Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alanine, aspartate and glutamate metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
2	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00146 💬	Corticotropin	[12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
3	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
4	Amyotrophic lateral sclerosis 💬	[1] SIGMAR1 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
5	beta-Alanine metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
6	Butanoate metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
7	Calcium signaling pathway 💬	[2] HTR2A, HTR2C 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
8	cAMP signaling pathway 💬	[1] HTR1D 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
9	cAMP signaling pathway 💬	[1] MC2R 💬	D00146 💬	Corticotropin	[12] 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
10	cAMP signaling pathway 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬

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