Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetic acid, glacial [1] Acetic acid[1] Acetic acid; --[1] 97
2 Alanine [1] Alanine[2] Alanine; L-alanine; --[5] 6, 13, 251, 298, 299
3 Aspartic acid -[0] ---
4 Ascorbic acid [1] Ascorbic acid[4] Acidum ascorbicum; Ascorbic Acid; Iron; Vitamin C; --[8] 10, 97, 192, 206, 210, 211, 212, 298
5 Adenine [1] Adenine[1] Adenin; --[1] 46
6 Adenosine [1] Adenosine[2] Adenosine; Ginseng; [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65
7 Anhydrous lactose [1] Lactose[1] Lactose; --[6] 2, 6, 13, 97, 228, 310
8 Androstenedione -[0] ---
9 Alcohol [1] Ethanol[3] Alcohol; Ethanol; Prednisone; --[7] 13, 51, 58, 97, 279, 280, 298
10 Aspirin [1] Acetylsalicylic acid[2] Acetylsalicylic Acid; Aspirin; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
11 Atropine [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
12 Allantoin [1] Allantoin[1] ALLANTOIN; --[1] 36
13 Albendazole [1] Albendazole[2] Albendazole; Eskazole; --[12] 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
14 Angiotensin II [1] Angiotensin II[2] Angiotensin; Angiotensin II; [2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224
15 Aminocaproic acid [1] Aminocaproic acid[2] Aminocaproic acid; EACA; [1] PLG 💬[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[1] 70
16 Aminosalicylic acid [1] Aminosalicylic acid[2] 4-Aminosalicylic acid; AMINOSALICYLIC ACID; --[3] 13, 96, 97
17 Androstenediol -[0] ---
18 Alprostadil [1] Alprostadil[1] Alprostadil; [1] PTGER1 💬[4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[2] 51, 70
19 Argatroban -[0] ---
20 Ajmaline -[0] ---
21 Amphotericin B [1] Amphotericin B[2] ABELCET; Amphotericin B; --[1] 299
22 Ampicillin [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
23 Acarbose [1] Acarbose[1] Acarbose; [5] AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		[7] Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬[1] 298
24 Acetaminophen [1] Acetaminophen[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
25 Acetazolamide [1] Acetazolamide[1] Acetazolamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 86, 90, 115, 154, 155, 225, 230
26 Acetohexamide -[0] ---
27 Acetohydroxamic acid [1] Acetohydroxamic acid[1] Acetohydroxamic Acid; --[2] 6, 251
28 Acetylcysteine [1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-Acetylcysteine; --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
29 Acyclovir [1] Acyclovir[3] Aciclovir; Acycloguanosine; Acyclovir; --[5] 13, 28, 46, 53, 60
30 Allopurinol [1] Allopurinol[2] ALLOPURINOL; ALLOPURINOL SODIUM; [1] XDH 💬[5] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Peroxisome, Purine metabolism 💬[6] 6, 46, 57, 66, 96, 97
31 Alprazolam [1] Alprazolam[1] Alprazolam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75
32 Amifostine [1] Amifostine[1] Amifostine; --[1] 28
33 Aminophylline [1] Aminophylline[1] Aminophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63
34 Amoxapine [1] Amoxapine[1] Amoxapine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 46
35 Amoxicillin [1] Amoxicillin[4] Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin; --[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
36 Anisotropine methylbromide -[0] ---
37 Anthralin -[0] ---
38 Astemizole -[0] ---
39 Atenolol [1] Atenolol[1] ATENOLOL; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
40 Atovaquone [1] Atovaquone[1] ATOVAQUONE; --[1] 61
41 Auranofin -[0] ---
42 Azathioprine [1] Azathioprine[3] Azathioprine; Azatioprina; Imuran; --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
43 Aztreonam [1] Aztreonam[2] AZTREONAM; Cayston; --[2] 228, 299
44 Amyl nitrite [1] Amyl Nitrite[1] Amyl Nitrite; [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 58
45 Amobarbital -[0] ---
46 Aminopyrine -[0] ---
47 Aminoglutethimide -[0] ---
48 Acebutolol hydrochloride -[0] ---
49 Amlodipine besylate [1] Amlodipine[1] Amlodipine; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
50 Amiodarone hydrochloride [1] Amiodarone[1] AMIODARONE; [16] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[32] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 28, 127
51 Amiloride hydrochloride [1] Amiloride[3] Amiloride; Amiloride Hydrochloride; Midamor; [3] SCNN1A,
SCNN1B,
SCNN1G 💬		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299
52 Azelastine hydrochloride -[0] ---
53 Azatadine maleate -[0] ---
54 Aprobarbital -[0] ---
55 Aldesleukin [1] Aldesleukin[4] Aldesleukin; ILT-101; Proleukin; Recombinant human interleukin-2; [3] IL2RA,
IL2RB,
IL2RG 💬		[14] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬[6] 2, 35, 49, 65, 96, 97
56 Atracurium besylate -[0] ---
57 Amantadine hydrochloride [1] Amantadine[3] Amantadine; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
58 Acetophenazine maleate -[0] ---
59 Amitriptyline hydrochloride [1] Amitriptyline[3] Amitriptylin; Amitriptyline; Amitriptyline hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299
60 Alfentanil hydrochloride -[0] ---
61 Amikacin sulfate [1] Amikacin[5] AMIKACIN; AMIKACIN SULFATE; Amikacina; Amikacine; Arikayce; --[2] 60, 299
62 Atorvastatin calcium anhydorous [1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Lipitor; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
63 Abacavir sulfate [1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen; --[4] 2, 135, 265, 325
64 Amprenavir [1] Amprenavir[1] Amprenavir; --[1] 265
65 Alendronate sodium [1] Alendronic acid[3] Alendronate; Alendronate sodium; Alendronic acid; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
66 Anastrozole [1] Anastrozole[2] Anastrozole; Arimidex; [1] CYP19A1 💬[3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193
67 Aurothioglucose -[0] ---
68 Ambenonium chloride -[0] ---
69 Apraclonidine hydrochloride [1] Apraclonidine[1] Apraclonidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11
70 Adapalene -[0] ---
71 Ammonium chloride [1] Ammonium chloride[1] Ammonium chloride; --[3] 96, 107, 251
72 Azelnidipine -[0] ---
73 Aripiprazole [1] Aripiprazole[1] Aripiprazole; [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206
74 Alprenolol hydrochloride -[0] ---
75 Acetazolamide sodium [1] Acetazolamide[1] Acetazolamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 86, 90, 115, 154, 155, 225, 230
76 Ampicillin hydrate [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
77 Alclofenac -[0] ---
78 Atazanavir sulfate [1] Atazanavir[2] Atazanavir; Reyataz; --[1] 265
79 Amezinium metilsulfate -[0] ---
80 Azosemide -[0] ---
81 Aprindine hydrochloride -[0] ---
82 Allylestrenol -[0] ---
83 Amcinonide -[0] ---
84 Aminohippurate sodium [1] Aminohippuric acid[1] Aminohippurate; --[4] 49, 53, 67, 86
85 Alminoprofen -[0] ---
86 Alfacalcidol [1] Alfacalcidol[2] Alfacalcidol; One-alpha; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[8] 41, 46, 49, 50, 96, 107, 235, 238
87 Aceclofenac [1] Aceclofenac[1] Aceclofenac; [3] PTGES,
PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
88 Aranidipine -[0] ---
89 Acemetacin -[0] ---
90 Adefovir dipivoxil -[0] ---
91 Alfuzosin hydrochloride [1] Alfuzosin[1] Alfuzosin; [1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13
92 Anecortave acetate -[0] ---
93 Antipyrine -[0] ---
94 Alclometasone dipropionate -[0] ---
95 Amlexanox -[0] ---
96 Aniracetam -[0] ---
97 Apomorphine hydrochloride [1] Apomorphine[3] APOKYN; Apomorfina; Apomorphine; [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
98 Angiotensin II [1] Angiotensin II[2] Angiotensin; Angiotensin II; [2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224
99 Atropine sulfate [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
100 Amphetamine sulfate -[0] ---
101 Arsenic trioxide -[0] ---
102 Ampicillin sodium [1] Ampicillin[1] ABPC; --[5] 2, 6, 13, 84, 299
103 Azithromycin hydrate [1] Azithromycin[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax; --[6] 13, 84, 85, 96, 228, 299
104 Albuterol [1] Salbutamol[3] Albuterol; Salbutamol; Ventolin; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[14] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299
105 Adenosine triphosphate disodium hydrate -[0] ---
106 Amsacrine -[0] ---
107 Apramycin -[0] ---
108 Alginic acid [1] Alginic acid[3] Algin; Alginate; Alginic acid; --[4] 51, 53, 97, 299
109 Acebutolol -[0] ---
110 Azlocillin -[0] ---
111 Anethole -[0] ---
112 Amitraz -[0] ---
113 Aspartame [1] Aspartame[0] [2] TAS1R2,
TAS1R3 💬		[2] Carbohydrate digestion and absorption, Taste transduction 💬[5] 6, 13, 67, 86, 230
114 Arginine glutamate -[0] ---
115 Aluminum hydroxide [1] Aluminum hydroxide[2] Aluminium hydroxide; Aluminum hydroxide; --[2] 11, 46
116 Aminobenzoic acid -[0] ---
117 Acetrizoic acid -[0] ---
118 Amodiaquine hydrochloride -[0] ---
119 Artemisinin -[0] ---
120 Artesunate [1] Artesunate[1] Artesunate; --[8] 18, 46, 53, 66, 96, 97, 215, 271
121 Artemether -[0] ---
122 Aldesulfone sodium -[0] ---
123 Amikacin [1] Amikacin[5] Amikacin; AMIKACIN SULFATE; Amikacina; Amikacine; Arikayce; --[2] 60, 299
124 Atomoxetine hydrochloride [1] Atomoxetine[2] Atomoxetine; Strattera; [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
125 Agomelatine [1] Agomelatine[1] Agomelatine; [3] HTR2C,
MTNR1A,
MTNR1B 💬		[6] Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 6
126 Adalimumab [1] Adalimumab[6] Adalimumab; AMGEVITA; Hulio; Humira; Hyrimoz; Imraldi; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
127 Azaperone -[0] ---
128 Alprostadil alfadex [1] Alprostadil[1] Alprostadil; [1] PTGER1 💬[4] Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬[2] 51, 70
129 Alcloxa -[0] ---
130 Abarelix -[0] ---
131 Acadesine -[0] ---
132 Aceclidine -[0] ---
133 Acitretin [1] Acitretin[1] Acitretin; [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 37
134 Aclarubicin -[0] ---
135 Acrivastine -[0] ---
136 Adefovir [1] Adefovir[1] Adefovir; --[1] 46
137 Adenosine phosphate [1] Adenosine phosphate[0] [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
138 Adinazolam -[0] ---
139 Adinazolam mesylate -[0] ---
140 Adrenalone -[0] ---
141 Abciximab -[0] ---
142 Acacia [1] Acacia[1] Gum Arabic; --[1] 46
143 Acamprosate calcium [1] Acamprosate[1] Acamprosate; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206
144 Agalsidase alfa [1] Agalsidase alfa[5] AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL; [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
145 Alaproclate -[0] ---
146 Albumin aggregated -[0] ---
147 Albumin human [1] Albumin human[5] Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --[3] 2, 78, 96
148 Alcohol diluted [1] Ethanol[3] Alcohol; Ethanol; PREDNISONE; --[7] 13, 51, 58, 97, 279, 280, 298
149 Alefacept [1] Alefacept[1] Alefacept; [1] CD58 💬[2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285
150 Alemtuzumab [1] Alemtuzumab[4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH; [1] CD52 💬-[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
151 Algestone acetophenide -[0] ---
152 Alglucerase [1] Alglucerase[1] Ceredase; [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
153 Alitretinoin [1] Alitretinoin[2] ALITRETINOIN; Toctino; [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
154 Allobarbital -[0] ---
155 Almitrine mesylate -[0] ---
156 Almotriptan -[0] ---
157 Almotriptan malate -[0] ---
158 Alosetron hydrochloride -[0] ---
159 Alovudine -[0] ---
160 Alrestatin sodium -[0] ---
161 Alteplase -[0] ---
162 Altrenogest -[0] ---
163 Altretamine -[0] ---
164 Aluminum acetate -[0] ---
165 Aluminum chloride -[0] ---
166 Aluminum chlorohydrate -[0] ---
167 Aluminum chlorohydrex propylene glycol -[0] ---
168 Aluminum sesquichlorohydrate -[0] ---
169 Aluminum subacetate -[0] ---
170 Aluminum zirconium octachlorohydrex Gly -[0] ---
171 Aluminum zirconium pentachlorohydrate -[0] ---
172 Aluminum zirconium pentachlorohydrex Gly -[0] ---
173 Aluminum zirconium tetrachlorohydrex Gly -[0] ---
174 Aluminum zirconium trichlorohydrex Gly -[0] ---
175 Alverine citrate -[0] ---
176 Alvimopan -[0] ---
177 Alvircept sudotox -[0] ---
178 Ambuphylline -[0] ---
179 Amdinocillin -[0] ---
180 Amdinocillin pivoxil -[0] ---
181 Amdoxovir -[0] ---
182 Amiloxate -[0] ---
183 Aminolevulinic acid hydrochloride [1] Aminolevulinic acid[3] 5-aminolevulinic acid; Aminolevulinic acid; Gliolan; --[5] 34, 96, 97, 254, 286
184 Aminorex -[0] ---
185 Amiodarone [1] Amiodarone[1] AMIODARONE; [16] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[32] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 28, 127
186 Amlintide -[0] ---
187 Amlodipine maleate [1] Amlodipine[1] Amlodipine; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
188 Ammonia solution, strong [1] Ammonia[1] Ammonia; --[3] 86, 88, 296
189 Ammonium carbonate -[0] ---
190 Ammonium lactate -[0] ---
191 Amodiaquine -[0] ---
192 Amorolfine -[0] ---
193 Amoxicillin sodium [1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
194 Amphecloral -[0] ---
195 Amphomycin -[0] ---
196 Amprolium -[0] ---
197 Anagrelide hydrochloride -[0] ---
198 Anakinra [1] Anakinra[2] ANAKINRA; Kineret; [2] IL1R1,
IL1R2 💬		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[19] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
199 Ancestim -[0] ---
200 Ancrod -[0] ---
201 Angiotensin amide -[0] ---
202 Anileridine -[0] ---
203 Anileridine hydrochloride -[0] ---
204 Anise oil -[0] ---
205 Anistreplase -[0] ---
206 Antihemophilic factor [1] Antihemophilic factor, human recombinant[4] ADVATE; Factor VIII; OCTOCOG ALFA; RAHF; --[1] 288
207 Antimony potassium tartrate -[0] ---
208 Apaziquone -[0] ---
209 Apazone -[0] ---
210 Apolizumab -[0] ---
211 Aprepitant -[0] ---
212 Aprindine -[0] ---
213 Aprotinin [1] Aprotinin[1] Aprotinin; --[1] 28
214 Arbutamine hydrochloride -[0] ---
215 Arcitumomab -[0] ---
216 Arginine [1] Arginine[6] Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --[12] 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
217 Arsanilic acid -[0] ---
218 Asoprisnil -[0] ---
219 Asparaginase [1] Asparaginase Escherichia coli[2] Asparaginase; L-asparaginase; --[1] 65
220 Atipamezole -[0] ---
221 Atosiban [1] Atosiban[1] Atosiban; [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 118
222 Atreleuton -[0] ---
223 Atropine oxide hydrochloride [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
224 Avasimibe -[0] ---
225 Avilamycin -[0] ---
226 Avobenzone -[0] ---
227 Azacitidine -[0] ---
228 Azanidazole -[0] ---
229 Azathioprine sodium [1] Azathioprine[3] AZATHIOPRINE; Azatioprina; Imuran; --[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
230 Azelaic acid -[0] ---
231 Azlocillin sodium -[0] ---
232 Abatacept [1] Abatacept[2] Abatacept; ORENCIA; [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
233 Alglucosidase alfa [1] Alglucosidase alfa[4] ALGLUCOSIDASE ALFA; Alpha-glucosidase; Lumizyme; Myozyme; [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256
234 Aliskiren [1] Aliskiren[1] Aliskiren; [1] REN 💬[3] Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[3] 66, 167, 222
235 Anidulafungin -[0] ---
236 Apadenoson -[0] ---
237 Apixaban [1] Apixaban[2] Apixaban; Eliquis; [1] F10 💬[1] Complement and coagulation cascades 💬[3] 96, 97, 222
238 Armodafinil [1] Armodafinil[2] Armodafinil; Modafinil; [1] SLC6A3 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84
239 Avanafil -[0] ---
240 Axitinib [1] Axitinib[1] Axitinib; [3] FLT1,
FLT4,
KDR 💬		[15] Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 34
241 Axomadol -[0] ---
242 Agalsidase beta [1] Agalsidase beta[2] AGALSIDASE BETA; FABRAZYME; [1] GLA 💬[6] Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬[1] 19
243 Atropine methylbromide [1] Atropine[2] Atropina; Atropine; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 2, 299
244 Allylisopropylacetylurea -[0] ---
245 Aminophylline hydrate [1] Aminophylline[1] Aminophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 63
246 Arundic acid [1] Arundic acid[1] Arundic Acid; --[1] 2
247 Azithromycin [1] Azithromycin[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX; --[6] 13, 84, 85, 96, 228, 299
248 Afimoxifene -[0] ---
249 Alcaftadine -[0] ---
250 Aztreonam lysine [1] Aztreonam[2] Aztreonam; Cayston; --[2] 228, 299
251 Antithrombin III human -[0] ---
252 Angelica dahurica root -[0] ---
253 Acetyldigitoxin -[0] ---
254 Aminohippuric acid [1] Aminohippuric acid[1] Aminohippurate; --[4] 49, 53, 67, 86
255 Abacavir [1] Abacavir[4] Abacavir; Abacavir sulfate; Triumeq; Ziagen; --[4] 2, 135, 265, 325
256 Acamprosate [1] Acamprosate[1] Acamprosate; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206
257 Aceglutamide -[0] ---
258 Acenocoumarol -[0] ---
259 Acepromazine -[0] ---
260 Ambrisentan [1] Ambrisentan[3] Ambrisentan; Letairis; Volibris; [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 51, 84, 85, 86, 88, 210, 211
261 Alizapride -[0] ---
262 Albendazole oxide -[0] ---
263 Acetarsol -[0] ---
264 Alclometasone -[0] ---
265 Alendronic acid [1] Alendronic acid[3] Alendronate; Alendronate sodium; ALENDRONIC ACID; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
266 Alfentanil -[0] ---
267 Alfuzosin [1] Alfuzosin[1] Alfuzosin; [1] ADRA1A 💬[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13
268 Alimemazine -[0] ---
269 Almitrine -[0] ---
270 Ademetionine [1] Ademetionine[2] SAM-e; SAMe; --[2] 6, 93
271 Alosetron -[0] ---
272 Alprenolol -[0] ---
273 Azapetine -[0] ---
274 Acipimox [1] Acipimox[1] Acipimox; --[2] 78, 265
275 Azidocillin -[0] ---
276 Alfaxalone -[0] ---
277 Amisulpride -[0] ---
278 Amineptine -[0] ---
279 Adrafinil -[0] ---
280 Acetylleucine -[0] ---
281 Arsthinol -[0] ---
282 Artemotil -[0] ---
283 Artenimol [1] Artenimol[1] Dihydroartemisinin; --[1] 49
284 Ambazone -[0] ---
285 Azidamfenicol -[0] ---
286 Alsactide -[0] ---
287 Almasilate -[0] ---
288 Aloxiprin -[0] ---
289 Afelimomab -[0] ---
290 Alverine -[0] ---
291 Amantadine [1] Amantadine[3] AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI; [5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127
292 Ambroxol [1] Ambroxol[1] Ambroxol; --[2] 6, 19
293 Amfenac -[0] ---
294 Amfepramone -[0] ---
295 Amfetamine -[0] ---
296 Amiloride [1] Amiloride[3] Amiloride; Amiloride Hydrochloride; Midamor; [3] SCNN1A,
SCNN1B,
SCNN1G 💬		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299
297 Amitriptyline [1] Amitriptyline[3] Amitriptylin; AMITRIPTYLINE; Amitriptyline hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299
298 Amitriptylinoxide -[0] ---
299 Amlodipine [1] Amlodipine[1] AMLODIPINE; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
300 Amoxicillin [1] Amoxicillin[4] Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --[9] 6, 19, 46, 63, 84, 96, 97, 222, 299
301 Amtolmetin guacil -[0] ---
302 Amylocaine -[0] ---
303 Anagrelide -[0] ---
304 Androstanolone -[0] ---
305 Anisindione -[0] ---
306 Antazoline -[0] ---
307 Apomorphine [1] Apomorphine[3] APOKYN; Apomorfina; Apomorphine; [2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
308 Apraclonidine [1] Apraclonidine[1] Apraclonidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11
309 Arbekacin -[0] ---
310 Arformoterol -[0] ---
311 Arotinolol -[0] ---
312 Articaine -[0] ---
313 Aspoxicillin -[0] ---
314 Atazanavir [1] Atazanavir[2] Atazanavir; Reyataz; --[1] 265
315 Atomoxetine [1] Atomoxetine[2] Atomoxetine; Strattera; [1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
316 Atorvastatin [1] Atorvastatin[3] Atorvastatin; Atorvastatin calcium; Lipitor; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
317 Aurotioprol -[0] ---
318 Azapentacene -[0] ---
319 Azatadine -[0] ---
320 Azelastine -[0] ---
321 Azintamide -[0] ---
322 Azithromycin [1] Azithromycin[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX; --[6] 13, 84, 85, 96, 228, 299
323 Adomiparin [3] Enoxaparin,
Heparin,
Parnaparin		[5] Enoxaparin; Heparin; Heparin Sodium; Parnaparin; PARNAPARIN SODIUM; [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[14] 46, 47, 60, 70, 79, 84, 97, 107, 224, 226, 280, 299, 316, 317
324 Acetyldigoxin -[0] ---
325 Alatrofloxacin -[0] ---
326 Aminolevulinic acid [1] Aminolevulinic acid[3] 5-aminolevulinic acid; Aminolevulinic acid; Gliolan; --[5] 34, 96, 97, 254, 286
327 Aminomethylbenzoic acid -[0] ---
328 Amprolium hydrochloride -[0] ---
329 Arginine aspartate -[0] ---
330 Ascorbic acid calcium salt -[0] ---
331 Asiaticoside -[0] ---
332 Attapulgite -[0] ---
333 Aescine -[0] ---
334 Azilsartan medoxomil -[0] ---
335 Aleplasinin -[0] ---
336 Apricoxib -[0] ---
337 Adipiplon -[0] ---
338 Agatolimod -[0] ---
339 Albiglutide -[0] ---
340 Albinterferon alfa-2b -[0] ---
341 Aleglitazar -[0] ---
342 Alferminogene tadenovec -[0] ---
343 Alfimeprase -[0] ---
344 Aluminum sulfate -[0] ---
345 Amibegron -[0] ---
346 Amrubicin -[0] ---
347 Anacetrapib [1] Anacetrapib[1] ANACETRAPIB; [1] CETP 💬[1] Cholesterol metabolism 💬[1] 79
348 Anrukinzumab [1] Anrukinzumab[1] Anrukinzumab; [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[1] 97
349 Antithrombin alfa -[0] ---
350 Apratastat [1] Apratastat[1] Apratastat; [2] ADAM17,
MMP13 💬		[7] Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬[1] 46
351 Apremilast [1] Apremilast[2] APREMILAST; Otezla; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
352 Arbaclofen placarbil [1] Arbaclofen Placarbil[1] Arbaclofen Placarbil; [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 13
353 Ataluren [1] Ataluren[2] ATALUREN; Translarna; --[6] 19, 113, 140, 246, 299, 329
354 Aflibercept [1] Aflibercept[2] Aflibercept; Eylea; [3] PGF,
VEGFA,
VEGFB 💬		[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 90, 166
355 Afegostat [1] Afegostat[1] Afegostat; --[1] 19
356 Arhalofenate -[0] ---
357 Astuprotimut-R -[0] ---
358 Atagabalin -[0] ---
359 Albaconazole -[0] ---
360 Atacicept [1] Atacicept[2] ATACICEPT; TACI-Fc5; [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66
361 Afatinib -[0] ---
362 Asparagine -[0] ---
363 Amatuximab -[0] ---
364 Anagliptin -[0] ---
365 Arbaclofen [1] Arbaclofen[2] Arbaclofen; Baclofen; [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[2] 13, 206
366 Aganepag isopropyl -[0] ---
367 Amuvatinib -[0] ---
368 Atopaxar -[0] ---
369 Alvocidib -[0] ---
370 Avagacestat -[0] ---
371 Almorexant -[0] ---
372 Azficel-T -[0] ---
373 Anivamersen -[0] ---
374 Abexinostat -[0] ---
375 Alisertib -[0] ---
376 Alisporivir -[0] ---
377 Amitifadine -[0] ---
378 Amonafide -[0] ---
379 Asunaprevir -[0] ---
380 Abediterol -[0] ---
381 Amifampridine [1] Amifampridine[2] Amifampridine; Firdapse; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12
382 Avatrombopag [1] Avatrombopag[2] Avatrombopag; Doptelet; [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[2] 60, 63
383 Alirocumab [1] Alirocumab[2] ALIROCUMAB; Praluent; [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
384 Actoxumab -[0] ---
385 Afoxolaner -[0] ---
386 Aripiprazole lauroxil -[0] ---
387 Afuresertib -[0] ---
388 Aldoxorubicin -[0] ---
389 Afamelanotide [1] Afamelanotide[2] AFAMELANOTIDE; SCENESSE; [1] MC1R 💬[2] Melanogenesis, Neuroactive ligand-receptor interaction 💬[3] 159, 161, 254
390 Aldosterone [1] Aldosterone[1] Aldosterone; [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[1] 222
391 Abrilumab [1] Abrilumab[1] Abrilumab; [2] ITGA4,
ITGB7 💬		[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[2] 96, 97
392 Aducanumab -[0] ---
393 Alectinib -[0] ---
394 Apitolisib -[0] ---
395 Amenamevir -[0] ---
396 Asfotase alfa [1] Asfotase alfa[2] ASFOTASE ALFA; Strensiq; [1] ALPL 💬[4] Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬[1] 172
397 Antithrombin gamma -[0] ---
398 Abametapir -[0] ---
399 Abemaciclib [1] Abemaciclib[1] Abemaciclib; [2] CDK4,
CDK6 💬		[29] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Breast cancer, Cell cycle, Cellular senescence, Chronic myeloid leukemia, Cushing syndrome, Endocrine resistance, Epstein-Barr virus infection, Glioma, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Measles, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Viral carcinogenesis, p53 signaling pathway 💬[1] 34
400 Axelopran -[0] ---
401 Albutrepenonacog alfa -[0] ---
402 Atezolizumab [1] Atezolizumab[1] Atezolizumab; [1] CD274 💬[2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85
403 Avelumab -[0] ---
404 Alipogene tiparvovec -[0] ---
405 Adomeglivant -[0] ---
406 Abaloparatide -[0] ---
407 Acalabrutinib [1] Acalabrutinib[1] Acalabrutinib; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 61
408 Afasevikumab -[0] ---
409 Amcasertib -[0] ---
410 Alpelisib -[0] ---
411 Aceneuramic acid [1] Aceneuramic acid[1] ACENEURAMIC ACID; --[1] 30
412 Andexanet alfa -[0] ---
413 Apalutamide -[0] ---
414 Anifrolumab [1] Anifrolumab[1] ANIFROLUMAB; [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[2] 46, 49
415 Avacopan [1] Avacopan[1] Avacopan; [1] C5AR1 💬[6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬[3] 43, 44, 222
416 Apabetalone [1] Apabetalone[1] Apabetalone; [4] BRD2,
BRD3,
BRD4,
BRDT 💬		-[1] 86
417 Avadomide -[0] ---
418 Axicabtagene ciloleucel -[0] ---
419 Azeliragon -[0] ---
420 Adagloxad simolenin -[0] ---
421 Avapritinib -[0] ---
422 Abivertinib -[0] ---
423 Atogepant -[0] ---
424 Adafosbuvir -[0] ---
425 Arimoclomol [1] Arimoclomol[1] ARIMOCLOMOL; --[3] 2, 15, 19
426 Abrocitinib -[0] ---
427 Asciminib -[0] ---
428 Avexitide -[0] ---
429 Aprocitentan -[0] ---
430 Atabecestat -[0] ---
431 Atoltivimab -[0] ---
432 Abicipar pegol -[0] ---
433 Amylopectin -[0] ---
434 Ampreloxetine [1] Ampreloxetine[1] Ampreloxetine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 17
435 Ascrinvacumab -[0] ---
436 Aldafermin -[0] ---
437 Avalglucosidase alfa [1] Avalglucosidase alfa[2] Avalglucosidase Alfa; NeoGAA; [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256
438 Asenapine -[0] ---
439 Apitegromab [1] Apitegromab[1] Apitegromab; [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 3
440 Adriforant -[0] ---
441 Astegolimab -[0] ---
442 Ansuvimab -[0] ---
443 Amivantamab -[0] ---
444 Afimetoran [1] Afimetoran[1] BMS-986256; --[1] 49
445 Axatilimab -[0] ---
446 Aviptadil [1] Aviptadil[1] Aviptadil; --[5] 49, 51, 84, 85, 86