Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Oxygen 1件: Oxygen3件: Medical air; Nitrogen; Oxygen; --20件: 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
2 Oxytocin 1件: Oxytocin2件: OXYTOCIN; Syntocinon; 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬6件: 6, 72, 127, 193, 206, 226
3 Corticotropin 1件: Corticotropin5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬15件: 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
4 Acetylcysteine 1件: Acetylcysteine3件: Acetylcysteine; Mucomyst; N-acetylcysteine; --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
5 Diazoxide 1件: Diazoxide1件: Diazoxide; 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬2件: 13, 193
6 Metyrapone 1件: Metyrapone2件: Metopirone; METYRAPONE; 1件: CYP11B1 💬4件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis 💬2件: 75, 193
7 Octreotide 1件: Octreotide3件: Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR; 1件: SSTR2 💬4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬7件: 67, 75, 84, 85, 89, 193, 227
8 Topiramate 1件: Topiramate2件: TOPAMAX; Topiramate; 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
9 Metoprolol tartrate 1件: Metoprolol2件: Metoprolol; METOPROLOL SUCCINATE; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
10 Guanfacine hydrochloride 1件: Guanfacine1件: Guanfacine; 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
11 Sirolimus 1件: Sirolimus3件: RAPAMUNE; Rapamycin; SIROLIMUS; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
12 Anastrozole 1件: Anastrozole2件: Anastrozole; Arimidex; 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
13 Ubidecarenone 1件: Ubidecarenone3件: Coenzyme Q-10; Coenzyme Q10; CoQ10; --13件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
14 Sodium chloride 1件: Sodium chloride6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; SPORANOX; --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
15 Metoprolol 1件: Metoprolol2件: Metoprolol; METOPROLOL SUCCINATE; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
16 Somatropin 1件: Somatotropin17件: Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
17 Exenatide 1件: Exenatide3件: BYDUREON; Byetta; Exenatide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
18 Metoprolol fumarate 1件: Metoprolol2件: Metoprolol; Metoprolol succinate; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
19 Metyrapone tartrate 1件: Metyrapone2件: Metopirone; METYRAPONE; 1件: CYP11B1 💬4件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis 💬2件: 75, 193
20 Rimonabant 1件: Rimonabant2件: Acomplia; Rimonabant; 1件: CNR1 💬4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193
21 Liraglutide 1件: Liraglutide2件: LIRAGLUTIDE; Saxenda; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193
22 Octreotide acetate 1件: Octreotide3件: OCTREOTIDE; OCTREOTIDE ACETATE; Sandostatin LAR; 1件: SSTR2 💬4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬7件: 67, 75, 84, 85, 89, 193, 227
23 Carbetocin 1件: Carbetocin1件: Carbetocin; 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193
24 Choline 1件: Choline1件: Choline; --4件: 93, 171, 193, 299
25 Guanfacine 1件: Guanfacine1件: Guanfacine; 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
26 Pitolisant 1件: Pitolisant1件: Pitolisant; 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193
27 Cannabidiol 1件: Cannabidiol3件: Cannabidiol; Epidyolex; Sativex; 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271