Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	SV2C	[1] ECM-receptor interaction	D11842	Padsevonil	[1] 149
2	ITGA4	[11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineag ...	D06590	Firategrast	[1] 13
3	ITGA4	[11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineag ...	D06886	Natalizumab	[6] 13, 15, 25, 46, 63, 96
4	ITGA4	[11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineag ...	D08083	Vedolizumab	[3] 94, 96, 97
5	ITGA4	[11] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineag ...	D10540	Abrilumab	[2] 96, 97
6	ITGB7	[8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network ...	D08083	Vedolizumab	[3] 94, 96, 97
7	ITGB7	[8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network ...	D09901	Etrolizumab	[2] 96, 97
8	ITGB7	[8] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Intestinal immune network ...	D10540	Abrilumab	[2] 96, 97
9	VWF	[6] PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Platelet activation, Neutr ...	D11160	Caplacizumab	[1] 64
10	SV2B	[1] ECM-receptor interaction	D11842	Padsevonil	[1] 149

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