2件: 5, 6
75Rasagiline1件: Rasagiline2件: D08469 ,
D10829
1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬4件: 2, 5, 6, 17
76RASAGILINE MESILATE1件: Rasagiline2件: D08469 ,
D10829
1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬3件: 2, 5, 6
77RILUZOLE1件: Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
78RIVASTIGMINE1件: Rivastigmine1件: D03822 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
79RT001----3件: 2, 5, 120
80Salsalate1件: Salsalate1件: D00428 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
81Single dose C2N-8E12----1件: 5
82Stem cell therapy----1件: 5
83Sugar pill----8件: 5, 6, 49, 67, 70, 86, 206, 210
84Suvorexant1件: Suvorexant1件: D10082 2件: HCRTR1,
HCRTR2 💬
1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13
85Tideglusib1件: Tideglusib---2件: 5, 113
86Tolfenamic Acid1件: Tolfenamic acid1件: D01183 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
87TPI 287----2件: 5, 7
88TPI 287 2 mg/m2----2件: 5, 7
89TPI-2871件: TPI-287---2件: 5, 7
90TPI-287 20 mg/m21件: TPI-287---2件: 5, 7
91TPI-287 6.3 mg/m21件: TPI-287---2件: 5, 7
92Trihexyphenidyl1件: Trihexyphenidyl1件: D08638 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
93Ubidecarenon----1件: 5
94UCB0107 (bepranemab)----1件: 5
95Valproic Acid1件: Valproic acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬
17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬7件: 3, 5, 26, 65, 90, 222, 256
96Vizamyl1件: Flutemetamol (18F)---3件: 5, 7, 127
97Vizamyl (flutemetamol(F-18))2件: Flutemetamol,
Flutemetamol (18F)
---3件: 5, 7, 127
98Water1件: Water1件: D00001 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
99Xeomin1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬7件: 5, 6, 7, 13, 15, 17, 113
100Zoledronic acid1件: Zoledronic acid2件: D01968 ,
D08689
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬12件: 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333
101Zoledronic Acid 5Mg/Bag 100Ml Inj1件: Zoledronic acid2件: D01968 ,
D08689
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 5, 6, 17
102Zolpidem1件: Zolpidem1件: D08690 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬
7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46