Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Malaria 💬
 [5] CCL2, IL10, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 Malaria 💬
 [1] CD40 💬 D11357 💬 Bleselumab [1] 222 💬
3 Malaria 💬
 [1] CD40 💬 D11610 💬 Iscalimab [2] 49, 53 💬
4 Malaria 💬
 [1] CD40 💬 D11597 💬 Ravagalimab [2] 53, 97 💬
5 Malaria 💬
 [1] CD40LG 💬 D06193 💬 Toralizumab [1] 63 💬
6 Malaria 💬
 [1] IFNG 💬 D11120 💬 Emapalumab [3] 49, 65, 107 💬
7 Malaria 💬
 [1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
8 Malaria 💬
 [1] IL12A 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
9 Malaria 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
10 Malaria 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
11 Malaria 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
12 Malaria 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
13 Malaria 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
14 Malaria 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
15 Malaria 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
16 Malaria 💬
 [1] ITGAL 💬 D03959 💬 Efalizumab [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
17 Malaria 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
18 Malaria 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
19 Malaria 💬
 [1] TLR9 💬 D12275 💬 Cobitolimod [1] 97 💬
20 Malaria 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
21 Malaria 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
22 Malaria 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
23 Malaria 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
24 Malaria 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
25 Malaria 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
26 Malaria 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
27 Malaria 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
28 Malaria 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
29 MAPK signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
30 MAPK signaling pathway 💬
 [7] BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
31 MAPK signaling pathway 💬
 [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
32 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
33 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
34 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
35 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
36 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
37 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
38 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
39 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
40 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
41 MAPK signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [4] 58, 96, 140, 167 💬
42 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine [1] 149 💬
43 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
44 MAPK signaling pathway 💬
 [3] CACNA1G, CACNA1H, CACNA1I 💬 D00538 💬 Zonisamide [1]  6  💬
45 MAPK signaling pathway 💬
 [2] CACNA2D1, CACNA2D2 💬 D11203 💬 Mirogabalin [1] 70 💬
46 MAPK signaling pathway 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
47 MAPK signaling pathway 💬
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D02716 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
48 MAPK signaling pathway 💬
 [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
49 MAPK signaling pathway 💬
 [3] CSF1R, FLT3, KIT 💬 D11270 💬 Pexidartinib [1] 34 💬
50 MAPK signaling pathway 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
51 MAPK signaling pathway 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
52 MAPK signaling pathway 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
53 MAPK signaling pathway 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
54 MAPK signaling pathway 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
55 MAPK signaling pathway 💬
 [3] EGFR, ERBB2, ERBB4 💬 D08950 💬 Neratinib [1] 34 💬
56 MAPK signaling pathway 💬
 [4] EGFR, ERBB2, FLT4, KDR 💬 D11772 💬 Tesevatinib [1] 67 💬
57 MAPK signaling pathway 💬
 [3] EPHA2, KIT, PDGFRB 💬 D03658 💬 Dasatinib [2] 51, 85 💬
58 MAPK signaling pathway 💬
 [3] EPHA2, KIT, PDGFRB 💬 D06414 💬 Dasatinib [2] 51, 85 💬
59 MAPK signaling pathway 💬
 [1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
60 MAPK signaling pathway 💬
 [3] FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
61 MAPK signaling pathway 💬
 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
62 MAPK signaling pathway 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
63 MAPK signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 D03218 💬 Axitinib [1] 34 💬
64 MAPK signaling pathway 💬
 [3] FLT1, FLT4, KDR 💬 D08881 💬 Cediranib [1] 34 💬
65 MAPK signaling pathway 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
66 MAPK signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
67 MAPK signaling pathway 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
68 MAPK signaling pathway 💬
 [1] IL1A 💬 D11253 💬 Bermekimab [1] 51 💬
69 MAPK signaling pathway 💬
 [2] IL1A, IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
70 MAPK signaling pathway 💬
 [3] IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
71 MAPK signaling pathway 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
72 MAPK signaling pathway 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
73 MAPK signaling pathway 💬
 [1] IL1R1 💬 D02934 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
74 MAPK signaling pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
75 MAPK signaling pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
76 MAPK signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
77 MAPK signaling pathway 💬
 [2] KDR, MET 💬 D10062 💬 Cabozantinib [1] 34 💬
78 MAPK signaling pathway 💬
 [1] KIT 💬 D10229 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
79 MAPK signaling pathway 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
80 MAPK signaling pathway 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
81 MAPK signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
82 MAPK signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
83 MAPK signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
84 MAPK signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
85 MAPK signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
86 MAPK signaling pathway 💬
 [1] MAP3K5 💬 D10988 💬 Selonsertib [1] 86 💬
87 MAPK signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
88 MAPK signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
89 MAPK signaling pathway 💬
 [1] MAPT 💬 D11210 💬 Flortaucipir [3]  5 ,  7 , 127 💬
90 MAPK signaling pathway 💬
 [1] MAPT 💬 D11293 💬 Gosuranemab [1]  5  💬
91 MAPK signaling pathway 💬
 [1] MAPT 💬 D11384 💬 Hydromethylthionine mesylate [1] 127 💬
92 MAPK signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
93 MAPK signaling pathway 💬
 [1] NGF 💬 D09387 💬 Tanezumab [2] 226, 298 💬
94 MAPK signaling pathway 💬
 [1] NGFR 💬 D11028 💬 Cenegermin [2] 53, 90 💬
95 MAPK signaling pathway 💬
 [3] PGF, VEGFA, VEGFB 💬 D09574 💬 Aflibercept [2] 90, 166 💬
96 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
97 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
98 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
99 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
100 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
101 MAPK signaling pathway 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
102 MAPK signaling pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
103 MAPK signaling pathway 💬
 [3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
104 MAPK signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
105 MAPK signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
106 MAPK signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
107 MAPK signaling pathway 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
108 MAPK signaling pathway 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
109 MAPK signaling pathway 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
110 MAPK signaling pathway 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
111 MAPK signaling pathway 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
112 MAPK signaling pathway 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
113 MAPK signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
114 MAPK signaling pathway 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
115 MAPK signaling pathway 💬
 [1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬
116 Measles 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
117 Measles 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
118 Measles 💬
 [3] CD3D, CD3E, CD3G 💬 D08959 💬 Otelixizumab [1] 46 💬
119 Measles 💬
 [3] CD3D, CD3E, CD3G 💬 D06314 💬 Visilizumab [2] 96, 97 💬
120 Measles 💬
 [1] CD3E 💬 D11463 💬 Mosunetuzumab [1] 49 💬
121 Measles 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
122 Measles 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
123 Measles 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
124 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [3] 46, 49, 53 💬
125 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
126 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
127 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
128 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
129 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
130 Measles 💬
 [2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
131 Measles 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
132 Measles 💬
 [1] IL1A 💬 D11253 💬 Bermekimab [1] 51 💬
133 Measles 💬
 [2] IL1A, IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
134 Measles 💬
 [3] IL1A, IL1B, IL6 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
135 Measles 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
136 Measles 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
137 Measles 💬
 [1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
138 Measles 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
139 Measles 💬
 [3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
140 Measles 💬
 [1] IL6 💬 D12487 💬 Olokizumab [2] 46, 96 💬
141 Measles 💬
 [1] IL6 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
142 Measles 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
143 Measles 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
144 Measles 💬
 [1] JAK1 💬 D11400 💬 Abrocitinib [1] 84 💬
145 Measles 💬
 [1] JAK1 💬 D10308 💬 Baricitinib [13]  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
146 Measles 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
147 Measles 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [4] 46, 51, 97, 228 💬
148 Measles 💬
 [1] JAK1 💬 D09959 💬 Ruxolitinib [3] 60, 65, 228 💬
149 Measles 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
150 Measles 💬
 [2] JAK1, JAK3 💬 D10653 💬 Peficitinib [1] 46 💬
151 Measles 💬
 [3] JAK1, JAK3, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
152 Measles 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
153 Measles 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
154 Measles 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
155 Measles 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
156 Measles 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
157 Measles 💬
 [1] TLR7 💬 D02500 💬 Imiquimod [2] 34, 51 💬
158 Measles 💬
 [1] TLR9 💬 D12275 💬 Cobitolimod [1] 97 💬
159 Measles 💬
 [1] TYK2 💬 D11817 💬 Deucravacitinib [3] 49, 96, 97 💬
160 Melanogenesis 💬
 [1] EDNRB 💬 D01227 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
161 Melanogenesis 💬
 [1] EDNRB 💬 D07538 💬 Bosentan [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
162 Melanogenesis 💬
 [1] EDNRB 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
163 Melanogenesis 💬
 [1] KIT 💬 D03658 💬 Dasatinib [2] 51, 85 💬
164 Melanogenesis 💬
 [1] KIT 💬 D06414 💬 Dasatinib [2] 51, 85 💬
165 Melanogenesis 💬
 [1] KIT 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
166 Melanogenesis 💬
 [1] KIT 💬 D10229 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
167 Melanogenesis 💬
 [1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
168 Melanogenesis 💬
 [1] KIT 💬 D11270 💬 Pexidartinib [1] 34 💬
169 Melanogenesis 💬
 [1] KIT 💬 D08552 💬 Sunitinib [2] 28, 34 💬
170 Melanogenesis 💬
 [2] KIT, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
171 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
172 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
173 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
174 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
175 Melanogenesis 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
176 Melanogenesis 💬
 [1] MC1R 💬 D10511 💬 Afamelanotide [3] 159, 161, 254 💬
177 Melanogenesis 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
178 Melanoma 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
179 Melanoma 💬
 [3] BRAF, PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
180 Melanoma 💬
 [2] CDK4, CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
181 Melanoma 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
182 Melanoma 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
183 Melanoma 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
184 Melanoma 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
185 Melanoma 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
186 Melanoma 💬
 [1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
187 Melanoma 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
188 Melanoma 💬
 [1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
189 Melanoma 💬
 [1] FGFR1 💬 D11589 💬 Infigratinib [1] 276 💬
190 Melanoma 💬
 [3] FGFR1, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
191 Melanoma 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
192 Melanoma 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
193 Melanoma 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
194 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
195 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
196 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
197 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
198 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
199 Melanoma 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
200 Melanoma 💬
 [1] PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
201 Melanoma 💬
 [2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
202 Melanoma 💬
 [2] PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
203 Melanoma 💬
 [1] PDGFRB 💬 D03658 💬 Dasatinib [2] 51, 85 💬
204 Melanoma 💬
 [1] PDGFRB 💬 D06414 💬 Dasatinib [2] 51, 85 💬
205 Melanoma 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
206 Melanoma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
207 Melanoma 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
208 Metabolic pathways 💬
 [1] ABAT 💬 D00535 💬 Vigabatrin [2] 145, 158 💬
209 Metabolic pathways 💬
 [4] ABAT, ALDH5A1, GAD1, GAD2 💬 D00399 💬 Valproic acid [14]  2 ,  3 ,  5 ,  6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
210 Metabolic pathways 💬
 [3] ADH1A, ADH1B, ADH1C 💬 D00707 💬 Fomepizole [1] 301 💬
211 Metabolic pathways 💬
 [1] ALAS1 💬 D11702 💬 Givosiran [1] 254 💬
212 Metabolic pathways 💬
 [2] ALAS1, ALAS2 💬 D10003 💬 Hemin [1] 254 💬
213 Metabolic pathways 💬
 [1] ALOX5 💬 D01773 💬 Oxatomide [1] 113 💬
214 Metabolic pathways 💬
 [1] ALOX5 💬 D00414 💬 Zileuton [3] 85, 160, 164 💬
215 Metabolic pathways 💬
 [1] ALPL 💬 D10595 💬 Asfotase alfa [1] 172 💬
216 Metabolic pathways 💬
 [5] AMY2A, AMY2B, GAA, GANC, MGAM 💬 D00216 💬 Acarbose [1] 298 💬
217 Metabolic pathways 💬
 [1] ANPEP 💬 D00087 💬 Ubenimex [1] 86 💬
218 Metabolic pathways 💬
 [1] AOC3 💬 D08044 💬 Hydralazine [1] 67 💬
219 Metabolic pathways 💬
 [1] ARSB 💬 D06565 💬 Galsulfase [1] 19 💬
220 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D08903 💬 Dexlansoprazole [1] 98 💬
221 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D07917 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
222 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00355 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
223 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
224 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D05353 💬 Pantoprazole [2] 13, 65 💬
225 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D08463 💬 Rabeprazole [2]  2 , 51 💬
226 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 D11784 💬 Vonoprazan [2] 63, 98 💬
227 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
228 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00518 💬 Diclofenamide [1] 114 💬
229 Metabolic pathways 💬
 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D07871 💬 Dorzolamide [1] 90 💬
230 Metabolic pathways 💬
 [2] CA2, CA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
231 Metabolic pathways 💬
 [1] CD38 💬 D10777 💬 Daratumumab [5] 13, 28, 48, 49, 63 💬
232 Metabolic pathways 💬
 [1] CD38 💬 D11050 💬 Isatuximab [3] 28, 61, 283 💬
233 Metabolic pathways 💬
 [1] CD38 💬 D11945 💬 Mezagitamab [2] 63, 66 💬
234 Metabolic pathways 💬
 [1] COMT 💬 D00781 💬 Entacapone [2]  6 , 17 💬
235 Metabolic pathways 💬
 [1] COMT 💬 D10825 💬 Opicapone [1]  6  💬
236 Metabolic pathways 💬
 [1] COMT 💬 D00786 💬 Tolcapone [3]  6 , 28, 127 💬
237 Metabolic pathways 💬
 [1] CPS1 💬 D07130 💬 Carglumic acid [3] 245, 246, 251 💬
238 Metabolic pathways 💬
 [3] CYP11A1, CYP11B1, CYP17A1 💬 D10950 💬 Levoketoconazole [1] 75 💬
239 Metabolic pathways 💬
 [1] CYP11B1 💬 D00410 💬 Metyrapone [1] 75 💬
240 Metabolic pathways 💬
 [1] CYP11B2 💬 D11061 💬 Osilodrostat [1] 75 💬
241 Metabolic pathways 💬
 [1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
242 Metabolic pathways 💬
 [1] CYP19A1 💬 D00960 💬 Anastrozole [3] 78, 86, 193 💬
243 Metabolic pathways 💬
 [1] CYP19A1 💬 D00964 💬 Letrozole [2] 81, 89 💬
244 Metabolic pathways 💬
 [1] DDC 💬 D03082 💬 Benserazide [1]  6  💬
245 Metabolic pathways 💬
 [1] DDC 💬 D00558 💬 Carbidopa [7]  6 , 13, 17, 90, 140, 164, 201 💬
246 Metabolic pathways 💬
 [2] DHFR, DHFR2 💬 D00142 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
247 Metabolic pathways 💬
 [1] DHODH 💬 D00749 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
248 Metabolic pathways 💬
 [1] DHODH 💬 D10172 💬 Teriflunomide [3] 13, 25, 26 💬
249 Metabolic pathways 💬
 [3] DNMT1, DNMT3A, DNMT3B 💬 D03665 💬 Decitabine [3] 13, 60, 63 💬
250 Metabolic pathways 💬
 [1] ENPP2 💬 D11844 💬 Ziritaxestat [2] 51, 85 💬
251 Metabolic pathways 💬
 [1] FDPS 💬 D07119 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
252 Metabolic pathways 💬
 [1] FDPS 💬 D07281 💬 Pamidronic acid [3] 270, 271, 274 💬
253 Metabolic pathways 💬
 [1] FDPS 💬 D08484 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
254 Metabolic pathways 💬
 [1] FDPS 💬 D01968 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
255 Metabolic pathways 💬
 [1] FDPS 💬 D08689 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
256 Metabolic pathways 💬
 [1] GAA 💬 D03207 💬 Alglucosidase alfa [1] 256 💬
257 Metabolic pathways 💬
 [1] GAA 💬 D11744 💬 Avalglucosidase alfa [1] 256 💬
258 Metabolic pathways 💬
 [1] GAA 💬 D11798 💬 Cipaglucosidase alfa [1] 256 💬
259 Metabolic pathways 💬
 [1] GAA 💬 D09605 💬 Duvoglustat [1] 256 💬
260 Metabolic pathways 💬
 [1] GALNS 💬 D10333 💬 Elosulfase alfa [1] 19 💬
261 Metabolic pathways 💬
 [1] GBA1 💬 D02810 💬 Alglucerase [1] 19 💬
262 Metabolic pathways 💬
 [1] GBA1 💬 D03020 💬 Imiglucerase [1] 19 💬
263 Metabolic pathways 💬
 [1] GBA1 💬 D09675 💬 Taliglucerase alfa [1] 19 💬
264 Metabolic pathways 💬
 [1] GBA1 💬 D09029 💬 Velaglucerase alfa [1] 19 💬
265 Metabolic pathways 💬
 [1] GLA 💬 D02784 💬 Agalsidase alfa [1] 19 💬
266 Metabolic pathways 💬
 [1] GLA 💬 D03228 💬 Agalsidase beta [1] 19 💬
267 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
268 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
269 Metabolic pathways 💬
 [1] GUCY2C 💬 D09355 💬 Linaclotide [2]  6 , 97 💬
270 Metabolic pathways 💬
 [1] GUSB 💬 D11004 💬 Vestronidase alfa [1] 19 💬
271 Metabolic pathways 💬
 [1] HAO1 💬 D11925 💬 Lumasiran [1] 234 💬
272 Metabolic pathways 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
273 Metabolic pathways 💬
 [1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
274 Metabolic pathways 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
275 Metabolic pathways 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
276 Metabolic pathways 💬
 [1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
277 Metabolic pathways 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
278 Metabolic pathways 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
279 Metabolic pathways 💬
 [1] HPD 💬 D05177 💬 Nitisinone [3]  6 , 164, 241 💬
280 Metabolic pathways 💬
 [1] HPRT1 💬 D00161 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
281 Metabolic pathways 💬
 [1] HPRT1 💬 D04931 💬 Mercaptopurine [4] 65, 96, 97, 164 💬
282 Metabolic pathways 💬
 [1] HPRT1 💬 D08603 💬 Tioguanine [2] 13, 37 💬
283 Metabolic pathways 💬
 [1] IDS 💬 D04499 💬 Idursulfase [1] 19 💬
284 Metabolic pathways 💬
 [1] IDS 💬 D11025 💬 Idursulfase beta [1] 19 💬
285 Metabolic pathways 💬
 [1] IDS 💬 D11812 💬 Pabinafusp alfa [1] 19 💬
286 Metabolic pathways 💬
 [1] IDUA 💬 D04670 💬 Laronidase [2] 19, 256 💬
287 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D01392 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
288 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D00752 💬 Mycophenolate mofetil [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
289 Metabolic pathways 💬
 [2] IMPDH1, IMPDH2 💬 D05096 💬 Mycophenolic acid [36]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
290 Metabolic pathways 💬
 [1] MAOA 💬 D02561 💬 Moclobemide [1]  6  💬
291 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D02579 💬 Iproniazid [1]  6  💬
292 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D08349 💬 Phenelzine [1]  6  💬
293 Metabolic pathways 💬
 [2] MAOA, MAOB 💬 D05458 💬 Phentermine [1] 97 💬
294 Metabolic pathways 💬
 [1] MAOB 💬 D08469 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
295 Metabolic pathways 💬
 [1] MAOB 💬 D10829 💬 Rasagiline [6]  2 ,  5 ,  6 , 17, 58, 66 💬
296 Metabolic pathways 💬
 [1] MAOB 💬 D10158 💬 Safinamide [2]  6 , 17 💬
297 Metabolic pathways 💬
 [1] MAOB 💬 D03731 💬 Selegiline [1]  6  💬
298 Metabolic pathways 💬
 [1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
299 Metabolic pathways 💬
 [2] NPR1, NPR2 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
300 Metabolic pathways 💬
 [1] NPR2 💬 D11190 💬 Vosoritide [1] 276 💬
301 Metabolic pathways 💬
 [2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
302 Metabolic pathways 💬
 [1] ODC1 💬 D07883 💬 Eflornithine [1] 65 💬
303 Metabolic pathways 💬
 [1] PAH 💬 D11077 💬 Pegvaliase [1] 240 💬
304 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00227 💬 Aminophylline [1] 63 💬
305 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07546 💬 Bucladesine [1] 246 💬
306 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
307 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00371 💬 Theophylline [2] 236, 299 💬
308 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D06103 💬 Theophylline [2] 236, 299 💬
309 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D00528 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
310 Metabolic pathways 💬
 [9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 D01453 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
311 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 46, 51, 70 💬
312 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
313 Metabolic pathways 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
314 Metabolic pathways 💬
 [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
315 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬
316 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [4] 84, 97, 206, 299 💬
317 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
318 Metabolic pathways 💬
 [2] PDE4A, PDE5A 💬 D00302 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬
319 Metabolic pathways 💬
 [1] PDE4D 💬 D12173 💬 Zatolmilast [1] 206 💬
320 Metabolic pathways 💬
 [1] PDE5A 💬 D08514 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
321 Metabolic pathways 💬
 [1] PDE5A 💬 D02008 💬 Tadalafil [7]  6 , 51, 75, 84, 86, 113, 210 💬
322 Metabolic pathways 💬
 [1] PDE5A 💬 D10027 💬 Udenafil [2] 86, 210 💬
323 Metabolic pathways 💬
 [1] PDE5A 💬 D08668 💬 Vardenafil [3] 13, 86, 299 💬
324 Metabolic pathways 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
325 Metabolic pathways 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
326 Metabolic pathways 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
327 Metabolic pathways 💬
 [3] PTGES, PTGS1, PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
328 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
329 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
330 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
331 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
332 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
333 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
334 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
335 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
336 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
337 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
338 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
339 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
340 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
341 Metabolic pathways 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
342 Metabolic pathways 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
343 Metabolic pathways 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
344 Metabolic pathways 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
345 Metabolic pathways 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
346 Metabolic pathways 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
347 Metabolic pathways 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
348 Metabolic pathways 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
349 Metabolic pathways 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
350 Metabolic pathways 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
351 Metabolic pathways 💬
 [1] RRM1 💬 D01370 💬 Cladribine [3] 11, 13, 94 💬
352 Metabolic pathways 💬
 [1] RRM1 💬 D03546 💬 Clofarabine [5] 19, 20, 60, 234, 326 💬
353 Metabolic pathways 💬
 [1] RRM1 💬 D07966 💬 Fludarabine [20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
354 Metabolic pathways 💬
 [1] RRM2 💬 D00341 💬 Hydroxyurea [8]  3 , 13, 19, 20, 65, 85, 86, 284 💬
355 Metabolic pathways 💬
 [1] SMPD1 💬 D10820 💬 Olipudase alfa [1] 19 💬
356 Metabolic pathways 💬
 [2] SRD5A1, SRD5A2 💬 D03820 💬 Dutasteride [2]  1 ,  2  💬
357 Metabolic pathways 💬
 [1] SRD5A2 💬 D00321 💬 Finasteride [1]  6  💬
358 Metabolic pathways 💬
 [2] TPH1, TPH2 💬 D09973 💬 Telotristat [1] 97 💬
359 Metabolic pathways 💬
 [1] TPO 💬 D00401 💬 Methimazole [1] 50 💬
360 Metabolic pathways 💬
 [1] TYMS 💬 D01244 💬 Tegafur [1] 46 💬
361 Metabolic pathways 💬
 [1] UGCG 💬 D09893 💬 Eliglustat [1] 19 💬
362 Metabolic pathways 💬
 [1] UGCG 💬 D11439 💬 Lucerastat [1] 19 💬
363 Metabolic pathways 💬
 [1] UGCG 💬 D05032 💬 Miglustat [3] 19, 256, 299 💬
364 Metabolic pathways 💬
 [1] UGCG 💬 D11633 💬 Venglustat [3]  6 , 19, 67 💬
365 Metabolic pathways 💬
 [1] VKORC1 💬 D08354 💬 Phenindione [1] 65 💬
366 Metabolic pathways 💬
 [1] XDH 💬 D00224 💬 Allopurinol [7]  6 , 46, 57, 60, 66, 96, 97 💬
367 Metabolic pathways 💬
 [1] XDH 💬 D01206 💬 Febuxostat [3]  2 ,  6 , 13 💬
368 Metabolism of xenobiotics by cytochrome P450 💬
 [3] ADH1A, ADH1B, ADH1C 💬 D00707 💬 Fomepizole [1] 301 💬
369 MicroRNAs in cancer 💬
 [1] ABL1 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
370 MicroRNAs in cancer 💬
 [1] ABL1 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
371 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
372 MicroRNAs in cancer 💬
 [3] ABL1, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
373 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRB 💬 D03658 💬 Dasatinib [2] 51, 85 💬
374 MicroRNAs in cancer 💬
 [2] ABL1, PDGFRB 💬 D06414 💬 Dasatinib [2] 51, 85 💬
375 MicroRNAs in cancer 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
376 MicroRNAs in cancer 💬
 [1] CDK6 💬 D10688 💬 Abemaciclib [1] 34 💬
377 MicroRNAs in cancer 💬
 [3] DNMT1, DNMT3A, DNMT3B 💬 D03665 💬 Decitabine [3] 13, 60, 63 💬
378 MicroRNAs in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
379 MicroRNAs in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
380 MicroRNAs in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
381 MicroRNAs in cancer 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
382 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
383 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 D08950 💬 Neratinib [1] 34 💬
384 MicroRNAs in cancer 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
385 MicroRNAs in cancer 💬
 [1] FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
386 MicroRNAs in cancer 💬
 [3] FGFR3, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
387 MicroRNAs in cancer 💬
 [4] HDAC1, HDAC2, HDAC4, HDAC5 💬 D06320 💬 Vorinostat [2] 75, 96 💬
388 MicroRNAs in cancer 💬
 [1] HMOX1 💬 D05922 💬 Stannsoporfin [1] 254 💬
389 MicroRNAs in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
390 MicroRNAs in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
391 MicroRNAs in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
392 MicroRNAs in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
393 MicroRNAs in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
394 MicroRNAs in cancer 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
395 MicroRNAs in cancer 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
396 MicroRNAs in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
397 MicroRNAs in cancer 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
398 MicroRNAs in cancer 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
399 MicroRNAs in cancer 💬
 [2] PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib [2] 28, 34 💬
400 MicroRNAs in cancer 💬
 [2] PDGFRB, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
401 MicroRNAs in cancer 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
402 MicroRNAs in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
403 MicroRNAs in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
404 MicroRNAs in cancer 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
405 MicroRNAs in cancer 💬
 [1] PRKCE 💬 D09671 💬 Sotrastaurin [1] 97 💬
406 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
407 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
408 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
409 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
410 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
411 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
412 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
413 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
414 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
415 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
416 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
417 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
418 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
419 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
420 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
421 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
422 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
423 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
424 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
425 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
426 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
427 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
428 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
429 MicroRNAs in cancer 💬
 [1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
430 MicroRNAs in cancer 💬
 [1] ROCK1 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
431 MicroRNAs in cancer 💬
 [1] TGFB2 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬
432 MicroRNAs in cancer 💬
 [1] VEGFA 💬 D09574 💬 Aflibercept [2] 90, 166 💬
433 MicroRNAs in cancer 💬
 [1] VEGFA 💬 D06409 💬 Bevacizumab [6] 13, 34, 85, 87, 227, 280 💬
434 MicroRNAs in cancer 💬
 [1] VEGFA 💬 D05697 💬 Ranibizumab [4] 34, 166, 227, 301 💬
435 Mineral absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
436 Mineral absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
437 Mineral absorption 💬
 [1] CLCN2 💬 D04790 💬 Lubiprostone [4]  6 , 13, 290, 299 💬
438 Mineral absorption 💬
 [2] HMOX1, HMOX2 💬 D05922 💬 Stannsoporfin [1] 254 💬
439 Mineral absorption 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
440 Mineral absorption 💬
 [1] VDR 💬 D00122 💬 Calcifediol [2] 113, 299 💬
441 Mineral absorption 💬
 [1] VDR 💬 D01125 💬 Calcipotriol [2] 36, 51 💬
442 Mineral absorption 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
443 Mineral absorption 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
444 Mineral absorption 💬
 [1] VDR 💬 D00299 💬 Dihydrotachysterol [2]  6 , 85 💬
445 Mineral absorption 💬
 [1] VDR 💬 D07578 💬 Eldecalcitol [1] 46 💬
446 Mineral absorption 💬
 [1] VDR 💬 D00187 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
447 Mineral absorption 💬
 [1] VDR 💬 D00930 💬 Paricalcitol [5] 19, 66, 218, 238, 298 💬
448 Mitophagy - animal 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
449 Mitophagy - animal 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
450 Mitophagy - animal 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
451 Mitophagy - animal 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
452 Mitophagy - animal 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
453 Morphine addiction 💬
 [1] ADORA1 💬 D00045 💬 Adenosine [3] 13, 58, 65 💬
454 Morphine addiction 💬
 [1] ADORA1 💬 D02769 💬 Adenosine phosphate [1] 46 💬
455 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00227 💬 Aminophylline [1] 63 💬
456 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D00371 💬 Theophylline [2] 236, 299 💬
457 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D06103 💬 Theophylline [2] 236, 299 💬
458 Morphine addiction 💬
 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
459 Morphine addiction 💬
 [9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
460 Morphine addiction 💬
 [1] CACNA1B 💬 D01173 💬 Cilnidipine [1] 67 💬
461 Morphine addiction 💬
 [1] DRD1 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
462 Morphine addiction 💬
 [1] DRD1 💬 D09886 💬 Dexpramipexole [1]  2  💬
463 Morphine addiction 💬
 [1] DRD1 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
464 Morphine addiction 💬
 [1] DRD1 💬 D01044 💬 Flupentixol [1] 97 💬
465 Morphine addiction 💬
 [1] DRD1 💬 D11839 💬 Foslevodopa [1]  6  💬
466 Morphine addiction 💬
 [1] DRD1 💬 D00059 💬 Levodopa [6]  6 , 17, 90, 140, 164, 201 💬
467 Morphine addiction 💬
 [1] DRD1 💬 D08339 💬 Pergolide [1]  6  💬
468 Morphine addiction 💬
 [1] DRD1 💬 D11431 💬 Tavapadon [1]  6  💬
469 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 D09791 💬 Arbaclofen [2] 13, 206 💬
470 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 D08861 💬 Arbaclofen Placarbil [1] 13 💬
471 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬
472 Morphine addiction 💬
 [2] GABBR1, GABBR2 💬 D12240 💬 Valiloxybate [1]  6  💬
473 Morphine addiction 💬
 [1] GABRA1 💬 D00548 💬 Etomidate [1]  6  💬
474 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
475 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D11149 💬 Brexanolone [1] 205 💬
476 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D01253 💬 Clobazam [2] 140, 144 💬
477 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00280 💬 Clonazepam [1]  6  💬
478 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D07784 💬 Delorazepam [3]  6 , 46, 97 💬
479 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00293 💬 Diazepam [3] 46, 155, 298 💬
480 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D02624 💬 Eszopiclone [3]  6 , 13, 46 💬
481 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00697 💬 Flumazenil [5]  6 , 13, 17, 18, 206 💬
482 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04282 💬 Gaboxadol [2] 201, 206 💬
483 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D04300 💬 Ganaxolone [4] 145, 152, 158, 206 💬
484 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00365 💬 Lorazepam [1] 36 💬
485 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00550 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
486 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol [9]  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
487 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
488 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D08690 💬 Zolpidem [3]  5 ,  6 , 46 💬
489 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D01372 💬 Zopiclone [1]  6  💬
490 Morphine addiction 💬
 [2] KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
491 Morphine addiction 💬
 [1] OPRM1 💬 D07132 💬 Buprenorphine [2] 46, 70 💬
492 Morphine addiction 💬
 [1] OPRM1 💬 D00838 💬 Dezocine [1] 46 💬
493 Morphine addiction 💬
 [1] OPRM1 💬 D07831 💬 Dihydrocodeine [1] 310 💬
494 Morphine addiction 💬
 [1] OPRM1 💬 D00320 💬 Fentanyl [3] 46, 70, 215 💬
495 Morphine addiction 💬
 [1] OPRM1 💬 D08047 💬 Hydromorphone [1] 70 💬
496 Morphine addiction 💬
 [1] OPRM1 💬 D08144 💬 Loperamide [2] 13, 97 💬
497 Morphine addiction 💬
 [1] OPRM1 💬 D08233 💬 Morphine [5] 36, 46, 70, 85, 86 💬
498 Morphine addiction 💬
 [1] OPRM1 💬 D08246 💬 Nalbuphine [1] 85 💬
499 Morphine addiction 💬
 [1] OPRM1 💬 D05111 💬 Nalmefene [1]  6  💬
500 Morphine addiction 💬
 [1] OPRM1 💬 D08249 💬 Naloxone [2]  6 , 226 💬
501 Morphine addiction 💬
 [1] OPRM1 💬 D05113 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
502 Morphine addiction 💬
 [1] OPRM1 💬 D05312 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬
503 Morphine addiction 💬
 [1] OPRM1 💬 D08323 💬 Oxymorphone [1] 70 💬
504 Morphine addiction 💬
 [1] OPRM1 💬 D08473 💬 Remifentanil [2]  6 , 70 💬
505 Morphine addiction 💬
 [1] OPRM1 💬 D05938 💬 Sufentanil [2] 70, 280 💬
506 Morphine addiction 💬
 [1] OPRM1 💬 D08623 💬 Tramadol [5] 46, 70, 78, 226, 271 💬
507 Morphine addiction 💬
 [1] OPRM1 💬 D08639 💬 Trimebutine [1] 51 💬
508 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07546 💬 Bucladesine [1] 246 💬
509 Morphine addiction 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 D07961 💬 Flavoxate [1] 226 💬
510 Morphine addiction 💬
 [2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 46, 51, 70 💬
511 Morphine addiction 💬
 [2] PDE3A, PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
512 Morphine addiction 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
513 Morphine addiction 💬
 [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
514 Morphine addiction 💬
 [1] PDE4A 💬 D00302 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬
515 Morphine addiction 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬
516 Morphine addiction 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [4] 84, 97, 206, 299 💬
517 Morphine addiction 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
518 Morphine addiction 💬
 [1] PDE4D 💬 D12173 💬 Zatolmilast [1] 206 💬
519 Morphine addiction 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
520 mTOR signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
521 mTOR signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
522 mTOR signaling pathway 💬
 [1] IGF1R 💬 D09925 💬 Linsitinib [1] 232 💬
523 mTOR signaling pathway 💬
 [1] IGF1R 💬 D03297 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
524 mTOR signaling pathway 💬
 [1] IGF1R 💬 D09680 💬 Teprotumumab [1] 51 💬
525 mTOR signaling pathway 💬
 [1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
526 mTOR signaling pathway 💬
 [1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
527 mTOR signaling pathway 💬
 [1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
528 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
529 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
530 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
531 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
532 mTOR signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
533 mTOR signaling pathway 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
534 mTOR signaling pathway 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
535 mTOR signaling pathway 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
536 mTOR signaling pathway 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
537 mTOR signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
538 mTOR signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
539 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
540 mTOR signaling pathway 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
541 mTOR signaling pathway 💬
 [1] TNF 💬 D02597 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
542 mTOR signaling pathway 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
543 mTOR signaling pathway 💬
 [1] TNF 💬 D00742 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
544 mTOR signaling pathway 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
545 mTOR signaling pathway 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
546 mTOR signaling pathway 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
547 mTOR signaling pathway 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
548 mTOR signaling pathway 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
549 mTOR signaling pathway 💬
 [1] TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
550 mTOR signaling pathway 💬
 [1] TNF 💬 D08976 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬
551 mTOR signaling pathway 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬

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