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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
28件:
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
28件:
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
1. CDK4
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
23件:
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
23件:
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
2. CDK6
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
3
BCL2
💬
3. BCL2
×
Name
Full Name
BCL2
BCL2 apoptosis regulator
43件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
Platinum drug resistance
,
NF-kappa B signaling pathway
,
HIF-1 signaling pathway
,
Sphingolipid signaling pathway
,
p53 signaling pathway
,
Autophagy - animal
,
Protein processing in endoplasmic reticulum
,
PI3K-Akt signaling pathway
,
Apoptosis
,
Apoptosis - multiple species
,
Necroptosis
,
Adrenergic signaling in cardiomyocytes
,
Hedgehog signaling pathway
,
Focal adhesion
,
NOD-like receptor signaling pathway
,
JAK-STAT signaling pathway
,
Neurotrophin signaling pathway
,
Cholinergic synapse
,
Estrogen signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
AGE-RAGE signaling pathway in diabetic complications
,
Amyotrophic lateral sclerosis
,
Pathways of neurodegeneration - multiple diseases
,
Shigellosis
,
Salmonella infection
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Measles
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - receptor activation
,
Colorectal cancer
,
Prostate cancer
,
Small cell lung cancer
,
Gastric cancer
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
43件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
Platinum drug resistance
,
NF-k
...
Venetoclax
Venetoclax
💬
3. BCL2
×
Name
Other Names
Venetoclax
Venetoclax (JAN/USAN/INN)
Venclexta (TN)
ベネトクラクス
ベネクレクスタ
Venetoclax
1件:
28
28
💬
3. BCL2
×
告示番号
日本語名
英語名
28
全身性アミロイドーシス
Systemic amyloidosis
4
RRM2
💬
4. RRM2
×
Name
Full Name
RRM2
ribonucleotide reductase regulatory subunit M2
7件:
Purine metabolism
Purine metabolism
,
Pyrimidine metabolism
,
Glutathione metabolism
,
Drug metabolism - other enzymes
,
Metabolic pathways
,
Nucleotide metabolism
,
p53 signaling pathway
7件:
Purine metabolism
,
Pyrimidine metabolism
,
Glutathione metabolism
,
Drug metabolism - other enzyme
...
Hydroxyurea
Hydroxyurea
💬
4. RRM2
×
Name
Other Names
Hydroxyurea
Hydroxyurea (USP)
Hydroxycarbamide (JAN/INN)
Droxia (TN)
Hydrea (TN)
Siklos (TN)
ヒドロキシカルバミド
ハイドレア
Hydroxyurea
8件:
3
3
,
13
,
19
,
20
,
65
,
85
,
86
,
284
💬
4. RRM2
×
告示番号
日本語名
英語名
3
脊髄性筋萎縮症
Spinal muscular atrophy
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
19
ライソゾーム病
Lysosomal storage disease
20
副腎白質ジストロフィー
Adrenoleukodystrophy
65
原発性免疫不全症候群
Primary immunodeficiency
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
284
ダイアモンド・ブラックファン貧血
Diamond-Blackfan anemia
5
CASP9
💬
5. CASP9
×
Name
Full Name
CASP9
caspase 9
35件:
Platinum drug resistance
Platinum drug resistance
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Apoptosis
,
Apoptosis - multiple species
,
VEGF signaling pathway
,
Thyroid hormone signaling pathway
,
Alzheimer disease
,
Parkinson disease
,
Amyotrophic lateral sclerosis
,
Huntington disease
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Pathogenic Escherichia coli infection
,
Legionellosis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Pathways in cancer
,
Colorectal cancer
,
Pancreatic cancer
,
Endometrial cancer
,
Prostate cancer
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Viral myocarditis
,
Lipid and atherosclerosis
35件:
Platinum drug resistance
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Apoptosis
,
Apoptos
...
Rimiducid
Rimiducid
💬
5. CASP9
×
Name
Other Names
Rimiducid
Rimiducid (USAN/INN)
リミドゥシド
Rimiducid
6件:
19
19
,
60
,
65
,
284
,
285
,
326
💬
5. CASP9
×
告示番号
日本語名
英語名
19
ライソゾーム病
Lysosomal storage disease
60
再生不良性貧血
Aplastic anemia
65
原発性免疫不全症候群
Primary immunodeficiency
284
ダイアモンド・ブラックファン貧血
Diamond-Blackfan anemia
285
ファンコニ貧血
Fanconi anemia
326
大理石骨病
Osteopetrosis