Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C1R [3] C1R, C1S, KLKB1 💬 |
D10845 D10845 💬 |
Conestat alfa | 061 [1] 61 💬 |
2 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C1S [1] C1S 💬 |
D11530 D11530 💬 |
Sutimlimab | 061 [1] 61 💬 |
3 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C3 [1] C3 💬 |
D11613 D11613 💬 |
Pegcetacoplan | 002 [4] 2 , 61, 62, 222 💬 |
4 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 [2] 62, 109 💬 |
5 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
6 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 |
7 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D11477 D11477 💬 |
Pozelimab | 011 [2] 11, 62 💬 |
8 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 |
9 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D11838 D11838 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 |
10 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5 [1] C5 💬 |
D12357 D12357 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 |
11 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [3] 43, 44, 222 💬 |
12 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
CFB [1] CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 [5] 61, 62, 66, 109, 222 💬 |
13 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
CFD [1] CFD 💬 |
D11641 D11641 💬 |
Danicopan | 062 [1] 62 💬 |
14 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F10 [1] F10 💬 |
D03213 D03213 💬 |
Apixaban | 222 [1] 222 💬 |
15 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F10 [1] F10 💬 |
D09710 D09710 💬 |
Edoxaban | 046 [2] 46, 88 💬 |
16 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F10 [1] F10 💬 |
D07086 D07086 💬 |
Rivaroxaban | 046 [4] 46, 49, 91, 210 💬 |
17 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F10 [2] F10, F9 💬 |
D10821 D10821 💬 |
Emicizumab | 288 [1] 288 💬 |
18 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 |
19 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F2 [1] F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 |
20 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F2 [1] F2 💬 |
D06410 D06410 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 |
21 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
F8 [1] F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 [6] 6 , 64, 72, 75, 225, 288 💬 |
22 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [4] 64, 66, 109, 222 💬 |
23 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
PLG [1] PLG 💬 |
D00160 D00160 💬 |
Aminocaproic acid | 070 [1] 70 💬 |
24 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
PLG [1] PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 [7] 46, 70, 215, 227, 274, 288, 299 💬 |
25 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Enoxaparin | 046 [1] 46 💬 |
26 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 047 [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
27 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 [1] SERPINC1 💬 |
D07510 D07510 💬 |
Parnaparin | 097 [1] 97 💬 |
28 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
SERPINC1 [2] SERPINC1, SERPIND1 💬 |
D08547 D08547 💬 |
Sulodexide | 051 [2] 51, 271 💬 |
29 | Complement and coagulation cascades 💬 Related to 17 target genes, 29 drugs (DrugBank) and 44 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |