Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
2 AMPK signaling pathway 💬
[1] ADRA1A 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
3 Calcium signaling pathway 💬
[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
4 cAMP signaling pathway 💬
[2] ADRB1, ADRB2 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
5 cGMP-PKG signaling pathway 💬
[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
6 Chemical carcinogenesis - receptor activation 💬
[3] ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
7 Dilated cardiomyopathy 💬
[1] ADRB1 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
8 Gap junction 💬
[1] ADRB1 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
9 Neuroactive ligand-receptor interaction 💬
[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
10 Regulation of lipolysis in adipocytes 💬
[3] ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
11 Renin secretion 💬
[3] ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
12 Salivary secretion 💬
[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
13 Thermogenesis 💬
[1] ADRB3 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
14 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬