Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	CPS1	[6] Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, Metabol ...	D07130	Carglumic acid	[3] 245, 246, 251
2	ABAT	[7] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Al ...	D00399	Valproic acid	[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
3	ABAT	[7] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Al ...	D00535	Vigabatrin	[2] 145, 158
4	GAD1	[7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine me ...	D00399	Valproic acid	[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
5	GAD2	[7] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine me ...	D00399	Valproic acid	[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
6	ALDH5A1	[3] Alanine, aspartate and glutamate metabolism, Butanoate metabolism, Metabolic pathways	D00399	Valproic acid	[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256

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