Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	FDPS	[1] Terpenoid backbone biosynthesis	D01968	Zoledronic acid	[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
2	FDPS	[1] Terpenoid backbone biosynthesis	D07119	Alendronic acid	[7] 19, 41, 46, 50, 271, 274, 299
3	FDPS	[1] Terpenoid backbone biosynthesis	D07281	Pamidronic acid	[3] 270, 271, 274
4	FDPS	[1] Terpenoid backbone biosynthesis	D08484	Risedronic acid	[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
5	FDPS	[1] Terpenoid backbone biosynthesis	D08689	Zoledronic acid	[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
6	FNTA	[1] Terpenoid backbone biosynthesis	D03720	Tipifarnib	[1] 34
7	FNTA	[1] Terpenoid backbone biosynthesis	D04768	Lonafarnib	[2] 113, 333
8	FNTB	[1] Terpenoid backbone biosynthesis	D03720	Tipifarnib	[1] 34
9	FNTB	[1] Terpenoid backbone biosynthesis	D04768	Lonafarnib	[2] 113, 333
10	HMGCR	[1] Terpenoid backbone biosynthesis	D00359	Lovastatin	[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310

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