DDrare
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Showing 1 to 10 of 25 entries
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KEGG PATHWAY
On map,
Yellow:
Drug target,
Red:
All disease-related
KEGG GENES
KEGG DRUG
DrugBank
Disease ID
1
Calcium signaling pathway
💬
Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare
EDNRA
[2]
EDNRA
,
EDNRB
💬
D01227
D01227
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
2
Calcium signaling pathway
💬
Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare
EDNRA
[2]
EDNRA
,
EDNRB
💬
D07538
D07538
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
3
cAMP signaling pathway
💬
Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare
EDNRA
[1]
EDNRA
💬
D01227
D01227
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
4
cAMP signaling pathway
💬
Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare
EDNRA
[1]
EDNRA
💬
D07538
D07538
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
5
cGMP-PKG signaling pathway
💬
Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare
ADRA2A
[3]
ADRA2A
,
ADRA2B
,
ADRA2C
💬
D00514
D00514
💬
Dexmedetomidine
002
[14]
2
,
4
,
6
,
21
,
34
,
46
,
70
,
107
,
113
,
171
,
212
,
215
,
226
,
280
💬
6
cGMP-PKG signaling pathway
💬
Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare
EDNRA
[2]
EDNRA
,
EDNRB
💬
D01227
D01227
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
7
cGMP-PKG signaling pathway
💬
Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare
EDNRA
[2]
EDNRA
,
EDNRB
💬
D07538
D07538
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
8
cGMP-PKG signaling pathway
💬
Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare
PDE5A
[1]
PDE5A
💬
D08514
D08514
💬
Sildenafil
006
[17]
6
,
46
,
50
,
51
,
85
,
86
,
90
,
113
,
210
,
211
,
212
,
225
,
226
,
278
,
294
,
299
,
301
💬
9
Melanogenesis
💬
Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare
EDNRB
[1]
EDNRB
💬
D01227
D01227
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
10
Melanogenesis
💬
Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare
EDNRB
[1]
EDNRB
💬
D07538
D07538
💬
Bosentan
041
[10]
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
💬
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