Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adherens junction 💬	[1] IGF1R 💬	D03297 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬
2	Alcoholism 💬	[1] ADORA2A 💬	D00528 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
3	Alcoholism 💬	[1] ADORA2A 💬	D01453 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
4	Alcoholism 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D03742 💬	Dextromethorphan	[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
5	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
6	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	D00528 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
7	Aldosterone synthesis and secretion 💬	[1] PDE2A 💬	D01453 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
8	Alzheimer disease 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D03742 💬	Dextromethorphan	[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
9	Alzheimer disease 💬	[1] PTGS2 💬	D07816 💬	Diclofenac	[5] 13, 34, 46, 78, 271 💬
10	Amphetamine addiction 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D03742 💬	Dextromethorphan	[11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬

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