Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Steroid hormone biosynthesis 💬	[1] COMT 💬	D00781 💬	Entacapone	[2] 6 , 17 💬
2	Steroid hormone biosynthesis 💬	[1] COMT 💬	D10825 💬	Opicapone	[1] 6 💬
3	Steroid hormone biosynthesis 💬	[1] COMT 💬	D00786 💬	Tolcapone	[3] 6 , 28, 127 💬
4	Steroid hormone biosynthesis 💬	[3] CYP11A1, CYP11B1, CYP17A1 💬	D10950 💬	Levoketoconazole	[1] 75 💬
5	Steroid hormone biosynthesis 💬	[1] CYP11B1 💬	D00410 💬	Metyrapone	[1] 75 💬
6	Steroid hormone biosynthesis 💬	[1] CYP11B2 💬	D11061 💬	Osilodrostat	[1] 75 💬
7	Steroid hormone biosynthesis 💬	[1] CYP17A1 💬	D00351 💬	Ketoconazole	[3] 8 , 13, 75 💬
8	Steroid hormone biosynthesis 💬	[1] CYP19A1 💬	D00960 💬	Anastrozole	[3] 78, 86, 193 💬
9	Steroid hormone biosynthesis 💬	[1] CYP19A1 💬	D00964 💬	Letrozole	[2] 81, 89 💬
10	Steroid hormone biosynthesis 💬	[2] SRD5A1, SRD5A2 💬	D03820 💬	Dutasteride	[2] 1 , 2 💬

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