Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	TPH2	[4] Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse	D09973	Telotristat	[1] 97
2	DHFR	[3] One carbon pool by folate, Folate biosynthesis, Metabolic pathways	D00142	Methotrexate	[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
3	DHFR	[3] One carbon pool by folate, Folate biosynthesis, Metabolic pathways	D02115	Methotrexate	[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
4	DHFR2	[3] One carbon pool by folate, Folate biosynthesis, Metabolic pathways	D00142	Methotrexate	[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
5	DHFR2	[3] One carbon pool by folate, Folate biosynthesis, Metabolic pathways	D02115	Methotrexate	[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
6	ALPL	[3] Thiamine metabolism, Folate biosynthesis, Metabolic pathways	D10595	Asfotase alfa	[1] 172
7	PAH	[4] Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthesis, Metabolic pathways	D11077	Pegvaliase	[1] 240
8	TPH1	[4] Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse	D09973	Telotristat	[1] 97