Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Aldosterone synthesis and secretion 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

Amyotrophic lateral sclerosis 💬

[1] SIGMAR1 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Calcium signaling pathway 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

Calcium signaling pathway 💬

[2] HTR2A, HTR2C 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

cAMP signaling pathway 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

cAMP signaling pathway 💬

[1] HTR1D 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Circadian entrainment 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

Cortisol synthesis and secretion 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

Cushing syndrome 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

ECM-receptor interaction 💬

[1] SV2A 💬

Brivaracetam 💬

Brivaracetam

[2] 149, 309 💬

ECM-receptor interaction 💬

[3] SV2A, SV2B, SV2C 💬

Padsevonil 💬

Padsevonil

[1] 149 💬

Estrogen signaling pathway 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

GABAergic synapse 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Gap junction 💬

[2] HTR2A, HTR2C 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

GnRH secretion 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

GnRH secretion 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Inflammatory mediator regulation of TRP channels 💬

[2] HTR2A, HTR2C 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Insulin secretion 💬

[1] SNAP25 💬

Botulinum toxin type A 💬

Botulinum toxin type A

[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
7	Corticobasal degeneration;Corticobasal syndrome;CBD;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
17	Multiple system atrophy;MSA-C;MSA-P;
36	Epidermolysis bullosa;
47	Buerger disease;Thromboangiitis obliterans;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

MAPK signaling pathway 💬

[3] CACNA1G, CACNA1H, CACNA1I 💬

Flunarizine 💬

Flunarizine

[1] 149 💬

Morphine addiction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Neuroactive ligand-receptor interaction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Neuroactive ligand-receptor interaction 💬

[3] HTR1D, HTR2A, HTR2C 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Pathways of neurodegeneration - multiple diseases 💬

[1] SIGMAR1 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Serotonergic synapse 💬

[4] HTR1D, HTR2A, HTR2C, SLC6A4 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Synaptic vesicle cycle 💬

[1] SLC6A4 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Synaptic vesicle cycle 💬

[1] SNAP25 💬

Botulinum toxin type A 💬

Botulinum toxin type A

[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
5	Progressive supranuclear palsy;PSP;
6	Parkinson disease;Disease Parkinson's;
7	Corticobasal degeneration;Corticobasal syndrome;CBD;
13	Multiple sclerosis/Neuromyelitis optica;
15	Inclusion body myositis;
17	Multiple system atrophy;MSA-C;MSA-P;
36	Epidermolysis bullosa;
47	Buerger disease;Thromboangiitis obliterans;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
113	Muscular dystrophy;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Taste transduction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Taste transduction 💬

[1] HTR1D 💬

Fenfluramine 💬

Fenfluramine

[4] 140, 144, 145, 149 💬

Disease ID	Name
140	Dorabe syndrome;Dravet syndrome;
144	Lennox-Gastaut syndrome;
145	West syndrome;Infantile spasm;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;

Taste transduction 💬

[2] SCN3A, SCN9A 💬

Lacosamide 💬

Lacosamide

[4] 2 , 46, 149, 298 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
298	Hereditary pancreatitis;Chronic pancreatitis;

Type II diabetes mellitus 💬

[1] CACNA1G 💬

Flunarizine 💬

Flunarizine

[1] 149 💬