Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
2 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
3 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
4 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
5 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
6 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
7 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
8 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
9 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
10 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
11 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
12 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
13 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
14 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
15 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D08128 D08128 💬 |
Liothyronine | 013 4件: 13, 78, 210, 212 💬 |
16 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
17 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
18 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
19 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
20 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
21 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
22 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
23 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
THRA 2件: THRA, THRB 💬 |
D08128 D08128 💬 |
Liothyronine | 013 4件: 13, 78, 210, 212 💬 |
24 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
25 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |