Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 NQO1 [7] Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D08682 Warfarin [11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
2 NCSTN [2] Notch signaling pathway, Alzheimer disease D09010 Tarenflurbil [1] 13
3 NR3C1 [1] Neuroactive ligand-receptor interaction D00088 Hydrocortisone [10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
4 NR3C1 [1] Neuroactive ligand-receptor interaction D00165 Hydrocortisone acetate [1] 97
5 NR3C1 [1] Neuroactive ligand-receptor interaction D00244 Betamethasone [8] 2, 28, 46, 65, 83, 90, 96, 235
6 NR3C1 [1] Neuroactive ligand-receptor interaction D00246 Budesonide [9] 66, 93, 94, 95, 96, 97, 98, 228, 299
7 NR3C1 [1] Neuroactive ligand-receptor interaction D00292 Dexamethasone [22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
8 NR3C1 [1] Neuroactive ligand-receptor interaction D00385 Triamcinolone [11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
9 NR3C1 [1] Neuroactive ligand-receptor interaction D00407 Methylprednisolone [46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
10 NR3C1 [1] Neuroactive ligand-receptor interaction D00472 Prednisolone [42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
11 NR3C1 [1] Neuroactive ligand-receptor interaction D00473 Prednisone [45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
12 NR3C1 [1] Neuroactive ligand-receptor interaction D00585 Mifepristone [1] 75
13 NR3C1 [1] Neuroactive ligand-receptor interaction D00689 Beclomethasone dipropionate [3] 85, 97, 98
14 NR3C1 [1] Neuroactive ligand-receptor interaction D00690 Mometasone furoate [2] 98, 162
15 NR3C1 [1] Neuroactive ligand-receptor interaction D00973 Cortisone acetate [1] 81
16 NR3C1 [1] Neuroactive ligand-receptor interaction D00976 Hydrocortisone cypionate [3] 6, 81, 83
17 NR3C1 [1] Neuroactive ligand-receptor interaction D00980 Prednisolone acetate [1] 222
18 NR3C1 [1] Neuroactive ligand-receptor interaction D01272 Clobetasol propionate [2] 46, 162
19 NR3C1 [1] Neuroactive ligand-receptor interaction D01442 Hydrocortisone succinate [3] 6, 81, 83
20 NR3C1 [1] Neuroactive ligand-receptor interaction D01703 Ciclesonide [1] 84
21 NR3C1 [1] Neuroactive ligand-receptor interaction D01708 Fluticasone propionate [2] 98, 228
22 NR3C1 [1] Neuroactive ligand-receptor interaction D01825 Fluocinolone acetonide [1] 90
23 NR3C1 [1] Neuroactive ligand-receptor interaction D03671 Deflazacort [2] 30, 113
24 NR3C1 [1] Neuroactive ligand-receptor interaction D05000 Methylprednisolone hemisuccinate [7] 13, 49, 50, 51, 53, 97, 211
25 NR3C1 [1] Neuroactive ligand-receptor interaction D07202 Halometasone [1] 162
26 NR3C1 [1] Neuroactive ligand-receptor interaction D07715 Clobetasol [4] 39, 46, 51, 162
27 NR3C1 [1] Neuroactive ligand-receptor interaction D07749 Cortisone [1] 81
28 NR3C1 [1] Neuroactive ligand-receptor interaction D07981 Fluticasone [3] 98, 228, 299
29 NR3C1 [1] Neuroactive ligand-receptor interaction D08227 Mometasone [2] 98, 162
30 NR3C1 [1] Neuroactive ligand-receptor interaction D08416 Prednisone acetate [6] 35, 41, 46, 49, 162, 224
31 NR3C1 [1] Neuroactive ligand-receptor interaction D11000 Vamorolone [2] 97, 113
32 NR3C1 [1] Neuroactive ligand-receptor interaction D11336 Relacorilant [1] 75
33 NPC1L1 [1] Fat digestion and absorption D01966 Ezetimibe [4] 49, 79, 93, 260
34 NR3C2 [1] Aldosterone-regulated sodium reabsorption D00443 Spironolactone [8] 46, 58, 67, 86, 113, 210, 218, 225
35 NR3C2 [1] Aldosterone-regulated sodium reabsorption D01115 Eplerenone [4] 75, 113, 210, 215
36 NR3C2 [1] Aldosterone-regulated sodium reabsorption D07967 Fludrocortisone [3] 6, 17, 81
37 NR3C2 [1] Aldosterone-regulated sodium reabsorption D10528 Aldosterone [1] 222
38 NFE2L2 [7] Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D10964 Omaveloxolone [1] 18
39 NFKB1 [76] Antifolate resistance, MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Cellular senescence, Osteoclast differentiation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Relaxin signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Pancreatic cancer, Prostate cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D01146 Iguratimod [5] 46, 51, 53, 271, 300
40 NGF [9] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels D09387 Tanezumab [2] 226, 298
41 NGFR [9] Virion - Lyssavirus, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin [2] 53, 90
42 NPR1 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion D04051 Erythrityl tetranitrate [1] 46
43 NPR1 [10] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion D05147 Nesiritide [2] 46, 58
44 NPR2 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway D04051 Erythrityl tetranitrate [1] 46
45 NPR2 [5] Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Oxytocin signaling pathway D11190 Vosoritide [1] 276
46 NR1H4 [1] Bile secretion D00163 Chenodeoxycholic acid [4] 20, 96, 234, 263
47 NR1H4 [1] Bile secretion D00734 Ursodeoxycholic acid [14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
48 NR1H4 [1] Bile secretion D09360 Obeticholic acid [3] 93, 265, 296
49 NR1H4 [1] Bile secretion D10699 Cholic Acid [4] 20, 234, 265, 310
50 NR1H4 [1] Bile secretion D11548 Tropifexor [1] 93