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No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
FCER1A
💬
1. FCER1A
×
Name
Full Name
FCER1A
Fc fragment of IgE receptor Ia
4件:
Sphingolipid signaling pathway
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Fc epsilon RI signaling pathway
,
Asthma
4件:
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Fc epsilon RI signaling pathw
...
Omalizumab
Omalizumab
💬
1. FCER1A
×
Name
Other Names
Omalizumab
Omalizumab (USAN/INN)
Omalizumab (genetical recombination) (JAN)
Xolair (TN)
オマリズマブ
ゾレア
Omalizumab
7件:
46
46
,
53
,
65
,
98
,
162
,
226
,
299
💬
1. FCER1A
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
53
シェーグレン症候群
Sjogren syndrome
65
原発性免疫不全症候群
Primary immunodeficiency
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
162
類天疱瘡(後天性表皮水疱症を含む。)
Pemphigoid
226
間質性膀胱炎(ハンナ型)
Interstitial cystitis with Hunners ulcer
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
2
IL4
💬
2. IL4
×
Name
Full Name
IL4
interleukin 4
16件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Leishmaniasis
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
16件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
Binetrakin
Binetrakin
💬
2. IL4
×
Name
Other Names
Binetrakin
Binetrakin (USAN/INN)
ビネトラキン
Binetrakin
1件:
46
46
💬
2. IL4
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
3
IL5
💬
3. IL5
×
Name
Full Name
IL5
interleukin 5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Mepolizumab
Mepolizumab
💬
3. IL5
×
Name
Other Names
Mepolizumab
Mepolizumab (USAN/INN)
Mepolizumab (genetical recombination) (JAN)
Nucala (TN)
メポリズマブ
ヌーカラ
Mepolizumab
4件:
44
44
,
45
,
98
,
162
💬
3. IL5
×
告示番号
日本語名
英語名
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
45
好酸球性多発血管炎性肉芽腫症;アレルギー性肉芽腫性血管炎;チャーグ・ストラウス症候群
Eosinophilic granulomatosis with Polyangiitis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
162
類天疱瘡(後天性表皮水疱症を含む。)
Pemphigoid
4
IL5
💬
4. IL5
×
Name
Full Name
IL5
interleukin 5
13件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Intestinal immune network for IgA production
,
Pathways in cancer
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Allograft rejection
13件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
, ...
Reslizumab
Reslizumab
💬
4. IL5
×
Name
Other Names
Reslizumab
Reslizumab (USAN)
Cinqaero (TN)
Cinqair (TN)
レスリズマブ
Reslizumab
2件:
44
44
,
98
💬
4. IL5
×
告示番号
日本語名
英語名
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
98
好酸球性消化管疾患
Eosinophilic gastrointestinal disease
5
IL10
💬
5. IL10
×
Name
Full Name
IL10
interleukin 10
22件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
FoxO signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
T cell receptor signaling pathway
,
Intestinal immune network for IgA production
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Staphylococcus aureus infection
,
Tuberculosis
,
Asthma
,
Autoimmune thyroid disease
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Allograft rejection
22件:
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine re
...
Pirfenidone
Pirfenidone
💬
5. IL10
×
Name
Other Names
Pirfenidone
Pirfenidone (JAN/USAN/INN)
Esbriet (TN)
ピルフェニドン
ピレスパ
Pirfenidone
11件:
13
13
,
34
,
46
,
50
,
51
,
58
,
84
,
85
,
164
,
222
,
228
💬
5. IL10
×
告示番号
日本語名
英語名
13
多発性硬化症/視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
34
神経線維腫症
Neurofibromatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
58
肥大型心筋症
Hypertrophic cardiomyopathy
84
サルコイドーシス
Sarcoidosis
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
164
眼皮膚白皮症
Oculocutaneous albinism
222
一次性ネフローゼ症候群
Primary nephrotic syndrome
228
閉塞性細気管支炎
Bronchiolitis obliterans
6
IL13
💬
6. IL13
×
Name
Full Name
IL13
interleukin 13
8件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Fc epsilon RI signaling pathway
,
Pathways in cancer
,
Asthma
,
Inflammatory bowel disease
8件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1
...
Anrukinzumab
Anrukinzumab
💬
6. IL13
×
Name
Other Names
Anrukinzumab
Anrukinzumab (USAN)
アンルキンズマブ
Anrukinzumab
1件:
97
97
💬
6. IL13
×
告示番号
日本語名
英語名
97
潰瘍性大腸炎
Ulcerative colitis
7
IL13
💬
7. IL13
×
Name
Full Name
IL13
interleukin 13
8件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Fc epsilon RI signaling pathway
,
Pathways in cancer
,
Asthma
,
Inflammatory bowel disease
8件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1
...
Lebrikizumab
Lebrikizumab
💬
7. IL13
×
Name
Other Names
Lebrikizumab
Lebrikizumab (USAN/INN)
Lebrikizumab (genetical recombination) (JAN)
レブリキズマブ
Lebrikizumab
1件:
85
85
💬
7. IL13
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
8
IL13
💬
8. IL13
×
Name
Full Name
IL13
interleukin 13
8件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Fc epsilon RI signaling pathway
,
Pathways in cancer
,
Asthma
,
Inflammatory bowel disease
8件:
Cytokine-cytokine receptor interaction
,
JAK-STAT signaling pathway
,
IL-17 signaling pathway
,
Th1
...
Tralokinumab
Tralokinumab
💬
8. IL13
×
Name
Other Names
Tralokinumab
Tralokinumab (USAN/INN)
Tralokinumab (genetical recombination) (JAN)
Tralokinumab-ldrm
Adbry (TN)
Adtralza (TN)
トラロキヌマブ
アドトラーザ
Tralokinumab
2件:
85
85
,
97
💬
8. IL13
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
97
潰瘍性大腸炎
Ulcerative colitis
9
TNF
💬
9. TNF
×
Name
Full Name
TNF
tumor necrosis factor
67件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Apoptosis
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Asthma
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Dilated cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
67件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral pr
...
Etanercept
Etanercept
💬
9. TNF
×
Name
Other Names
Etanercept
Etanercept (USAN/INN)
Etanercept (genetical recombination) (JAN)
Etanercept (genetical recombination) [Etanercept biosimilar 1] (JAN)
Etanercept (genetical recombination) [Etanercept biosimilar 2] (JAN)
Enbrel (TN)
エタネルセプト
エンブレル
エタネルセプトBS
Etanercept
16件:
15
15
,
28
,
35
,
38
,
39
,
46
,
50
,
53
,
56
,
60
,
85
,
107
,
228
,
270
,
271
,
285
💬
9. TNF
×
告示番号
日本語名
英語名
15
封入体筋炎
Inclusion body myositis
28
全身性アミロイドーシス
Systemic amyloidosis
35
天疱瘡
Pemphigus
38
スティーヴンス・ジョンソン症候群;皮膚粘膜眼症候群
Stevens-Johnson syndrome
39
中毒性表皮壊死症
Toxic epidermal necrolysis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
50
皮膚筋炎/多発性筋炎
Dermatomyositis
53
シェーグレン症候群
Sjogren syndrome
56
ベーチェット病
Behcet disease
60
再生不良性貧血
Aplastic anemia
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
107
若年性特発性関節炎
Juvenile idiopathic arthritis
228
閉塞性細気管支炎
Bronchiolitis obliterans
270
慢性再発性多発性骨髄炎
Chronic recurrent multifocal osteomyelitis
271
強直性脊椎炎
Ankylosing spondylitis
285
ファンコニ貧血
Fanconi anemia
10
TNF
💬
10. TNF
×
Name
Full Name
TNF
tumor necrosis factor
67件:
Antifolate resistance
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
NF-kappa B signaling pathway
,
Sphingolipid signaling pathway
,
mTOR signaling pathway
,
Apoptosis
,
Necroptosis
,
TGF-beta signaling pathway
,
Osteoclast differentiation
,
Antigen processing and presentation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Hematopoietic cell lineage
,
Natural killer cell mediated cytotoxicity
,
IL-17 signaling pathway
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Adipocytokine signaling pathway
,
Type II diabetes mellitus
,
Insulin resistance
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Alzheimer disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Legionellosis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Asthma
,
Inflammatory bowel disease
,
Systemic lupus erythematosus
,
Rheumatoid arthritis
,
Allograft rejection
,
Graft-versus-host disease
,
Hypertrophic cardiomyopathy
,
Dilated cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
67件:
Antifolate resistance
,
MAPK signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral pr
...
Thalidomide
Thalidomide
💬
10. TNF
×
Name
Other Names
Thalidomide
Thalidomide (JAN/USP/INN)
Thalomid (TN)
Thaled (TN)
サリドマイド
サレド
Thalidomide
20件:
2
2
,
16
,
20
,
28
,
49
,
51
,
53
,
56
,
65
,
84
,
85
,
94
,
96
,
97
,
227
,
271
,
280
,
298
,
300
,
331
💬
10. TNF
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
16
クロウ・深瀬症候群
Crow-Fukase syndrome
20
副腎白質ジストロフィー
Adrenoleukodystrophy
28
全身性アミロイドーシス
Systemic amyloidosis
49
全身性エリテマトーデス
Systemic lupus erythematosus
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
56
ベーチェット病
Behcet disease
65
原発性免疫不全症候群
Primary immunodeficiency
84
サルコイドーシス
Sarcoidosis
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
94
原発性硬化性胆管炎
Primary sclerosing cholangitis
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
227
オスラー病;遺伝性出血性末梢血管拡張症
Osler disease
271
強直性脊椎炎
Ankylosing spondylitis
280
巨大動静脈奇形(頚部顔面又は四肢病変)
Huge arteriovenous malformation with cervicofacial or limb lesion
298
遺伝性膵炎
Hereditary pancreatitis
300
IgG4関連疾患
IgG4-related disease
331
特発性多中心性キャッスルマン病
Idiopathic multicentric castleman disease