Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Yersinia infection 💬
 [5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 Yersinia infection 💬
 [1] CD4 💬 D06356 💬 Zanolimumab [1] 46 💬
3 Yersinia infection 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
4 Yersinia infection 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
5 Yersinia infection 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
6 Yersinia infection 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
7 Yersinia infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
8 Yersinia infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
9 Yersinia infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
10 Yersinia infection 💬
 [1] ITGA4 💬 D10540 💬 Abrilumab [2] 96, 97 💬
11 Yersinia infection 💬
 [1] ITGA4 💬 D06590 💬 Firategrast [1] 13 💬
12 Yersinia infection 💬
 [1] ITGA4 💬 D06886 💬 Natalizumab [6] 13, 15, 25, 46, 63, 96 💬
13 Yersinia infection 💬
 [1] ITGA4 💬 D08083 💬 Vedolizumab [3] 94, 96, 97 💬
14 Yersinia infection 💬
 [2] LCK, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
15 Yersinia infection 💬
 [2] LCK, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
16 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
17 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
18 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
19 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
20 Yersinia infection 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
21 Yersinia infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
22 Yersinia infection 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
23 Yersinia infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
24 Yersinia infection 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
25 Yersinia infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
26 Yersinia infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
27 Yersinia infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
28 Yersinia infection 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
29 Yersinia infection 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [2] 51, 85 💬
30 Yersinia infection 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
31 Yersinia infection 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
32 Yersinia infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
33 Yersinia infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
34 Yersinia infection 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
35 Yersinia infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
36 Yersinia infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
37 Yersinia infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
38 Yersinia infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
39 Yersinia infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
40 Yersinia infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬