Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Valine, leucine and isoleucine degradation 💬 Related to 1 target gene, 2 drugs (DrugBank) and 16 diseases in DDrare |
ABAT [1] ABAT 💬 |
D00399 D00399 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
2 | Valine, leucine and isoleucine degradation 💬 Related to 1 target gene, 2 drugs (DrugBank) and 16 diseases in DDrare |
ABAT [1] ABAT 💬 |
D00535 D00535 💬 |
Vigabatrin | 145 [2] 145, 158 💬 |
3 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
4 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
5 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 [1] 6 💬 |
6 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 [1] 6 💬 |
7 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
8 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D12568 D12568 💬 |
Regadenoson | 058 [1] 58 💬 |
9 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 [1] 6 💬 |
10 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
11 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
12 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
13 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
14 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
15 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 [1] 13 💬 |
16 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [1] ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 [2] 6 , 13 💬 |
17 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
18 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00255 D00255 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 |
19 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
20 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 [2] 57, 67 💬 |
21 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
22 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
23 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
24 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 280 [1] 280 💬 |
25 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 [3] 6 , 17, 58 💬 |
26 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [2] 22, 296 💬 |
27 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
28 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 [1] 22 💬 |
29 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
30 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08560 D08560 💬 |
Tamsulosin | 013 [1] 13 💬 |
31 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 [1] 6 💬 |
32 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
33 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
34 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
35 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
36 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
37 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
38 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
39 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
40 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 [2] AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
41 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AVPR1A [1] AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
42 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
D06672 D06672 💬 |
Terlipressin | 299 [1] 299 💬 |
43 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AVPR1A [2] AVPR1A, AVPR1B 💬 |
D00101 D00101 💬 |
Vasopressin | 210 [1] 210 💬 |
44 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
45 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
46 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
47 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
48 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
49 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
50 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
51 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
52 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
53 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
54 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
55 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
56 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
57 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
CALCA [1] CALCA 💬 |
D11055 D11055 💬 |
Fremanezumab | 124 [2] 124, 226 💬 |
58 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
59 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
60 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
61 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
62 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
63 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
64 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
65 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
66 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
67 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
68 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
69 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
70 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
71 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
72 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
NPR1 [2] NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
73 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
NPR2 [1] NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 [1] 276 💬 |
74 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
75 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PRKCD [4] PRKCD, PRKCE, PRKCH, PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 [1] 97 💬 |
76 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D02720 D02720 💬 |
Beraprost | 086 [1] 86 💬 |
77 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D00106 D00106 💬 |
Epoprostenol | 086 [1] 86 💬 |
78 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
79 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D02721 D02721 💬 |
Iloprost | 051 [4] 51, 84, 85, 86 💬 |
80 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D10725 D10725 💬 |
Ralinepag | 086 [1] 86 💬 |
81 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 [5] 51, 70, 84, 86, 88 💬 |
82 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
PTGIR [1] PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 [6] 51, 84, 85, 86, 88, 210 💬 |
83 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
84 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [2] 51, 85 💬 |
85 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D07748 D07748 💬 |
Conivaptan | 086 [1] 86 💬 |
86 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
87 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D04752 D04752 💬 |
Lixivaptan | 067 [1] 67 💬 |
88 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D06672 D06672 💬 |
Terlipressin | 299 [1] 299 💬 |
89 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D01213 D01213 💬 |
Tolvaptan | 067 [4] 67, 72, 86, 225 💬 |
90 | Vasopressin-regulated water reabsorption 💬 Related to 1 target gene, 6 drugs (DrugBank) and 10 diseases in DDrare |
AVPR2 [1] AVPR2 💬 |
D00101 D00101 💬 |
Vasopressin | 210 [1] 210 💬 |
91 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
92 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
93 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
94 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
95 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
96 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
97 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [1] KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
98 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
KDR [2] KDR, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
99 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
100 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
101 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
102 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
103 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
104 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
105 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
106 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
107 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
108 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
109 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
110 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
111 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
112 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
113 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 049 [2] 49, 222 💬 |
114 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
115 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
116 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
117 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
118 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
119 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
120 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
121 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
122 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
123 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
124 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
125 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
126 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
127 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
128 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
129 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
130 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
131 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
132 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
133 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
134 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
135 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
136 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
137 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
138 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
139 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
140 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
141 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
142 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
143 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
144 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
145 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
146 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11423 D11423 💬 |
Deutivacaftor | 299 [1] 299 💬 |
147 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11507 D11507 💬 |
Elexacaftor | 299 [1] 299 💬 |
148 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11724 D11724 💬 |
Galicaftor | 299 [1] 299 💬 |
149 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D09916 D09916 💬 |
Ivacaftor | 299 [1] 299 💬 |
150 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D10134 D10134 💬 |
Lumacaftor | 299 [1] 299 💬 |
151 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
CFTR [1] CFTR 💬 |
D11041 D11041 💬 |
Tezacaftor | 299 [1] 299 💬 |
152 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
KCNQ1 [1] KCNQ1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
153 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
KCNQ1 [1] KCNQ1 💬 |
D09569 D09569 💬 |
Ezogabine | 002 [2] 2 , 144 💬 |
154 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
SLC12A2 [1] SLC12A2 💬 |
D00247 D00247 💬 |
Bumetanide | 006 [2] 6 , 158 💬 |
155 | Vibrio cholerae infection 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
SLC12A2 [1] SLC12A2 💬 |
D00331 D00331 💬 |
Furosemide | 006 [2] 6 , 86 💬 |
156 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 |
157 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
CCR4 [1] CCR4 💬 |
D09761 D09761 💬 |
Mogamulizumab | 026 [1] 26 💬 |
158 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
159 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
160 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
CDK4 [2] CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 [1] 34 💬 |
161 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
HDAC1 [11] HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 💬 |
D06320 D06320 💬 |
Vorinostat | 075 [2] 75, 96 💬 |
162 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D11400 D11400 💬 |
Abrocitinib | 084 [1] 84 💬 |
163 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 [13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
164 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 [6] 46, 53, 96, 97, 222, 271 💬 |
165 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 [4] 46, 51, 97, 228 💬 |
166 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 060 [3] 60, 65, 228 💬 |
167 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [1] JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 [8] 40, 41, 46, 49, 96, 97, 107, 271 💬 |
168 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 [1] 46 💬 |
169 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 [2] JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 |
170 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
171 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
172 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
173 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
174 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
175 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
176 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
177 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
178 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
179 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
SYK [1] SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 [4] 46, 49, 61, 66 💬 |
180 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
181 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
182 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CD4 [1] CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 [1] 46 💬 |
183 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 |
184 | Viral life cycle - HIV-1 💬 Related to 4 target genes, 5 drugs (DrugBank) and 9 diseases in DDrare |
XPO1 [1] XPO1 💬 |
D11222 D11222 💬 |
Selinexor | 028 [1] 28 💬 |
185 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
186 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
187 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
188 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
189 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [2] ABL1, FYN 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
190 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ABL1 [2] ABL1, FYN 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
191 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CASP9 [1] CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 [6] 19, 60, 65, 284, 285, 326 💬 |
192 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD40 [1] CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 [1] 222 💬 |
193 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD40 [1] CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 [2] 49, 53 💬 |
194 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD40 [1] CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 [2] 53, 97 💬 |
195 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD40LG [1] CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 [1] 63 💬 |
196 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
197 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
198 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
DMD [1] DMD 💬 |
D11988 D11988 💬 |
Casimersen | 113 [1] 113 💬 |
199 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
DMD [1] DMD 💬 |
D10114 D10114 💬 |
Drisapersen | 113 [1] 113 💬 |
200 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
DMD [1] DMD 💬 |
D09900 D09900 💬 |
Eteplirsen | 113 [1] 113 💬 |
201 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
DMD [1] DMD 💬 |
D11707 D11707 💬 |
Golodirsen | 113 [1] 113 💬 |
202 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
DMD [1] DMD 💬 |
D11528 D11528 💬 |
Viltolarsen | 113 [1] 113 💬 |
203 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
204 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
MYH7 [1] MYH7 💬 |
D12265 D12265 💬 |
Mavacamten | 058 [1] 58 💬 |
205 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CCL2 [4] CCL2, IL10, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
206 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CCR2 [2] CCR2, CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
207 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CCR4 [1] CCR4 💬 |
D09761 D09761 💬 |
Mogamulizumab | 026 [1] 26 💬 |
208 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
209 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CSF1R [1] CSF1R 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
210 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CSF1R [1] CSF1R 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
211 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR1 [2] CXCR1, CXCR2 💬 |
D08984 D08984 💬 |
Reparixin | 298 [2] 298, 299 💬 |
212 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 |
213 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL20 [1] IL20 💬 |
D11756 D11756 💬 |
Fletikumab | 046 [1] 46 💬 |
214 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 [6] 2 , 50, 66, 97, 222, 228 💬 |
215 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL2RA [1] IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 [8] 13, 56, 60, 65, 97, 107, 283, 284 💬 |
216 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL2RA [3] IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 [6] 2 , 35, 49, 65, 96, 97 💬 |
217 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 [2] 46, 96 💬 |
218 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
219 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
220 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
221 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6R [1] IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 [5] 41, 46, 84, 107, 271 💬 |
222 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6R [1] IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 [3] 11, 13, 86 💬 |
223 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6R [1] IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 [21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
224 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
LTA [1] LTA 💬 |
D10187 D10187 💬 |
Pateclizumab | 046 [1] 46 💬 |
225 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
LTA [2] LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
226 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
227 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
228 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
229 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
230 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
231 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
232 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
233 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
234 | Virion - Adenovirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 26 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
235 | Virion - Adenovirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 26 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
236 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D09878 D09878 💬 |
Cenicriviroc | 094 [1] 94 💬 |
237 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CCR5 [1] CCR5 💬 |
D06670 D06670 💬 |
Maraviroc | 046 [2] 46, 84 💬 |
238 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CD4 [1] CD4 💬 |
D06356 D06356 💬 |
Zanolimumab | 046 [1] 46 💬 |
239 | Virion - Human immunodeficiency virus 💬 Related to 3 target genes, 4 drugs (DrugBank) and 8 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 |
240 | Virion - Lyssavirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 5 diseases in DDrare |
CHRNA1 [1] CHRNA1 💬 |
D03365 D03365 💬 |
Nicotine | 006 [3] 6 , 13, 84 💬 |
241 | Virion - Lyssavirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 5 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |