Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CHRM1 [8] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
2 CHRM2 [6] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
3 CHRM3 [11] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
4 CHRM4 [3] Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton D00270 Chlorpromazine [1] 254
5 CHRM5 [6] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine [1] 254
6 ADRA2A [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00270 Chlorpromazine [1] 254
7 ADRA2B [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00270 Chlorpromazine [1] 254
8 ADRA2C [2] cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction D00270 Chlorpromazine [1] 254
9 DRD2 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00270 Chlorpromazine [1] 254
10 ALAS1 [4] Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors D10003 Hemin [1] 254
11 ALAS1 [4] Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors D11702 Givosiran [1] 254
12 ALAS2 [4] Glycine, serine and threonine metabolism, Porphyrin metabolism, Metabolic pathways, Biosynthesis of cofactors D10003 Hemin [1] 254
13 HMOX1 [10] Porphyrin metabolism, Metabolic pathways, HIF-1 signaling pathway, Ferroptosis, Mineral absorption, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D05922 Stannsoporfin [1] 254
14 HMOX2 [3] Porphyrin metabolism, Metabolic pathways, Mineral absorption D05922 Stannsoporfin [1] 254
15 HRH1 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D00270 Chlorpromazine [1] 254
16 HRH2 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gastric acid secretion D00295 Cimetidine [2] 2, 254
17 HTR2A [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D00270 Chlorpromazine [1] 254
18 HTR2B [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D00270 Chlorpromazine [1] 254
19 HTR2C [5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels D00270 Chlorpromazine [1] 254
20 MC1R [2] Neuroactive ligand-receptor interaction, Melanogenesis D10511 Afamelanotide [3] 159, 161, 254