Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Fluid shear stress and atherosclerosis 💬	1件: ACVR2A 💬	D09670 💬	Sotatercept	2件: 86, 284 💬
2	Fluid shear stress and atherosclerosis 💬	2件: ACVR2A, ACVR2B 💬	D10620 💬	Bimagrumab	1件: 15 💬
3	Fluid shear stress and atherosclerosis 💬	1件: ACVR2B 💬	D11701 💬	Luspatercept	1件: 60 💬
4	Fluid shear stress and atherosclerosis 💬	1件: BCL2 💬	D10679 💬	Venetoclax	1件: 28 💬
5	Fluid shear stress and atherosclerosis 💬	4件: CCL2, IL1A, IL1B, TNF 💬	D01583 💬	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
6	Fluid shear stress and atherosclerosis 💬	1件: HMOX1 💬	D05922 💬	Stannsoporfin	1件: 254 💬
7	Fluid shear stress and atherosclerosis 💬	1件: IFNG 💬	D11120 💬	Emapalumab	3件: 49, 65, 107 💬
8	Fluid shear stress and atherosclerosis 💬	1件: IFNG 💬	D04242 💬	Fontolizumab	1件: 46 💬
9	Fluid shear stress and atherosclerosis 💬	1件: IL1A 💬	D11253 💬	Bermekimab	1件: 51 💬
10	Fluid shear stress and atherosclerosis 💬	2件: IL1A, IL1B 💬	D06635 💬	Rilonacept	4件: 51, 106, 107, 266 💬

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