Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Regulation of actin cytoskeleton 💬	[1] BRAF 💬	D10064 💬	Dabrafenib	[1] 34 💬
2	Regulation of actin cytoskeleton 💬	[3] BRAF, PDGFRB, RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
3	Regulation of actin cytoskeleton 💬	[1] C5 💬	D11696 💬	Crovalimab	[2] 62, 109 💬
4	Regulation of actin cytoskeleton 💬	[1] C5 💬	D03940 💬	Eculizumab	[7] 11, 13, 14, 61, 62, 109, 222 💬
5	Regulation of actin cytoskeleton 💬	[1] C5 💬	D11473 💬	Nomacopan	[3] 62, 109, 162 💬
6	Regulation of actin cytoskeleton 💬	[1] C5 💬	D11477 💬	Pozelimab	[2] 11, 62 💬
7	Regulation of actin cytoskeleton 💬	[1] C5 💬	D11054 💬	Ravulizumab	[7] 2 , 11, 13, 50, 62, 66, 109 💬
8	Regulation of actin cytoskeleton 💬	[1] C5 💬	D11838 💬	Vilobelimab	[3] 43, 44, 269 💬
9	Regulation of actin cytoskeleton 💬	[1] C5 💬	D12357 💬	Zilucoplan	[3] 2 , 11, 62 💬
10	Regulation of actin cytoskeleton 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	D00113 💬	Atropine	[2] 2 , 299 💬

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