Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Hepatitis B 💬
 1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Hepatitis B 💬
 1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
3 Hepatitis B 💬
 2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
4 Hepatitis B 💬
 1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
5 Hepatitis B 💬
 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
6 Hepatitis B 💬
 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
7 Hepatitis B 💬
 1件: IFNAR1 💬 D11082 💬 Anifrolumab 3件: 46, 49, 53 💬
8 Hepatitis B 💬
 1件: IFNAR1 💬 D03305 💬 Interferon alfa 6件: 13, 25, 26, 28, 56, 96 💬
9 Hepatitis B 💬
 1件: IFNAR1 💬 D00745 💬 Interferon alfa-2a 1件: 56 💬
10 Hepatitis B 💬
 1件: IFNAR1 💬 D02745 💬 Interferon alfa-2b 2件: 25, 34 💬
11 Hepatitis B 💬
 1件: IFNAR1 💬 D04554 💬 Interferon beta-1a 4件: 13, 26, 96, 97 💬
12 Hepatitis B 💬
 1件: IFNAR1 💬 D00746 💬 Interferon beta-1b 1件: 13 💬
13 Hepatitis B 💬
 1件: IFNAR1 💬 D10483 💬 Peginterferon beta-1a 1件: 13 💬
14 Hepatitis B 💬
 1件: IL6 💬 D12487 💬 Olokizumab 2件: 46, 96 💬
15 Hepatitis B 💬
 1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
16 Hepatitis B 💬
 1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
17 Hepatitis B 💬
 2件: IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
18 Hepatitis B 💬
 2件: IL6, TNF 💬 D08976 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬
19 Hepatitis B 💬
 1件: JAK1 💬 D11400 💬 Abrocitinib 1件: 84 💬
20 Hepatitis B 💬
 1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
21 Hepatitis B 💬
 1件: JAK1 💬 D10944 💬 Itacitinib 4件: 46, 51, 97, 228 💬
22 Hepatitis B 💬
 1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
23 Hepatitis B 💬
 2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
24 Hepatitis B 💬
 2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 3件: 60, 65, 228 💬
25 Hepatitis B 💬
 3件: JAK1, JAK2, JAK3 💬 D10653 💬 Peficitinib 1件: 46 💬
26 Hepatitis B 💬
 4件: JAK1, JAK2, JAK3, TYK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
27 Hepatitis B 💬
 2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
28 Hepatitis B 💬
 2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
29 Hepatitis B 💬
 2件: MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib 1件: 34 💬
30 Hepatitis B 💬
 2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
31 Hepatitis B 💬
 2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
32 Hepatitis B 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
33 Hepatitis B 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
34 Hepatitis B 💬
 1件: NFKB1 💬 D01146 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
35 Hepatitis B 💬
 1件: PIK3CA 💬 D11011 💬 Alpelisib 1件: 138 💬
36 Hepatitis B 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
37 Hepatitis B 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
38 Hepatitis B 💬
 1件: PRKCB 💬 D11935 💬 Enzastaurin 1件: 168 💬
39 Hepatitis B 💬
 1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
40 Hepatitis B 💬
 1件: SLC10A1 💬 D10951 💬 Maralixibat 3件: 296, 297, 338 💬
41 Hepatitis B 💬
 1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
42 Hepatitis B 💬
 1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
43 Hepatitis B 💬
 1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
44 Hepatitis B 💬
 1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
45 Hepatitis B 💬
 3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 3件: 51, 85, 222 💬
46 Hepatitis B 💬
 1件: TNF 💬 D02597 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
47 Hepatitis B 💬
 1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
48 Hepatitis B 💬
 1件: TNF 💬 D00742 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
49 Hepatitis B 💬
 1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
50 Hepatitis B 💬
 1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
51 Hepatitis B 💬
 1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
52 Hepatitis B 💬
 1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
53 Hepatitis B 💬
 1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
54 Hepatitis B 💬
 1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
55 Hepatitis B 💬
 1件: TYK2 💬 D11817 💬 Deucravacitinib 3件: 49, 96, 97 💬