Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alcoholism 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
2	Alcoholism 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
3	Alzheimer disease 💬	[1] MAPT 💬	D11210 💬	Flortaucipir	[3] 5 , 7 , 127 💬
4	Amphetamine addiction 💬	[1] DRD1 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
5	Amphetamine addiction 💬	[1] DRD1 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
6	Axon guidance 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
7	Calcium signaling pathway 💬	[1] DRD1 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
8	Calcium signaling pathway 💬	[2] DRD1, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
9	cAMP signaling pathway 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
10	cAMP signaling pathway 💬	[3] DRD1, DRD2, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
11	cAMP signaling pathway 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
12	cGMP-PKG signaling pathway 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
13	Chemokine signaling pathway 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
14	Cocaine addiction 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
15	Cocaine addiction 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
16	Dopaminergic synapse 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
17	Dopaminergic synapse 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
18	Focal adhesion 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
19	Gap junction 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
20	Gap junction 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
21	Human cytomegalovirus infection 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
22	Insulin secretion 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
23	Leukocyte transendothelial migration 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
24	Lipid and atherosclerosis 💬	[1] ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
25	MAPK signaling pathway 💬	[1] MAPT 💬	D11210 💬	Flortaucipir	[3] 5 , 7 , 127 💬
26	MicroRNAs in cancer 💬	[1] ROCK1 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
27	Morphine addiction 💬	[1] DRD1 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
28	Morphine addiction 💬	[1] DRD1 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
29	Neuroactive ligand-receptor interaction 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
30	Neuroactive ligand-receptor interaction 💬	[5] DRD1, DRD2, DRD3, DRD4, DRD5 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
31	Oxytocin signaling pathway 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
32	Parkinson disease 💬	[2] DRD1, DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
33	Parkinson disease 💬	[2] DRD1, DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
34	Parkinson disease 💬	[1] MAPT 💬	D11210 💬	Flortaucipir	[3] 5 , 7 , 127 💬
35	Pathogenic Escherichia coli infection 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
36	Pathways in cancer 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
37	Pathways of neurodegeneration - multiple diseases 💬	[1] MAPT 💬	D11210 💬	Flortaucipir	[3] 5 , 7 , 127 💬
38	Platelet activation 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
39	Proteoglycans in cancer 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
40	Rap1 signaling pathway 💬	[1] DRD2 💬	D07460 💬	Apomorphine	[3] 5 , 6 , 7 💬
41	Rap1 signaling pathway 💬	[1] DRD2 💬	D07870 💬	Dopamine	[4] 6 , 7 , 74, 299 💬
42	Regulation of actin cytoskeleton 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
43	Salmonella infection 💬	[1] ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
44	Shigellosis 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
45	Sphingolipid signaling pathway 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
46	Synaptic vesicle cycle 💬	[1] SNAP25 💬	D00783 💬	Botulinum toxin type A	[14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
47	TGF-beta signaling pathway 💬	[1] ROCK1 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
48	Tight junction 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
49	Vascular smooth muscle contraction 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
50	Wnt signaling pathway 💬	[1] ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
51	Yersinia infection 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬