Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Herpes simplex virus 1 infection 💬
 [1] BCL2 💬 D10679 💬 Venetoclax [1] 28 💬
2 Herpes simplex virus 1 infection 💬
 [1] C3 💬 D11613 💬 Pegcetacoplan [3]  2 , 62, 222 💬
3 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D11696 💬 Crovalimab [2] 62, 109 💬
4 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D03940 💬 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222 💬
5 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D11473 💬 Nomacopan [3] 62, 109, 162 💬
6 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D11477 💬 Pozelimab [2] 11, 62 💬
7 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D11054 💬 Ravulizumab [7]  2 , 11, 13, 50, 62, 66, 109 💬
8 Herpes simplex virus 1 infection 💬
 [1] C5 💬 D11838 💬 Vilobelimab [3] 43, 44, 269 💬
9 Herpes simplex virus 1 infection 💬
 [1] CASP9 💬 D11195 💬 Rimiducid [6] 19, 60, 65, 284, 285, 326 💬
10 Herpes simplex virus 1 infection 💬
 [4] CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
11 Herpes simplex virus 1 infection 💬
 [1] CD74 💬 D08944 💬 Milatuzumab [1] 49 💬
12 Herpes simplex virus 1 infection 💬
 [20] HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 D04318 💬 Glatiramer [4]  2 , 13, 96, 156 💬
13 Herpes simplex virus 1 infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab [1] 49 💬
14 Herpes simplex virus 1 infection 💬
 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab [1] 49 💬
15 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D11082 💬 Anifrolumab [2] 46, 49 💬
16 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D03305 💬 Interferon alfa [6] 13, 25, 26, 28, 56, 96 💬
17 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D00745 💬 Interferon alfa-2a [1] 56 💬
18 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D02745 💬 Interferon alfa-2b [2] 25, 34 💬
19 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D04554 💬 Interferon beta-1a [4] 13, 26, 96, 97 💬
20 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D00746 💬 Interferon beta-1b [1] 13 💬
21 Herpes simplex virus 1 infection 💬
 [2] IFNAR1, IFNAR2 💬 D10483 💬 Peginterferon beta-1a [1] 13 💬
22 Herpes simplex virus 1 infection 💬
 [1] IFNG 💬 D11120 💬 Emapalumab [2] 49, 107 💬
23 Herpes simplex virus 1 infection 💬
 [1] IFNG 💬 D04242 💬 Fontolizumab [1] 46 💬
24 Herpes simplex virus 1 infection 💬
 [2] IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
25 Herpes simplex virus 1 infection 💬
 [2] IL12A, IL12B 💬 D09214 💬 Ustekinumab [17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
26 Herpes simplex virus 1 infection 💬
 [1] IL1B 💬 D09315 💬 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
27 Herpes simplex virus 1 infection 💬
 [1] IL1B 💬 D09911 💬 Gevokizumab [4] 41, 50, 56, 269 💬
28 Herpes simplex virus 1 infection 💬
 [1] IL1B 💬 D06635 💬 Rilonacept [4] 51, 106, 107, 266 💬
29 Herpes simplex virus 1 infection 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
30 Herpes simplex virus 1 infection 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
31 Herpes simplex virus 1 infection 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
32 Herpes simplex virus 1 infection 💬
 [1] JAK1 💬 D10871 💬 Filgotinib [6] 46, 53, 96, 97, 222, 271 💬
33 Herpes simplex virus 1 infection 💬
 [1] JAK1 💬 D10944 💬 Itacitinib [5] 46, 51, 60, 97, 228 💬
34 Herpes simplex virus 1 infection 💬
 [1] JAK1 💬 D10994 💬 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271 💬
35 Herpes simplex virus 1 infection 💬
 [2] JAK1, JAK2 💬 D10308 💬 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
36 Herpes simplex virus 1 infection 💬
 [2] JAK1, JAK2 💬 D10653 💬 Peficitinib [1] 46 💬
37 Herpes simplex virus 1 infection 💬
 [2] JAK1, JAK2 💬 D09959 💬 Ruxolitinib [1] 228 💬
38 Herpes simplex virus 1 infection 💬
 [3] JAK1, JAK2, TYK2 💬 D09970 💬 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
39 Herpes simplex virus 1 infection 💬
 [1] LTA 💬 D10187 💬 Pateclizumab [1] 46 💬
40 Herpes simplex virus 1 infection 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
41 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
42 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [41]  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
43 Herpes simplex virus 1 infection 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [4] 13, 34, 89, 331 💬
44 Herpes simplex virus 1 infection 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
45 Herpes simplex virus 1 infection 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
46 Herpes simplex virus 1 infection 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
47 Herpes simplex virus 1 infection 💬
 [1] PML 💬 D00094 💬 Tretinoin [6]  2 , 62, 63, 75, 94, 231 💬
48 Herpes simplex virus 1 infection 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
49 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
50 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
51 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
52 Herpes simplex virus 1 infection 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
53 Herpes simplex virus 1 infection 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
54 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
55 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
56 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
57 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
58 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
59 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
60 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
61 Herpes simplex virus 1 infection 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
62 Herpes simplex virus 1 infection 💬
 [1] TYK2 💬 D11817 💬 Deucravacitinib [2] 96, 97 💬