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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CYP11A1
💬
1. CYP11A1
×
Name
Full Name
CYP11A1
cytochrome P450 family 11 subfamily A member 1
6件:
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
6件:
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Aldosterone synthesis
...
Levoketoconazole
Levoketoconazole
💬
1. CYP11A1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
レボケトコナゾール
Levoketoconazole
1件:
75
75
💬
1. CYP11A1
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
2
CYP17A1
💬
2. CYP17A1
×
Name
Full Name
CYP17A1
cytochrome P450 family 17 subfamily A member 1
6件:
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling pathway
,
Cortisol synthesis and secretion
,
Cushing syndrome
6件:
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling p
...
Ketoconazole
Ketoconazole
💬
2. CYP17A1
×
Name
Other Names
Ketoconazole
Ketoconazole (JP18/USP)
Nizoral (TN)
Xolegel (TN)
ケトコナゾール
略語 KCZ
ニゾラール
Ketoconazole
3件:
8
8
,
13
,
75
💬
2. CYP17A1
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
75
クッシング病
Cushing disease
3
CYP17A1
💬
3. CYP17A1
×
Name
Full Name
CYP17A1
cytochrome P450 family 17 subfamily A member 1
6件:
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling pathway
,
Cortisol synthesis and secretion
,
Cushing syndrome
6件:
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
,
Prolactin signaling p
...
Levoketoconazole
Levoketoconazole
💬
3. CYP17A1
×
Name
Other Names
Levoketoconazole
Levoketoconazole (USAN/INN)
Recorlev (TN)
レボケトコナゾール
Levoketoconazole
1件:
75
75
💬
3. CYP17A1
×
告示番号
日本語名
英語名
75
クッシング病
Cushing disease
4
CYP19A1
💬
4. CYP19A1
×
Name
Full Name
CYP19A1
cytochrome P450 family 19 subfamily A member 1
3件:
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
Anastrozole
Anastrozole
💬
4. CYP19A1
×
Name
Other Names
Anastrozole
Anastrozole (JP18/USP/INN)
Arimidex (TN)
アナストロゾール
アリミデックス
Anastrozole
3件:
78
78
,
86
,
193
💬
4. CYP19A1
×
告示番号
日本語名
英語名
78
下垂体前葉機能低下症
Hypopituitarism
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
193
プラダー・ウィリ症候群
Prader-Willi syndrome
5
CYP19A1
💬
5. CYP19A1
×
Name
Full Name
CYP19A1
cytochrome P450 family 19 subfamily A member 1
3件:
Steroid hormone biosynthesis
Steroid hormone biosynthesis
,
Metabolic pathways
,
Ovarian steroidogenesis
Letrozole
Letrozole
💬
5. CYP19A1
×
Name
Other Names
Letrozole
Letrozole (JAN/USP/INN)
Femara (TN)
レトロゾール
フェマーラ
Letrozole
2件:
81
81
,
89
💬
5. CYP19A1
×
告示番号
日本語名
英語名
81
先天性副腎皮質酵素欠損症
Congenital adrenal hyperplasia
89
リンパ脈管筋腫症
Lymphangioleiomyomatosis
6
ALOX5
💬
6. ALOX5
×
Name
Full Name
ALOX5
arachidonate 5-lipoxygenase
6件:
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
Fc epsilon RI signaling pathway
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Toxoplasmosis
6件:
Arachidonic acid metabolism
,
Metabolic pathways
,
Fc epsilon RI signaling pathway
,
Serotonergic s
...
Zileuton
Zileuton
💬
6. ALOX5
×
Name
Other Names
Zileuton
Zileuton (USP/INN)
Zyflo (TN)
ジロートン
Zileuton
3件:
85
85
,
160
,
164
💬
6. ALOX5
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
160
先天性魚鱗癬
Congenital ichthyosis
164
眼皮膚白皮症
Oculocutaneous albinism
7
ALOX5
💬
7. ALOX5
×
Name
Full Name
ALOX5
arachidonate 5-lipoxygenase
6件:
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
Fc epsilon RI signaling pathway
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Toxoplasmosis
6件:
Arachidonic acid metabolism
,
Metabolic pathways
,
Fc epsilon RI signaling pathway
,
Serotonergic s
...
Oxatomide
Oxatomide
💬
7. ALOX5
×
Name
Other Names
Oxatomide
Oxatomide (JAN/USAN/INN)
Celtect (TN)
オキサトミド
Oxatomide
1件:
113
113
💬
7. ALOX5
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
8
IGF1R
💬
8. IGF1R
×
Name
Full Name
IGF1R
insulin like growth factor 1 receptor
29件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Oocyte meiosis
,
Autophagy - animal
,
Endocytosis
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Focal adhesion
,
Adherens junction
,
Signaling pathways regulating pluripotency of stem cells
,
Long-term depression
,
Ovarian steroidogenesis
,
Progesterone-mediated oocyte maturation
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Proteoglycans in cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Breast cancer
,
Hepatocellular carcinoma
29件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras si
...
Mecasermin
Mecasermin
💬
8. IGF1R
×
Name
Other Names
Mecasermin
Mecasermin (USAN/INN)
Mecasermin (genetical recombination) (JAN)
Increlex (TN)
Myotrophin (TN)
メカセルミン
ソマゾン
Mecasermin
6件:
65
65
,
78
,
96
,
168
,
265
,
299
💬
8. IGF1R
×
告示番号
日本語名
英語名
65
原発性免疫不全症候群
Primary immunodeficiency
78
下垂体前葉機能低下症
Hypopituitarism
96
クローン病;回腸末端炎
Crohn disease
168
エーラス・ダンロス症候群
Ehlers-Danlos syndrome
265
脂肪萎縮症
Lipodystrophy
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
9
IGF1R
💬
9. IGF1R
×
Name
Full Name
IGF1R
insulin like growth factor 1 receptor
29件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Oocyte meiosis
,
Autophagy - animal
,
Endocytosis
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Focal adhesion
,
Adherens junction
,
Signaling pathways regulating pluripotency of stem cells
,
Long-term depression
,
Ovarian steroidogenesis
,
Progesterone-mediated oocyte maturation
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Proteoglycans in cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Breast cancer
,
Hepatocellular carcinoma
29件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras si
...
Teprotumumab
Teprotumumab
💬
9. IGF1R
×
Name
Other Names
Teprotumumab
Teprotumumab (USAN/INN)
Teprotumumab-trbw
Tepezza (TN)
テプロツムマブ
Teprotumumab
1件:
51
51
💬
9. IGF1R
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
10
IGF1R
💬
10. IGF1R
×
Name
Full Name
IGF1R
insulin like growth factor 1 receptor
29件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
HIF-1 signaling pathway
,
FoxO signaling pathway
,
Oocyte meiosis
,
Autophagy - animal
,
Endocytosis
,
mTOR signaling pathway
,
PI3K-Akt signaling pathway
,
AMPK signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Focal adhesion
,
Adherens junction
,
Signaling pathways regulating pluripotency of stem cells
,
Long-term depression
,
Ovarian steroidogenesis
,
Progesterone-mediated oocyte maturation
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Proteoglycans in cancer
,
Glioma
,
Prostate cancer
,
Melanoma
,
Breast cancer
,
Hepatocellular carcinoma
29件:
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
MAPK signaling pathway
,
Ras si
...
Linsitinib
Linsitinib
💬
10. IGF1R
×
Name
Other Names
Linsitinib
Linsitinib (USAN/INN)
リンシチニブ
Linsitinib
1件:
232
232
💬
10. IGF1R
×
告示番号
日本語名
英語名
232
カーニー複合
Carney complex