Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Acetaminophen 500 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Adenine
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		1件: Adenin1件: D00034 --1件: 46
3 Adenosine phosphate 0件: 1件: D02769 (Name: Adenosine phosphate)4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
4 Aluminium phosphate 1件: Aluminium phosphate---1件: 46
5 Betamethasone
(Synonym: Betamethasone Sodium Phosphate and Betamethasone Acetate)		1件: Betamethasone1件: D00244 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235
6 Caffeine
(Synonym: Acetaminophen 500 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
7 Carvedilol
(Synonym: Carvedilol Phosphate)		1件: Carvedilol1件: D00255 5件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		13件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 86, 113, 210
8 Chloroquine
(Synonym: Chloroquine Phosphate)		1件: Chloroquine1件: D02366 --3件: 46, 49, 95
9 Cipaglucosidase alfa
(Synonym: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate)		1件: Cipaglucosidase Alfa1件: D11798 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
10 Citric acid
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		1件: Citric acid1件: D01222 --2件: 53, 291
11 Clindamycin
(Synonym: Dalacin C Phosphate)		2件: CLINDAMYCIN; Dalacin C phosphate1件: D00277 --2件: 46, 299
12 D-glucose
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
13 Dexamethasone
(Synonym: Dexamethasone Sodium Phosphate)		5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
14 Dextrose, unspecified form
(Synonym: Anticoagulant Solution Citrate Phosphate Dextrose)		3件: Dextrose; Glucose; Smofkabiven---16件: 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299
15 Fludarabine
(Synonym: Fludarabine Phosphate)		4件: FLUDARA; FLUDARABINA; Fludarabine; Fludarabine phosphate1件: D07966 1件: RRM1 💬6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
16 Levomefolic acid
(Synonym: Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin)		1件: L-methylfolate1件: D09353 --2件: 6, 201
17 Mannitol
(Synonym: TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose Red Cell Preservative)		4件: Aridol; Bronchitol; Mannite; MANNITOL1件: D00062 --7件: 6, 13, 28, 60, 96, 113, 299
18 Mecobalamin
(Synonym: Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin)		2件: Mecobalamin; Methylcobalamin1件: D03246 --2件: 2, 70
19 Menadiol diphosphate
(Synonym: Menadiol phosphate)		1件: Menadiol Diphosphate1件: D08176 --1件: 299
20 Metformin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		5件: Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
21 Oseltamivir
(Synonym: Oseltamivir Phosphate)		1件: Oseltamivir1件: D08306 --2件: 97, 299
22 Phenylephrine
(Synonym: Promethazine Hydrochloride Phenylephrine Hydrochloride and Codeine Phosphate)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
23 Phosphate ion 1件: Phosphate---32件: 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
24 Phosphorus P-32
(Synonym: P32 Sodium Phosphate)		0件: ---1件: 37
25 Promethazine
(Synonym: Promethazine Hydrochloride and Codeine Phosphate)		1件: Promethazine1件: D00494 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 96
26 Pseudoephedrine
(Synonym: Codeine Phosphate and Pseudoephedrine Hydrochloride)		1件: Pseudoephedrine1件: D08449 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
27 Pyridoxal phosphate 0件: ---1件: 13
28 Riboflavin
(Synonym: Riboflavin 5 Phosphate Cap 50mg)		2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
29 Sitagliptin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		1件: Sitagliptin1件: D08516 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299
30 Sodium chloride
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; SPORANOX1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
31 Sodium citrate
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		1件: Sodium citrate2件: D01781 ,
D05855 		--4件: 67, 214, 215, 235
32 Sodium fluoride
(Synonym: All Solutions Acidulated Phosphate Fluoride Foam)		1件: Sodium fluoride1件: D00943 --1件: 51
33 Sodium glycerophosphate
(Synonym: Disodium glycerol phosphate)		1件: Smofkabiven1件: D10489 --1件: 66
34 Tretinoin
(Synonym: Clindamycin Phosphate and Tretinoin)		5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231