Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
BCL2 [1] BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 [1] 28 💬 |
2 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
3 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
BRAF [5] BRAF, FLT4, KDR, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
4 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
5 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
6 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
7 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
8 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
9 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [2] EGFR, ERBB2 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
10 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
EGFR [4] EGFR, ERBB2, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
11 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
12 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
13 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
14 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FLT1 [5] FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
15 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FYN [3] FYN, PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
16 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
FYN [3] FYN, PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
17 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
18 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
19 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
20 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
21 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
22 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
23 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
24 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
25 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
KDR [2] KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
26 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
27 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
28 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
29 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
30 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
MAP2K1 [1] MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
31 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
32 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
33 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PGF [3] PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
34 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
35 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
36 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
37 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
38 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
39 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [2] 51, 85 💬 |
40 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
41 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
42 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
43 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
44 | Focal adhesion 💬 Related to 27 target genes, 43 drugs (DrugBank) and 44 diseases in DDrare |
VWF [1] VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 [1] 64 💬 |