Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alcoholism 💬	[1] DRD2 💬	D00270 💬	Chlorpromazine	[1] 254 💬
2	Alzheimer disease 💬	[3] CHRM1, CHRM3, CHRM5 💬	D00270 💬	Chlorpromazine	[1] 254 💬
3	Biosynthesis of cofactors 💬	[1] ALAS1 💬	D11702 💬	Givosiran	[1] 254 💬
4	Biosynthesis of cofactors 💬	[2] ALAS1, ALAS2 💬	D10003 💬	Hemin	[1] 254 💬
5	Calcium signaling pathway 💬	[8] CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2A, HTR2B, HTR2C 💬	D00270 💬	Chlorpromazine	[1] 254 💬
6	Calcium signaling pathway 💬	[1] HRH2 💬	D00295 💬	Cimetidine	[2] 2 , 254 💬
7	cAMP signaling pathway 💬	[3] CHRM1, CHRM2, DRD2 💬	D00270 💬	Chlorpromazine	[1] 254 💬
8	cGMP-PKG signaling pathway 💬	[3] ADRA2A, ADRA2B, ADRA2C 💬	D00270 💬	Chlorpromazine	[1] 254 💬
9	Chemical carcinogenesis - reactive oxygen species 💬	[1] HMOX1 💬	D05922 💬	Stannsoporfin	[1] 254 💬
10	Cholinergic synapse 💬	[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬	D00270 💬	Chlorpromazine	[1] 254 💬

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