Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Autoimmune thyroid disease 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
2	Autoimmune thyroid disease 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
3	Autoimmune thyroid disease 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
4	Autoimmune thyroid disease 💬	[1] CD40LG 💬	D06193 💬	Toralizumab	[1] 63 💬
5	Autoimmune thyroid disease 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271 ...
6	Autoimmune thyroid disease 💬	[2] CD80, CD86 💬	D03222 💬	Belatacept	[1] 46 💬
7	Autoimmune thyroid disease 💬	[1] CTLA4 💬	D04603 💬	Ipilimumab	[1] 159 💬
8	Autoimmune thyroid disease 💬	[1] CTLA4 💬	D06657 💬	Tremelimumab	[1] 96 💬
9	Autoimmune thyroid disease 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09662 💬	Rontalizumab	[1] 49 💬
10	Autoimmune thyroid disease 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 ...	D09668 💬	Sifalimumab	[1] 49 💬

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