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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CDK4
💬
1. CDK4
×
Name
Full Name
CDK4
cyclin dependent kinase 4
28件:
Endocrine resistance
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Tight junction
,
T cell receptor signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Human T-cell leukemia virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Bladder cancer
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
28件:
Endocrine resistance
,
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular s
...
Abemaciclib
Abemaciclib
💬
1. CDK4
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
1. CDK4
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
2
CDK6
💬
2. CDK6
×
Name
Full Name
CDK6
cyclin dependent kinase 6
23件:
Cell cycle
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syndrome
,
Hepatitis C
,
Measles
,
Human cytomegalovirus infection
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Pancreatic cancer
,
Glioma
,
Melanoma
,
Chronic myeloid leukemia
,
Small cell lung cancer
,
Non-small cell lung cancer
,
Breast cancer
,
Hepatocellular carcinoma
23件:
Cell cycle
,
p53 signaling pathway
,
PI3K-Akt signaling pathway
,
Cellular senescence
,
Cushing syn
...
Abemaciclib
Abemaciclib
💬
2. CDK6
×
Name
Other Names
Abemaciclib
Abemaciclib (JAN/USAN)
Verzenio (TN)
アベマシクリブ
ベージニオ
Abemaciclib
1件:
34
34
💬
2. CDK6
×
告示番号
日本語名
英語名
34
神経線維腫症
Neurofibromatosis
3
ABL1
💬
3. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Bosutinib
Bosutinib
💬
3. ABL1
×
Name
Other Names
Bosutinib
Bosutinib (USAN)
ボスチニブ
Bosutinib
2件:
2
2
,
67
💬
3. ABL1
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
67
多発性嚢胞腎
Polycystic kidney disease
4
ABL1
💬
4. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Dasatinib
Dasatinib
💬
4. ABL1
×
Name
Other Names
Dasatinib
Dasatinib (JAN/INN)
ダサチニブ
Dasatinib
2件:
51
51
,
85
💬
4. ABL1
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
5
ABL1
💬
5. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Dasatinib
Dasatinib
💬
5. ABL1
×
Name
Other Names
Dasatinib
Dasatinib (USAN)
Dasatinib hydrate (JAN)
Sprycel (TN)
ダサチニブ水和物
スプリセル
Dasatinib
2件:
51
51
,
85
💬
5. ABL1
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
6
ABL1
💬
6. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Imatinib
Imatinib
💬
6. ABL1
×
Name
Other Names
Imatinib
Imatinib (INN)
Glamox (TN)
イマチニブ
Imatinib
12件:
13
13
,
28
,
34
,
35
,
46
,
51
,
85
,
86
,
87
,
88
,
89
,
162
💬
6. ABL1
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
28
全身性アミロイドーシス
Systemic amyloidosis
34
神経線維腫症
Neurofibromatosis
35
天疱瘡
Pemphigus
46
悪性関節リウマチ
Malignant rheumatoid arthritis
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
87
肺静脈閉塞症／肺毛細血管腫症
Pulmonary veno-occlusive disease
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
89
リンパ脈管筋腫症
Lymphangioleiomyomatosis
162
類天疱瘡（後天性表皮水疱症を含む。）
Pemphigoid
7
ABL1
💬
7. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Nilotinib
Nilotinib
💬
7. ABL1
×
Name
Other Names
Nilotinib
Nilotinib (USAN/INN)
ニロチニブ
Nilotinib
5件:
6
6
,
8
,
34
,
51
,
86
💬
7. ABL1
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
8
ハンチントン病
Huntington disease
34
神経線維腫症
Neurofibromatosis
51
全身性強皮症
Scleroderma
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
8
ABL1
💬
8. ABL1
×
Name
Full Name
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
11件:
ErbB signaling pathway
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signaling pathway
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
MicroRNAs in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chronic myeloid leukemia
,
Viral myocarditis
11件:
ErbB signaling pathway
,
Ras signaling pathway
,
Cell cycle
,
Axon guidance
,
Neurotrophin signalin
...
Saracatinib
Saracatinib
💬
8. ABL1
×
Name
Other Names
Saracatinib
Saracatinib (USAN/INN)
サラカチニブ
Saracatinib
3件:
6
6
,
89
,
272
💬
8. ABL1
×
告示番号
日本語名
英語名
6
パーキンソン病
Parkinson disease
89
リンパ脈管筋腫症
Lymphangioleiomyomatosis
272
進行性骨化性線維異形成症
Fibrodysplasia ossificans progressiva
9
HDAC1
💬
9. HDAC1
×
Name
Full Name
HDAC1
histone deacetylase 1
15件:
Cell cycle
Cell cycle
,
Longevity regulating pathway - multiple species
,
Notch signaling pathway
,
Neutrophil extracellular trap formation
,
Thyroid hormone signaling pathway
,
Huntington disease
,
Amphetamine addiction
,
Alcoholism
,
Human papillomavirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Chronic myeloid leukemia
15件:
Cell cycle
,
Longevity regulating pathway - multiple species
,
Notch signaling pathway
,
Neutrophi
...
Vorinostat
Vorinostat
💬
9. HDAC1
×
Name
Other Names
Vorinostat
Vorinostat (JAN/USAN)
Zolinza (TN)
ボリノスタット
ゾリンザ
Vorinostat
2件:
75
75
,
96
💬
9. HDAC1
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
96
クローン病;回腸末端炎
Crohn disease
10
HDAC2
💬
10. HDAC2
×
Name
Full Name
HDAC2
histone deacetylase 2
15件:
Cell cycle
Cell cycle
,
Longevity regulating pathway - multiple species
,
Notch signaling pathway
,
Neutrophil extracellular trap formation
,
Thyroid hormone signaling pathway
,
Huntington disease
,
Amphetamine addiction
,
Alcoholism
,
Human papillomavirus infection
,
Epstein-Barr virus infection
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Viral carcinogenesis
,
MicroRNAs in cancer
,
Chronic myeloid leukemia
15件:
Cell cycle
,
Longevity regulating pathway - multiple species
,
Notch signaling pathway
,
Neutrophi
...
Vorinostat
Vorinostat
💬
10. HDAC2
×
Name
Other Names
Vorinostat
Vorinostat (JAN/USAN)
Zolinza (TN)
ボリノスタット
ゾリンザ
Vorinostat
2件:
75
75
,
96
💬
10. HDAC2
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
96
クローン病;回腸末端炎
Crohn disease