Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ITGA4	[14] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D06590	Firategrast	[1] 13
2	ITGA4	[14] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
3	ITGA4	[14] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D08083	Vedolizumab	[3] 94, 96, 97
4	ITGA4	[14] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D10540	Abrilumab	[2] 96, 97

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