Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 D07119 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
2 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 D07281 💬 Pamidronic acid [3] 270, 271, 274 💬
3 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 D08484 💬 Risedronic acid [9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
4 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 D01968 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
5 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 D08689 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
6 Terpenoid backbone biosynthesis 💬
 [2] FNTA, FNTB 💬 D04768 💬 Lonafarnib [2] 113, 333 💬
7 Terpenoid backbone biosynthesis 💬
 [2] FNTA, FNTB 💬 D03720 💬 Tipifarnib [1] 34 💬
8 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D07474 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D07983 💬 Fluvastatin [3] 79, 218, 222 💬
10 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00359 💬 Lovastatin [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
11 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D08410 💬 Pravastatin [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
12 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D08492 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
13 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 D00434 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬