Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
2 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
3 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
4 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
5 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
6 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
7 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
8 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
9 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
10 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
11 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
12 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
13 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
14 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
CHRNA4 2件: CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 3件: 6 , 18, 53 💬 |
15 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
16 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRNA4 2件: CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 3件: 6 , 18, 53 💬 |
17 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
18 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIA2 6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
19 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
20 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
21 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
22 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
23 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
24 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
25 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
26 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
27 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
28 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
29 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
30 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
31 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
32 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
33 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
34 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
35 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
36 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
37 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
38 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
39 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
40 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
IFNGR1 1件: IFNGR1 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
41 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
42 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
43 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
44 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
45 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
46 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
47 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
48 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
49 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
50 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
51 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CHRNA4 2件: CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 3件: 6 , 18, 53 💬 |
52 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
53 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
54 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
55 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
56 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
CHRNA4 2件: CHRNA4, CHRNB2 💬 |
D08669 D08669 💬 |
Varenicline | 006 3件: 6 , 18, 53 💬 |
57 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
58 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
59 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
60 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
61 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
62 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
63 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
64 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
65 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
66 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
67 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
68 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
69 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
70 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
71 | Protein processing in endoplasmic reticulum 💬 Related to 3 target genes, 3 drugs (DrugBank) and 3 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
72 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
73 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
74 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
75 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
76 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
77 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D07704 D07704 💬 |
Citalopram | 006 7件: 6 , 8 , 13, 18, 46, 98, 127 💬 |
78 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 3件: 2 , 6 , 144 💬 |
79 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 2件: 2 , 6 💬 |
80 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
81 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
82 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07058 D07058 💬 |
Acamprosate | 006 2件: 6 , 206 💬 |
83 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07441 D07441 💬 |
Amantadine | 006 4件: 6 , 8 , 13, 127 💬 |
84 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
85 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D07283 D07283 💬 |
Esketamine | 002 3件: 2 , 4 , 70 💬 |
86 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08098 D08098 💬 |
Ketamine | 002 8件: 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
87 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 1件: 8 💬 |
88 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D08174 D08174 💬 |
Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
89 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
KCNC3 2件: KCNC3, KCND3 💬 |
D10228 D10228 💬 |
Amifampridine | 003 3件: 3 , 11, 12 💬 |
90 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
KCNC3 2件: KCNC3, KCND3 💬 |
D04127 D04127 💬 |
Dalfampridine | 003 5件: 3 , 4 , 6 , 13, 14 💬 |
91 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
KCND3 1件: KCND3 💬 |
D02910 D02910 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
92 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
93 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
94 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
95 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 1件: 13 💬 |
96 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
97 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
98 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
99 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PRKCB 1件: PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 1件: 168 💬 |
100 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 |
101 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D08880 D08880 💬 |
Carfilzomib | 028 1件: 28 💬 |
102 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D10130 D10130 💬 |
Ixazomib | 013 5件: 13, 16, 28, 51, 61 💬 |
103 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 2件: SLC6A2, SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
104 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D07704 D07704 💬 |
Citalopram | 006 7件: 6 , 8 , 13, 18, 46, 98, 127 💬 |
105 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
106 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 8件: 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
107 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
108 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
109 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
110 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
111 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
112 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
113 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
114 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 9件: 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |