Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
2 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
3 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
4 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
5 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
6 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A [1] SV2A 💬 |
D08879 D08879 💬 |
Brivaracetam | 149 [2] 149, 309 💬 |
7 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A [1] SV2A 💬 |
D00709 D00709 💬 |
Levetiracetam | 002 [5] 2 , 4 , 6 , 13, 307 💬 |
8 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A [3] SV2A, SV2B, SV2C 💬 |
D11842 D11842 💬 |
Padsevonil | 149 [1] 149 💬 |
9 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |
10 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
AXL [3] AXL, KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
11 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
12 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
13 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
BRAF [4] BRAF, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
14 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
15 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
16 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
17 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
18 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
19 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
20 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
EGFR [3] EGFR, ERBB2, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
21 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
22 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
FGFR2 [2] FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
23 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
FGFR2 [5] FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
24 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
25 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
26 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
27 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 [2] 46, 96 💬 |
28 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
29 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
30 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
31 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
32 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
33 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R [1] IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 |
34 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
35 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D11400 D11400 💬 |
Abrocitinib | 084 [1] 84 💬 |
36 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
37 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 |
38 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
39 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
40 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
41 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 |
42 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 [2] JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
43 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
KDR [1] KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
44 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
KDR [1] KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
45 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
KDR [3] KDR, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
46 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
47 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
48 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
49 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
50 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
51 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
52 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
53 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
54 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
55 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
56 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
57 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
58 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
59 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
60 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
61 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
62 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
63 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
64 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
65 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
66 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
67 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00297 D00297 💬 |
Digitoxin | 299 [1] 299 💬 |
68 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ATP1A1 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 |
D00298 D00298 💬 |
Digoxin | 008 [3] 8 , 46, 210 💬 |
69 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
70 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
71 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
72 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
73 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
74 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
75 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
76 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
77 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
78 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 |
79 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
80 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
81 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
82 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
83 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 |
84 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
85 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
PTH1R [1] PTH1R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 [4] 65, 70, 235, 326 💬 |
86 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
PTH1R [1] PTH1R 💬 |
D06078 D06078 💬 |
Teriparatide | 046 [7] 46, 65, 68, 70, 71, 235, 274 💬 |
87 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 [8] 41, 46, 49, 50, 96, 107, 235, 238 💬 |
88 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00122 D00122 💬 |
Calcifediol | 113 [2] 113, 299 💬 |
89 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D01125 D01125 💬 |
Calcipotriol | 036 [2] 36, 51 💬 |
90 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 018 [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬 |
91 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00188 D00188 💬 |
Cholecalciferol | 006 [24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 |
92 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00299 D00299 💬 |
Dihydrotachysterol | 006 [2] 6 , 85 💬 |
93 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D07578 D07578 💬 |
Eldecalcitol | 046 [1] 46 💬 |
94 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00187 D00187 💬 |
Ergocalciferol | 046 [6] 46, 49, 84, 96, 97, 299 💬 |
95 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR [1] VDR 💬 |
D00930 D00930 💬 |
Paricalcitol | 019 [5] 19, 66, 218, 238, 298 💬 |
96 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
97 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
98 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
99 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
CDK4 [1] CDK4 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
100 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
101 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
102 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
103 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
104 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
105 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
106 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
107 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
108 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
109 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 |
110 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
111 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
112 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
113 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
114 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
115 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
116 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
117 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
118 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
119 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
120 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
121 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 |
122 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
123 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
124 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
125 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
126 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
127 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
128 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
129 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
130 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
131 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
132 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
133 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
134 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
135 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
136 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
137 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
138 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
139 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
140 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
141 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
142 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
143 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
144 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
145 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 |
146 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
147 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
148 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
149 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
150 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
151 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
152 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
153 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
154 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
FGFR2 [2] FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
155 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
FGFR2 [3] FGFR2, FGFR3, PDGFRA 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
156 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
157 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
158 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
159 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
160 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
161 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
162 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
163 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
164 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
165 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
PML [1] PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
166 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
167 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
168 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
169 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
170 | Endocytosis 💬 Related to 15 target genes, 28 drugs (DrugBank) and 51 diseases in DDrare |
TFRC [1] TFRC 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 [1] 19 💬 |
171 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
172 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
173 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
174 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
175 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
176 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
177 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
178 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
179 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
180 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
181 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
182 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
183 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
184 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
185 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
186 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
187 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
188 | Endometrial cancer 💬 Related to 10 target genes, 18 drugs (DrugBank) and 20 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
189 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
ADAM17 [1] ADAM17 💬 |
D08859 D08859 💬 |
Apratastat | 046 [1] 46 💬 |
190 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
191 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
192 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
193 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
194 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
195 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
196 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
197 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
198 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
199 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
200 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
201 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
202 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
203 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
204 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
205 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
206 | Epithelial cell signaling in Helicobacter pylori infection 💬 Related to 12 target genes, 17 drugs (DrugBank) and 21 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
207 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
208 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 [2] 46, 61 💬 |
209 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 [3] 46, 49, 53 💬 |
210 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D12467 D12467 💬 |
Evobrutinib | 013 [3] 13, 46, 49 💬 |
211 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 [1] 13 💬 |
212 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 [3] 28, 60, 61 💬 |
213 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 [4] 13, 49, 61, 63 💬 |
214 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D12285 D12285 💬 |
Remibrutinib | 013 [2] 13, 53 💬 |
215 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
BTK [1] BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 013 [5] 13, 63, 222, 300, 331 💬 |
216 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
217 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD19 [1] CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 [4] 11, 13, 51, 300 💬 |
218 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD19 [1] CD19 💬 |
D11496 D11496 💬 |
Obexelimab | 300 [1] 300 💬 |
219 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 [1] 46 💬 |
220 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD3D [3] CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 [2] 96, 97 💬 |
221 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD3E [1] CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 [1] 49 💬 |
222 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
223 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
224 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
225 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CD58 [1] CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 [6] 37, 60, 65, 164, 284, 285 💬 |
226 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
227 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
HDAC1 [2] HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 075 [2] 75, 96 💬 |
228 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
229 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
230 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 [3] 46, 49, 53 💬 |
231 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 [6] 13, 25, 26, 28, 56, 96 💬 |
232 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 [1] 56 💬 |
233 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 [2] 25, 34 💬 |
234 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 [4] 13, 26, 96, 97 💬 |
235 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 [1] 13 💬 |
236 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IFNAR1 [2] IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 [1] 13 💬 |
237 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 [1] IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 [2] 46, 96 💬 |
238 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
239 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
240 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
241 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
242 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
243 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D11400 D11400 💬 |
Abrocitinib | 084 [1] 84 💬 |
244 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
245 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
246 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 |
247 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 |
248 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
249 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
250 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 [3] JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
251 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
252 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
253 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
254 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
255 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
256 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
257 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
258 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
259 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
260 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
261 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
262 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
263 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
264 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
265 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
266 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
267 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
268 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TYK2 [1] TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 049 [3] 49, 96, 97 💬 |
269 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
270 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
271 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
272 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
273 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
274 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
ABL1 [2] ABL1, SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
275 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
276 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
277 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
278 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
279 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
280 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
281 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
282 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
283 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
EGFR [3] EGFR, ERBB2, ERBB4 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
284 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
285 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
286 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
287 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
288 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
289 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR [1] MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
290 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR [1] MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 [40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
291 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR [1] MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 [1] 13 💬 |
292 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
293 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
294 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
295 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
296 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
297 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
298 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
299 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
300 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
301 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
302 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
303 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
304 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [1] ESR1 💬 |
D00554 D00554 💬 |
Ethinylestradiol | 013 [4] 13, 46, 49, 299 💬 |
305 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 [1] 74 💬 |
306 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 [1] 53 💬 |
307 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 [1] 53 💬 |
308 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 [7] 13, 46, 49, 65, 76, 226, 299 💬 |
309 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 [1] 65 💬 |
310 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 [2] 13, 227 💬 |
311 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 [2] 13, 227 💬 |
312 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 [2] 49, 86 💬 |
313 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 [2] 46, 49 💬 |
314 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 [6] 49, 53, 83, 86, 96, 113 💬 |
315 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 [1] 46 💬 |
316 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 [3] 2 , 113, 227 💬 |
317 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 [5] 60, 63, 64, 65, 285 💬 |
318 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
ESR1 [2] ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 [1] 230 💬 |
319 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 [2] 13, 206 💬 |
320 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 [1] 13 💬 |
321 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 |
322 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
GABBR1 [2] GABBR1, GABBR2 💬 |
D12240 D12240 💬 |
Valiloxybate | 006 [1] 6 💬 |
323 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
324 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
325 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
326 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
327 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
328 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
329 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D07132 D07132 💬 |
Buprenorphine | 046 [2] 46, 70 💬 |
330 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00838 D00838 💬 |
Dezocine | 046 [1] 46 💬 |
331 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D07831 D07831 💬 |
Dihydrocodeine | 310 [1] 310 💬 |
332 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D00320 D00320 💬 |
Fentanyl | 046 [3] 46, 70, 215 💬 |
333 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08047 D08047 💬 |
Hydromorphone | 070 [1] 70 💬 |
334 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08144 D08144 💬 |
Loperamide | 013 [2] 13, 97 💬 |
335 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08233 D08233 💬 |
Morphine | 036 [5] 36, 46, 70, 85, 86 💬 |
336 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08246 D08246 💬 |
Nalbuphine | 085 [1] 85 💬 |
337 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05111 D05111 💬 |
Nalmefene | 006 [1] 6 💬 |
338 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08249 D08249 💬 |
Naloxone | 006 [2] 6 , 226 💬 |
339 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
340 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05312 D05312 💬 |
Oxycodone | 006 [5] 6 , 13, 70, 226, 298 💬 |
341 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08323 D08323 💬 |
Oxymorphone | 070 [1] 70 💬 |
342 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08473 D08473 💬 |
Remifentanil | 006 [2] 6 , 70 💬 |
343 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D05938 D05938 💬 |
Sufentanil | 070 [2] 70, 280 💬 |
344 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08623 D08623 💬 |
Tramadol | 046 [5] 46, 70, 78, 226, 271 💬 |
345 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 [1] OPRM1 💬 |
D08639 D08639 💬 |
Trimebutine | 051 [1] 51 💬 |
346 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D01217 D01217 💬 |
Dydrogesterone | 013 [1] 13 💬 |
347 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00950 D00950 💬 |
Levonorgestrel | 013 [1] 13 💬 |
348 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00951 D00951 💬 |
Medroxyprogesterone acetate | 013 [8] 13, 35, 46, 49, 50, 51, 60, 107 💬 |
349 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00952 D00952 💬 |
Megestrol acetate | 076 [1] 76 💬 |
350 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00585 D00585 💬 |
Mifepristone | 075 [1] 75 💬 |
351 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D07222 D07222 💬 |
Nomegestrol | 013 [1] 13 💬 |
352 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D08281 D08281 💬 |
Nomegestrol acetate | 013 [1] 13 💬 |
353 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00182 D00182 💬 |
Norethisterone | 013 [4] 13, 46, 49, 299 💬 |
354 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D05209 D05209 💬 |
Norgestimate | 299 [1] 299 💬 |
355 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D00066 D00066 💬 |
Progesterone | 076 [2] 76, 299 💬 |
356 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PGR [1] PGR 💬 |
D09567 D09567 💬 |
Ulipristal | 010 [1] 10 💬 |
357 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
358 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
359 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
360 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
PRKCD [1] PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
361 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
362 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
363 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
364 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D04162 D04162 💬 |
Fenretinide | 299 [1] 299 💬 |
365 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 [4] 36, 39, 159, 160 💬 |
366 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D01418 D01418 💬 |
Tamibarotene | 026 [2] 26, 96 💬 |
367 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 [6] 2 , 62, 63, 75, 94, 231 💬 |
368 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
RARA [1] RARA 💬 |
D06543 D06543 💬 |
Vitamin A | 013 [3] 13, 53, 90 💬 |
369 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
370 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
371 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
372 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
373 | Ether lipid metabolism 💬 Related to 1 target gene, 1 drug (DrugBank) and 2 diseases in DDrare |
ENPP2 [1] ENPP2 💬 |
D11844 D11844 💬 |
Ziritaxestat | 051 [2] 51, 85 💬 |