Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Parathyroid hormone synthesis, secretion and action 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Parathyroid hormone synthesis, secretion and action 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
3 Parathyroid hormone synthesis, secretion and action 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
4 Parathyroid hormone synthesis, secretion and action 💬
 [1] CASR 💬 D03504 💬 Cinacalcet [1] 238 💬
5 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
6 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
7 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
8 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
9 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
10 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
11 Parathyroid hormone synthesis, secretion and action 💬
 [1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
12 Parathyroid hormone synthesis, secretion and action 💬
 [1] FGF23 💬 D10913 💬 Burosumab [1] 238 💬
13 Parathyroid hormone synthesis, secretion and action 💬
 [1] FGFR1 💬 D11589 💬 Infigratinib [1] 276 💬
14 Parathyroid hormone synthesis, secretion and action 💬
 [1] FGFR1 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
15 Parathyroid hormone synthesis, secretion and action 💬
 [1] MAP2K1 💬 D10604 💬 Binimetinib [1] 34 💬
16 Parathyroid hormone synthesis, secretion and action 💬
 [1] MAP2K1 💬 D10405 💬 Cobimetinib [1] 280 💬
17 Parathyroid hormone synthesis, secretion and action 💬
 [1] MAP2K1 💬 D11675 💬 Mirdametinib [1] 34 💬
18 Parathyroid hormone synthesis, secretion and action 💬
 [1] MAP2K1 💬 D09666 💬 Selumetinib [1] 34 💬
19 Parathyroid hormone synthesis, secretion and action 💬
 [1] MAP2K1 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
20 Parathyroid hormone synthesis, secretion and action 💬
 [1] MMP13 💬 D08859 💬 Apratastat [1] 46 💬
21 Parathyroid hormone synthesis, secretion and action 💬
 [1] PDE4A 💬 D00302 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬
22 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D00227 💬 Aminophylline [1] 63 💬
23 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬
24 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D07546 💬 Bucladesine [1] 246 💬
25 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
26 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
27 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate [1] 226 💬
28 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
29 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [4] 84, 97, 206, 299 💬
30 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
31 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D00371 💬 Theophylline [2] 236, 299 💬
32 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D06103 💬 Theophylline [2] 236, 299 💬
33 Parathyroid hormone synthesis, secretion and action 💬
 [1] PDE4D 💬 D12173 💬 Zatolmilast [1] 206 💬
34 Parathyroid hormone synthesis, secretion and action 💬
 [1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
35 Parathyroid hormone synthesis, secretion and action 💬
 [1] PTH1R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
36 Parathyroid hormone synthesis, secretion and action 💬
 [1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
37 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin [1] 37 💬
38 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin [1] 49 💬
39 Parathyroid hormone synthesis, secretion and action 💬
 [3] RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene [2] 13, 75 💬
40 Parathyroid hormone synthesis, secretion and action 💬
 [1] SOST 💬 D10156 💬 Romosozumab [1] 274 💬
41 Parathyroid hormone synthesis, secretion and action 💬
 [1] TNFSF11 💬 D03684 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
42 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
43 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00122 💬 Calcifediol [2] 113, 299 💬
44 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D01125 💬 Calcipotriol [2] 36, 51 💬
45 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
46 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00188 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
47 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00299 💬 Dihydrotachysterol [2]  6 , 85 💬
48 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D07578 💬 Eldecalcitol [1] 46 💬
49 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00187 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
50 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 D00930 💬 Paricalcitol [5] 19, 66, 218, 238, 298 💬