Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
APOC3 [1] APOC3 💬 |
D11648 D11648 💬 |
Volanesorsen | 265 [1] 265 💬 |
2 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
CPT1A [4] CPT1A, CPT1B, CPT1C, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
3 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARA [1] PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 |
4 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARA [1] PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 [2] 93, 94 💬 |
5 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARA [1] PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 [6] 8 , 79, 93, 94, 97, 265 💬 |
6 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARA [1] PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 [1] 93 💬 |
7 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D12242 D12242 💬 |
Bocidelpar | 113 [1] 113 💬 |
8 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 [1] 20 💬 |
9 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 [17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
10 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 [5] 46, 75, 97, 222, 265 💬 |
11 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
PPARG [1] PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 [2] 93, 94 💬 |
12 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02754 D02754 💬 |
Acitretin | 037 [1] 37 💬 |
13 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 [1] 49 💬 |
14 | PPAR signaling pathway 💬 Related to 10 target genes, 14 drugs (DrugBank) and 32 diseases in DDrare |
RXRA [3] RXRA, RXRB, RXRG 💬 |
D03106 D03106 💬 |
Bexarotene | 013 [2] 13, 75 💬 |