Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Platelet activation 💬
 [1] BTK 💬 D10893 💬 Acalabrutinib [2] 46, 61 💬
2 Platelet activation 💬
 [1] BTK 💬 D11478 💬 Branebrutinib [3] 46, 49, 53 💬
3 Platelet activation 💬
 [1] BTK 💬 D12467 💬 Evobrutinib [3] 13, 46, 49 💬
4 Platelet activation 💬
 [1] BTK 💬 D11457 💬 Fenebrutinib [1] 13 💬
5 Platelet activation 💬
 [1] BTK 💬 D10223 💬 Ibrutinib [3] 28, 60, 61 💬
6 Platelet activation 💬
 [1] BTK 💬 D12160 💬 Orelabrutinib [4] 13, 49, 61, 63 💬
7 Platelet activation 💬
 [1] BTK 💬 D12285 💬 Remibrutinib [2] 13, 53 💬
8 Platelet activation 💬
 [1] BTK 💬 D11422 💬 Zanubrutinib [5] 13, 63, 222, 300, 331 💬
9 Platelet activation 💬
 [1] F2 💬 D09707 💬 Dabigatran [5] 51, 75, 85, 91, 124 💬
10 Platelet activation 💬
 [1] F2 💬 D07144 💬 Dabigatran etexilate [2] 51, 75 💬
11 Platelet activation 💬
 [1] F2 💬 D06410 💬 Thrombomodulin Alfa [1] 85 💬
12 Platelet activation 💬
 [2] FYN, SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
13 Platelet activation 💬
 [2] FYN, SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
14 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
15 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
16 Platelet activation 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
17 Platelet activation 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
18 Platelet activation 💬
 [1] P2RY12 💬 D07729 💬 Clopidogrel [3] 49, 51, 86 💬
19 Platelet activation 💬
 [1] P2RY12 💬 D10823 💬 Clopidogrel [3] 49, 51, 86 💬
20 Platelet activation 💬
 [1] P2RY12 💬 D10824 💬 Clopidogrel [3] 49, 51, 86 💬
21 Platelet activation 💬
 [1] P2RY12 💬 D09017 💬 Ticagrelor [3] 36, 46, 85 💬
22 Platelet activation 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
23 Platelet activation 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
24 Platelet activation 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
25 Platelet activation 💬
 [1] PTGIR 💬 D02720 💬 Beraprost [1] 86 💬
26 Platelet activation 💬
 [1] PTGIR 💬 D00106 💬 Epoprostenol [1] 86 💬
27 Platelet activation 💬
 [1] PTGIR 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
28 Platelet activation 💬
 [1] PTGIR 💬 D02721 💬 Iloprost [4] 51, 84, 85, 86 💬
29 Platelet activation 💬
 [1] PTGIR 💬 D10725 💬 Ralinepag [1] 86 💬
30 Platelet activation 💬
 [1] PTGIR 💬 D09994 💬 Selexipag [5] 51, 70, 84, 86, 88 💬
31 Platelet activation 💬
 [1] PTGIR 💬 D06213 💬 Treprostinil [6] 51, 84, 85, 86, 88, 210 💬
32 Platelet activation 💬
 [1] PTGS1 💬 D01545 💬 Aceclofenac [1] 46 💬
33 Platelet activation 💬
 [1] PTGS1 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
34 Platelet activation 💬
 [1] PTGS1 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
35 Platelet activation 💬
 [1] PTGS1 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
36 Platelet activation 💬
 [1] PTGS1 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
37 Platelet activation 💬
 [1] PTGS1 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
38 Platelet activation 💬
 [1] PTGS1 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
39 Platelet activation 💬
 [1] PTGS1 💬 D00132 💬 Ketoprofen [1] 46 💬
40 Platelet activation 💬
 [1] PTGS1 💬 D08104 💬 Ketorolac [2] 70, 226 💬
41 Platelet activation 💬
 [1] PTGS1 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
42 Platelet activation 💬
 [1] PTGS1 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
43 Platelet activation 💬
 [1] PTGS1 💬 D00428 💬 Salsalate [1]  5  💬
44 Platelet activation 💬
 [1] PTGS1 💬 D00120 💬 Sulindac [1] 206 💬
45 Platelet activation 💬
 [1] PTGS1 💬 D01183 💬 Tolfenamic acid [1]  5  💬
46 Platelet activation 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
47 Platelet activation 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [2] 51, 85 💬
48 Platelet activation 💬
 [1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
49 Platelet activation 💬
 [1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬
50 Platelet activation 💬
 [1] SYK 💬 D09347 💬 Fostamatinib [4] 46, 49, 61, 66 💬
51 Platelet activation 💬
 [1] TBXA2R 💬 D01896 💬 Cilostazol [3] 46, 51, 70 💬
52 Platelet activation 💬
 [1] TBXA2R 💬 D04500 💬 Ifetroban [2] 85, 113 💬
53 Platelet activation 💬
 [1] TBXA2R 💬 D01128 💬 Ramatroban [1] 13 💬
54 Platelet activation 💬
 [1] VWF 💬 D11160 💬 Caplacizumab [1] 64 💬