Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MAPK14 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
2 MAPK14 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
3 IGF1R 7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
4 IGF1R 7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
5 IGF1R 7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09680 Teprotumumab 1件: 51
6 IGF1R 7件: Ras signaling pathway, Rap1 signaling pathway, Signaling pathways regulating pluripotency of stem cells, Progesterone-mediated oocyte maturation, Transcriptional misregulation in cancer, Proteoglycans in cancer, Prostate cancer D09925 Linsitinib 1件: 232
7 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D00227 Aminophylline 1件: 63
8 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D00371 Theophylline 2件: 236, 299
9 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D00417 Milrinone 1件: 294
10 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D00528 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
11 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D00718 Flavoxate 1件: 226
12 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D01385 Ibudilast 2件: 2, 13
13 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D01453 Caffeine 9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
14 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D01712 Theophylline 2件: 236, 299
15 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D01896 Cilostazol 3件: 51, 70, 124
16 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D02017 Theophylline 2件: 236, 299
17 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D02085 Milrinone 1件: 294
18 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D04720 Levosimendan 1件: 2
19 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D05429 Aminophylline 1件: 63
20 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D06103 Theophylline 2件: 236, 299
21 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D06104 Theophylline 2件: 236, 299
22 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D07546 Bucladesine 1件: 246
23 PDE3B 4件: Purine metabolism, Progesterone-mediated oocyte maturation, Regulation of lipolysis in adipocytes, Renin secretion D07961 Flavoxate 1件: 226
24 PGR 1件: Progesterone-mediated oocyte maturation D00066 Progesterone 1件: 76
25 PGR 1件: Progesterone-mediated oocyte maturation D00182 Norethisterone 4件: 13, 46, 49, 299
26 PGR 1件: Progesterone-mediated oocyte maturation D00289 Danazol 5件: 60, 63, 64, 65, 285
27 PGR 1件: Progesterone-mediated oocyte maturation D00585 Mifepristone 1件: 75
28 PGR 1件: Progesterone-mediated oocyte maturation D00950 Levonorgestrel 1件: 13
29 PGR 1件: Progesterone-mediated oocyte maturation D00951 Medroxyprogesterone acetate 6件: 13, 35, 46, 49, 51, 60
30 PGR 1件: Progesterone-mediated oocyte maturation D00952 Megestrol acetate 1件: 76
31 PGR 1件: Progesterone-mediated oocyte maturation D00953 Norethisterone 4件: 13, 46, 49, 299
32 PGR 1件: Progesterone-mediated oocyte maturation D01217 Dydrogesterone 1件: 13
33 PGR 1件: Progesterone-mediated oocyte maturation D02367 Desogestrel 1件: 230
34 PGR 1件: Progesterone-mediated oocyte maturation D05209 Norgestimate 1件: 299
35 PGR 1件: Progesterone-mediated oocyte maturation D07222 Nomegestrol 1件: 13
36 PGR 1件: Progesterone-mediated oocyte maturation D08166 Medroxyprogesterone acetate 6件: 13, 35, 46, 49, 51, 60
37 PGR 1件: Progesterone-mediated oocyte maturation D08167 Megestrol acetate 1件: 76
38 PGR 1件: Progesterone-mediated oocyte maturation D08281 Nomegestrol acetate 1件: 13
39 PGR 1件: Progesterone-mediated oocyte maturation D09567 Ulipristal 1件: 10
40 PIK3CA 24件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
41 PIK3CB 24件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
42 PIK3CD 24件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
43 PIK3CD 24件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
44 PLK1 1件: Progesterone-mediated oocyte maturation D10154 Rigosertib 1件: 36
45 MAPK11 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
46 MAPK11 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
47 MAPK13 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
48 MAPK13 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
49 MAP2K1 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D09666 Selumetinib 1件: 34
50 MAP2K1 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
51 MAP2K1 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10405 Cobimetinib 1件: 280
52 MAP2K1 21件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10604 Binimetinib 1件: 34
53 RAF1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D06272 Sorafenib 2件: 34, 86
54 RAF1 18件: Ras signaling pathway, Rap1 signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer D08524 Sorafenib 2件: 34, 86
55 MAPK12 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D09639 Losmapimod 2件: 113, 222
56 MAPK12 21件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Retrograde endocannabinoid signaling, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Proteoglycans in cancer D10959 Neflamapimod 1件: 8
57 BRAF 9件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D06272 Sorafenib 2件: 34, 86
58 BRAF 9件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D08524 Sorafenib 2件: 34, 86
59 BRAF 9件: Rap1 signaling pathway, Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Progesterone-mediated oocyte maturation, Proteoglycans in cancer, Renal cell carcinoma, Prostate cancer, Thyroid cancer D10064 Dabrafenib 1件: 34