Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
2	Adrenergic signaling in cardiomyocytes 💬	[5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
3	Alcoholism 💬	[1] DDC 💬	D00558 💬	Carbidopa	[7] 6 , 13, 17, 90, 140, 164, 201 💬
4	Alcoholism 💬	[2] DRD1, DRD2 💬	D00059 💬	Levodopa	[6] 6 , 17, 90, 140, 164, 201 💬
5	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
6	Aldosterone synthesis and secretion 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
7	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
8	Alzheimer disease 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
9	Amphetamine addiction 💬	[2] CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
10	Amphetamine addiction 💬	[6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬

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