Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Atasol Drops USP 80mg/ml)		4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Allantoin
(Synonym: Optrex Eye Drops)		1件: ALLANTOIN1件: D00121 --1件: 36
3 alpha-Tocopherol acetate
(Synonym: Multi Vitamin Drops with Fluoride with Iron)		3件: Tocopherol acetate; TOCOPHERYL ACETATE; Vitamin E---2件: 49, 206
4 Amoxicillin
(Synonym: Amoxil Pediatric Drops Pws 50mg/ml)		4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin2件: D00229 ,
D07452 		--9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
5 Ascorbic acid
(Synonym: Children Vitamin Drops)		4件: Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
6 Betamethasone
(Synonym: Betnesol Eye and Ear Drops)		1件: Betamethasone1件: D00244 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235
7 Biotin
(Synonym: Quflora FE Pediatric Drops)		4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
8 Brimonidine
(Synonym: LUMIFY Redness Reliever Eye Drops)		2件: Brimonidine; Brimonidine tartrate1件: D07540 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬2件: 13, 90
9 Caffeine
(Synonym: SMITH BROS WILD CHERRY DAY TIME with Caffeine Soothing Drops)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
10 Chlorpheniramine
(Synonym: Neo DM DROPS DM)		1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
11 Chlorpromazine
(Synonym: Largactil Drops 40mg/ml)		2件: Chlorpromazine; Chlorpromazine Hydrochloride1件: D00270 13件: ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		22件: Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 254
12 Cholecalciferol
(Synonym: YYUX Organic Liquid Vitamin D3 Drops For Kids 4 plus years 600 IU)		5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D31件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬24件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
13 Cromoglicic acid
(Synonym: Anti-allergy Eye Drops)		4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium1件: D07753 --3件: 2, 85, 98
14 Cyanocobalamin
(Synonym: MultiVitamin with Fluoride Drops)		2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
15 Dextran
(Synonym: Walgreens Artificial Tears Lubricant Eye Drops)		1件: Dextran1件: D00060 --4件: 2, 62, 96, 97
16 Dextromethorphan
(Synonym: TRISPEC PSE Pediatric Drops Cough Suppressant Expectorant Nasal Decongestant GRAPE Flavor)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
17 Dorzolamide
(Synonym: Dorzolamide and Timolol Eye Drops BP)		1件: Dorzolamide1件: D07871 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
18 Ergocalciferol
(Synonym: Children Pediatric Vitamins Drops)		3件: Ergocalciferol; Vitamin D; Vitamin D21件: D00187 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬6件: 46, 49, 84, 96, 97, 299
19 Erythromycin
(Synonym: EryPed Drops)		1件: Erythromycin1件: D00140 --5件: 6, 36, 164, 228, 291
20 Ethanol
(Synonym: Nature Drops Hand Sanitizer)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
21 Ferrous sulfate anhydrous
(Synonym: Multi Vitamin Drops with Fluoride with Iron)		0件: ---1件: 46
22 Fluocinolone acetonide
(Synonym: Dermotic Oil Ear Drops)		2件: Fluocinolone Acetonide; Iluvien1件: D01825 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 90
23 Folic acid
(Synonym: Vigo Multivitamins Drops/lozenge)		5件: Acide folique; Folate; Folic Acid; Multivitamin; NICOTINAMIDE1件: D00070 --6件: 6, 41, 46, 49, 84, 296
24 Glycerin
(Synonym: Optimel Manuka Dry Eye Drops)		2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
25 Hyaluronic acid
(Synonym: Lubricant Eye Drops)		2件: Hyaluronate; Hyaluronic acid1件: D08043 --6件: 46, 53, 70, 97, 226, 231
26 Hydrocortisone
(Synonym: Oticin HC Ear Drops)		6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
27 Hydrocortisone acetate
(Synonym: Neo-cortef Eye Ear Drops Sterile Suspension)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
28 Ibuprofen
(Synonym: Advil Pediatric Drops Fever From Colds Or Flu)		2件: Ibuprofen; IBUPROFEN 200MG1件: D00126 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
29 Iron
(Synonym: NovaFerrum Pediatric Drops)		1件: Iron---6件: 18, 96, 97, 238, 254, 284
30 Levomefolic acid
(Synonym: Quflora Pediatric Drops)		1件: L-methylfolate1件: D09353 --2件: 6, 201
31 Lidocaine
(Synonym: Polysporin Plus Pain Relief Ear Drops)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
32 Magnesium oxide
(Synonym: Quflora Pediatric Drops)		1件: Magnesium oxide1件: D01167 --3件: 6, 166, 291
33 Mineral oil
(Synonym: Walgreens Lubricant Eye Drops Preservative Free)		1件: Paraffin Oil1件: D05042 --1件: 291
34 Morphine
(Synonym: Statex Drops 20mg/ml)		2件: Morphine; MORPHINE SULFATE1件: D08233 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 36, 46, 70, 85, 86
35 Neomycin
(Synonym: Neo-cortef Eye Ear Drops Sterile Suspension)		1件: Neomycin1件: D08260 --3件: 96, 97, 296
36 Niacin
(Synonym: Multi-Vitamin Fluoride and Iron Drops)		2件: Niacin; Nicotinic acid1件: D00049 --3件: 6, 78, 79
37 Nicotinamide
(Synonym: Vigo Multivitamins Drops/lozenge)		3件: Multivitamin; Niacinamide; Nicotinamide1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
38 Pectin
(Synonym: SMITH BROS WILD CHERRY Throat Drops)		1件: Pectin1件: D02316 --1件: 96
39 Phenylephrine
(Synonym: Virdec DM Drops)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
40 Propylene glycol
(Synonym: Topcare Health Lubricant Eye Drops)		1件: Propylene glycol1件: D00078 --1件: 51
41 Pseudoephedrine
(Synonym: Infants Tylenol Cold Suspension Drops)		1件: Pseudoephedrine1件: D08449 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
42 Pyridoxine
(Synonym: Infantol Drops)		2件: Pyridoxine; Vitamin B61件: D08454 --5件: 6, 93, 145, 206, 320
43 Riboflavin
(Synonym: Quflora FE Pediatric Drops)		2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
44 Salicylic acid
(Synonym: ClearSkinDays Acne Clearing Drops)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
45 Simethicone
(Synonym: Gerber Gas Relief Drops)		1件: Simethicone1件: D05841 --2件: 13, 96
46 Sodium fluoride
(Synonym: Pearl Drops Stainfighting Baking Soda Tpt)		1件: Sodium fluoride1件: D00943 --1件: 51
47 Thiamine
(Synonym: Infantol Drops)		2件: Thiamine; Vitamin B11件: D08580 --4件: 8, 93, 145, 265
48 Timolol
(Synonym: Dorzolamide and Timolol Eye Drops BP)		2件: Timolol; TIMOLOL MALEATE2件: D00378 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
49 Tocopherol
(Synonym: Multivitamin Drops with Fluoride)		2件: Tocoferol; Tocopherol1件: D02332 --6件: 13, 49, 90, 206, 257, 298
50 Vitamin A
(Synonym: Quflora FE Pediatric Drops)		1件: Vitamin A1件: D06543 2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬3件: 13, 53, 90
51 Vitamin D
(Synonym: Infantol Drops)		3件: Calciferol; Cod liver oil; Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
52 Vitamin E
(Synonym: NovaFerrum Multivitamin with Iron Pediatric Drops)		2件: Alpha-tocopherol; Vitamin E1件: D02331 --12件: 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
53 Zinc oxide
(Synonym: My Day Screen Medium Dark Tinted Drops SPF 30)		1件: Zinc oxide1件: D01170 --1件: 156