Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	IL17F	[4] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Infl ...	D11550	Bimekizumab	[3] 46, 97, 271
2	IL31RA	[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway	D11080	Nemolizumab	[1] 51
3	IL17RA	[3] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Alcoholic liver disease	D10061	Brodalumab	[2] 37, 51
4	IDS	[3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome	D04499	Idursulfase	[1] 19
5	IDS	[3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome	D11025	Idursulfase beta	[1] 19
6	IDS	[3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome	D11812	Pabinafusp alfa	[1] 19
7	IDUA	[3] Glycosaminoglycan degradation, Metabolic pathways, Lysosome	D04670	Laronidase	[2] 19, 256
8	IFNA1	[25] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Toll-like rece ...	D09662	Rontalizumab	[1] 49
9	IFNA1	[25] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Toll-like rece ...	D09668	Sifalimumab	[1] 49
10	IFNA2	[25] Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Necroptosis, Toll-like rece ...	D09662	Rontalizumab	[1] 49

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