Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD40 1件: CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 1件: 222 💬 |
| 2 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD40 1件: CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 2件: 49, 53 💬 |
| 3 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD40 1件: CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 2件: 53, 97 💬 |
| 4 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
| 5 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD86 1件: CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 1件: 46 💬 |
| 6 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CSF1R 3件: CSF1R, FLT1, FLT3 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 7 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CSF1R 2件: CSF1R, FLT3 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 1件: 34 💬 |
| 8 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CSF2 1件: CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 1件: 46 💬 |
| 9 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
ELANE 1件: ELANE 💬 |
D03788 D03788 💬 |
Sivelestat | 013 3件: 13, 85, 96 💬 |
| 10 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
FLT1 1件: FLT1 💬 |
D03218 D03218 💬 |
Axitinib | 034 1件: 34 💬 |
| 11 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
FLT1 1件: FLT1 💬 |
D08881 D08881 💬 |
Cediranib | 034 1件: 34 💬 |
| 12 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
FLT1 1件: FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
| 13 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
FLT3 1件: FLT3 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 14 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D08964 D08964 💬 |
Perampanel | 002 3件: 2 , 6 , 144 💬 |
| 15 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
| 16 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D02696 D02696 💬 |
Talampanel | 002 2件: 2 , 6 💬 |
| 17 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
| 18 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 2件: 75, 96 💬 |
| 19 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 20 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 21 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 22 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
| 23 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL2RB 1件: IL2RB 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
| 24 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 2件: 46, 96 💬 |
| 25 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 26 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬 |
| 27 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 2件: 28, 331 💬 |
| 28 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
| 29 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 2件: 96, 97 💬 |
| 30 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 2件: 96, 97 💬 |
| 31 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 3件: 94, 96, 97 💬 |
| 32 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
MET 1件: MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
| 33 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
| 34 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬 |
| 35 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
NGFR 1件: NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 2件: 53, 90 💬 |
| 36 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PML 2件: PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
| 37 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D12242 D12242 💬 |
Bocidelpar | 113 1件: 113 💬 |
| 38 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 1件: 20 💬 |
| 39 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
| 40 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
| 41 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 2件: 93, 94 💬 |
| 42 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 1件: 299 💬 |
| 43 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
| 44 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 2件: 26, 96 💬 |
| 45 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 1件: RARA 💬 |
D06543 D06543 💬 |
Vitamin A | 013 3件: 13, 53, 90 💬 |
| 46 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 4件: RARA, RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 1件: 37 💬 |
| 47 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RARA 4件: RARA, RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 1件: 49 💬 |
| 48 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
| 49 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
RXRA 3件: RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |